BCAP31 | ENSG00000185825 | NCBI 10134

Details for: BCAP31

Gene ID: 10134

Symbol: BCAP31

Ensembl ID: ENSG00000185825

Description: B cell receptor associated protein 31

Associated with

Adaptive immune system
(R-HSA-1280218)
Antigen presentation: folding, assembly and peptide loading of class i mhc
(R-HSA-983170)
Apoptosis
(R-HSA-109581)
Apoptotic cleavage of cellular proteins
(R-HSA-111465)
Apoptotic execution phase
(R-HSA-75153)
Class i mhc mediated antigen processing & presentation
(R-HSA-983169)
Disease
(R-HSA-1643685)
Immune system
(R-HSA-168256)
Infectious disease
(R-HSA-5663205)
Programmed cell death
(R-HSA-5357801)
Respiratory syncytial virus infection pathway
(R-HSA-9820952)
Rhoa gtpase cycle
(R-HSA-8980692)
Rho gtpase cycle
(R-HSA-9012999)
Rsv-host interactions
(R-HSA-9833110)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
Viral infection pathways
(R-HSA-9824446)
Apoptotic process
(GO:0006915)
Calcium-mediated signaling using intracellular calcium source
(GO:0035584)
Clathrin-coated vesicle
(GO:0030136)
Cytosol
(GO:0005829)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum-golgi intermediate compartment membrane
(GO:0033116)
Endoplasmic reticulum membrane
(GO:0005789)
Endoplasmic reticulum to golgi vesicle-mediated transport
(GO:0006888)
Golgi cisterna membrane
(GO:0032580)
Golgi membrane
(GO:0000139)
Intracellular protein transport
(GO:0006886)
Lipid droplet
(GO:0005811)
Lumenal side of endoplasmic reticulum membrane
(GO:0098553)
Membrane
(GO:0016020)
Mhc class i protein binding
(GO:0042288)
Mitochondria-associated endoplasmic reticulum membrane
(GO:0044233)
Mitochondrion
(GO:0005739)
Negative regulation of endoplasmic reticulum calcium ion concentration
(GO:0032471)
Perinuclear endoplasmic reticulum
(GO:0097038)
Plasma membrane
(GO:0005886)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0043280)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of erad pathway
(GO:1904294)
Positive regulation of intrinsic apoptotic signaling pathway
(GO:2001244)
Positive regulation of mitochondrial calcium ion concentration
(GO:0051561)
Positive regulation of retrograde protein transport, er to cytosol
(GO:1904154)
Positive regulation of ubiquitin-dependent protein catabolic process
(GO:2000060)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein localization to endoplasmic reticulum exit site
(GO:0070973)
Protein targeting to mitochondrion
(GO:0006626)
Response to endoplasmic reticulum stress
(GO:0034976)
Spermatogenesis
(GO:0007283)

Other Information

Proteins

B-cell receptor-associated protein 31

Genular Protein ID: 1889894876

Symbol: BAP31_HUMAN

Name: B-cell receptor-associated protein 31

UniProtKB Accession Codes:

P51572 B3KQ79 D3DWV5 Q13836 Q96CF0

Database IDs:

Citations:

PubMed ID: 7806238

Title: A new human gene (DXS1357E) with ubiquitous expression, located in Xq28 adjacent to the adrenoleukodystrophy gene.

PubMed ID: 7806238

DOI: 10.1006/geno.1994.1413

PubMed ID: 8706661

Title: Molecular cloning and characterization of a transmembrane surface antigen in human cells.

PubMed ID: 8706661

DOI: 10.1111/j.1432-1033.1996.0631w.x

PubMed ID: 8612576

Title: The specificity of association of the IgD molecule with the accessory proteins BAP31/BAP29 lies in the IgD transmembrane sequence.

PubMed ID: 8612576

DOI: 10.1002/j.1460-2075.1996.tb00497.x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9334338

Title: p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum.

PubMed ID: 9334338

DOI: 10.1083/jcb.139.2.327

PubMed ID: 9396746

Title: Export of cellubrevin from the endoplasmic reticulum is controlled by BAP31.

PubMed ID: 9396746

DOI: 10.1083/jcb.139.6.1397

PubMed ID: 10958671

Title: Caspase-resistant BAP31 inhibits Fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondria.

PubMed ID: 10958671

DOI: 10.1128/mcb.20.18.6731-6740.2000

PubMed ID: 11042173

Title: Proteomics characterization of abundant Golgi membrane proteins.

PubMed ID: 11042173

DOI: 10.1074/jbc.m006143200

PubMed ID: 11561007

Title: Endoplasmic reticulum membrane-sorting protein of lymphocytes (BAP31) is highly expressed in neurons and discrete endocrine cells.

PubMed ID: 11561007

DOI: 10.1177/002215540104901005

PubMed ID: 11917123

Title: The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum.

PubMed ID: 11917123

DOI: 10.1073/pnas.072088099

PubMed ID: 15024066

Title: The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B.

PubMed ID: 15024066

DOI: 10.1128/mcb.24.7.2767-2778.2004

PubMed ID: 11992258

Title: Contiguous deletion of the X-linked adrenoleukodystrophy gene (ABCD1) and DXS1357E: a novel neonatal phenotype similar to peroxisomal biogenesis disorders.

PubMed ID: 11992258

DOI: 10.1086/340849

PubMed ID: 18287538

Title: Bap31 is an itinerant protein that moves between the peripheral endoplasmic reticulum (ER) and a juxtanuclear compartment related to ER-associated Degradation.

PubMed ID: 18287538

DOI: 10.1091/mbc.e07-08-0781

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24011989

Title: Mutations in BCAP31 cause a severe X-linked phenotype with deafness, dystonia, and central hypomyelination and disorganize the Golgi apparatus.

PubMed ID: 24011989

DOI: 10.1016/j.ajhg.2013.07.023

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24196833

Title: Mutations in Fis1 disrupt orderly disposal of defective mitochondria.

PubMed ID: 24196833

DOI: 10.1091/mbc.e13-09-0525

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 25854864

Title: Interaction between human BAP31 and respiratory syncytial virus small hydrophobic (SH) protein.

PubMed ID: 25854864

DOI: 10.1016/j.virol.2015.03.034

PubMed ID: 31206022

Title: BAP31 regulates mitochondrial function via interaction with Tom40 within ER-mitochondria contact sites.

PubMed ID: 31206022

DOI: 10.1126/sciadv.aaw1386

PubMed ID: 25631089

Title: The endoplasmic reticulum membrane J protein C18 executes a distinct role in promoting simian virus 40 membrane penetration.

PubMed ID: 25631089

DOI: 10.1128/jvi.03574-14

PubMed ID: 23967155

Title: Structural and biophysical characterization of the cytoplasmic domains of human BAP29 and BAP31.

PubMed ID: 23967155

DOI: 10.1371/journal.pone.0071111

Sequence Information:

Length: 246
Mass: 27992
Checksum: D34367F870D6EB00
Sequence:

MSLQWTAVAT FLYAEVFVVL LLCIPFISPK RWQKIFKSRL VELLVSYGNT FFVVLIVILV 
LLVIDAVREI RKYDDVTEKV NLQNNPGAME HFHMKLFRAQ RNLYIAGFSL LLSFLLRRLV 
TLISQQATLL ASNEAFKKQA ESASEAAKKY MEENDQLKKG AAVDGGKLDV GNAEVKLEEE 
NRSLKADLQK LKDELASTKQ KLEKAENQVL AMRKQSEGLT KEYDRLLEEH AKLQAAVDGP 
MDKKEE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: BCAP31

Associated with

Other Information

A new human gene (DXS1357E) with ubiquitous expression, located in Xq28 adjacent to the adrenoleukodystrophy gene. PubMed ID: 7806238

Molecular cloning and characterization of a transmembrane surface antigen in human cells. PubMed ID: 8706661

The specificity of association of the IgD molecule with the accessory proteins BAP31/BAP29 lies in the IgD transmembrane sequence. PubMed ID: 8612576

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence of the human X chromosome. PubMed ID: 15772651

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum. PubMed ID: 9334338

Export of cellubrevin from the endoplasmic reticulum is controlled by BAP31. PubMed ID: 9396746

Caspase-resistant BAP31 inhibits Fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondria. PubMed ID: 10958671

Proteomics characterization of abundant Golgi membrane proteins. PubMed ID: 11042173

Endoplasmic reticulum membrane-sorting protein of lymphocytes (BAP31) is highly expressed in neurons and discrete endocrine cells. PubMed ID: 11561007

The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum. PubMed ID: 11917123

The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B. PubMed ID: 15024066

Contiguous deletion of the X-linked adrenoleukodystrophy gene (ABCD1) and DXS1357E: a novel neonatal phenotype similar to peroxisomal biogenesis disorders. PubMed ID: 11992258

Bap31 is an itinerant protein that moves between the peripheral endoplasmic reticulum (ER) and a juxtanuclear compartment related to ER-associated Degradation. PubMed ID: 18287538

Initial characterization of the human central proteome. PubMed ID: 21269460

Mutations in BCAP31 cause a severe X-linked phenotype with deafness, dystonia, and central hypomyelination and disorganize the Golgi apparatus. PubMed ID: 24011989

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Mutations in Fis1 disrupt orderly disposal of defective mitochondria. PubMed ID: 24196833

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Interaction between human BAP31 and respiratory syncytial virus small hydrophobic (SH) protein. PubMed ID: 25854864

BAP31 regulates mitochondrial function via interaction with Tom40 within ER-mitochondria contact sites. PubMed ID: 31206022

The endoplasmic reticulum membrane J protein C18 executes a distinct role in promoting simian virus 40 membrane penetration. PubMed ID: 25631089

Structural and biophysical characterization of the cytoplasmic domains of human BAP29 and BAP31. PubMed ID: 23967155