NAMPT | ENSG00000105835 | NCBI 10135

Details for: NAMPT

Gene ID: 10135

Symbol: NAMPT

Ensembl ID: ENSG00000105835

Description: nicotinamide phosphoribosyltransferase

Associated with

Bmal1:clock,npas2 activates circadian gene expression
(R-HSA-1368108)
Circadian clock
(R-HSA-400253)
Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Metabolism
(R-HSA-1430728)
Metabolism of vitamins and cofactors
(R-HSA-196854)
Metabolism of water-soluble vitamins and cofactors
(R-HSA-196849)
Nicotinamide salvaging
(R-HSA-197264)
Nicotinate metabolism
(R-HSA-196807)
Npas4 regulates expression of target genes
(R-HSA-9768919)
Rna polymerase ii transcription
(R-HSA-73857)
Transcriptional regulation by npas4
(R-HSA-9634815)
Adipose tissue development
(GO:0060612)
Cell-cell signaling
(GO:0007267)
Cell junction
(GO:0030054)
Circadian regulation of gene expression
(GO:0032922)
Cytokine activity
(GO:0005125)
Cytosol
(GO:0005829)
Extracellular exosome
(GO:0070062)
Identical protein binding
(GO:0042802)
Insulin receptor signaling pathway
(GO:0008286)
Nad biosynthesis via nicotinamide riboside salvage pathway
(GO:0034356)
Nad biosynthetic process
(GO:0009435)
Nicotinamide phosphoribosyltransferase activity
(GO:0047280)
Nuclear speck
(GO:0016607)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of nitric-oxide synthase biosynthetic process
(GO:0051770)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Signal transduction
(GO:0007165)

Other Information

Proteins

Nicotinamide phosphoribosyltransferase

Genular Protein ID: 101556671

Symbol: NAMPT_HUMAN

Name: Nicotinamide phosphoribosyltransferase

UniProtKB Accession Codes:

P43490 A4D0Q9 A4D0R0 Q3KQV0 Q8WW95

Database IDs:

Citations:

PubMed ID: 8289818

Title: Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor.

PubMed ID: 8289818

DOI: 10.1128/mcb.14.2.1431-1437.1994

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22462624

Title: Visfatin/NAMPT: a multifaceted molecule with diverse roles in physiology and pathophysiology.

PubMed ID: 22462624

DOI: 10.1146/annurev-nutr-071811-150746

PubMed ID: 21741723

Title: Visfatin is secreted into the breast milk and is correlated with weight changes of the infant after the birth.

PubMed ID: 21741723

DOI: 10.1016/j.diabres.2011.06.009

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24130902

Title: Visfatin as a novel mediator released by inflamed human endothelial cells.

PubMed ID: 24130902

DOI: 10.1371/journal.pone.0078283

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 16783377

Title: Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.

PubMed ID: 16783377

DOI: 10.1038/nsmb1105

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

Length: 491
Mass: 55521
Checksum: 6BF07B631B589AC0
Sequence:

MNPAAEAEFN ILLATDSYKV THYKQYPPNT SKVYSYFECR EKKTENSKLR KVKYEETVFY 
GLQYILNKYL KGKVVTKEKI QEAKDVYKEH FQDDVFNEKG WNYILEKYDG HLPIEIKAVP 
EGFVIPRGNV LFTVENTDPE CYWLTNWIET ILVQSWYPIT VATNSREQKK ILAKYLLETS 
GNLDGLEYKL HDFGYRGVSS QETAGIGASA HLVNFKGTDT VAGLALIKKY YGTKDPVPGY 
SVPAAEHSTI TAWGKDHEKD AFEHIVTQFS SVPVSVVSDS YDIYNACEKI WGEDLRHLIV 
SRSTQAPLII RPDSGNPLDT VLKVLEILGK KFPVTENSKG YKLLPPYLRV IQGDGVDINT 
LQEIVEGMKQ KMWSIENIAF GSGGGLLQKL TRDLLNCSFK CSYVVTNGLG INVFKDPVAD 
PNKRSKKGRL SLHRTPAGNF VTLEEGKGDL EEYGQDLLHT VFKNGKVTKS YSFDEIRKNA 
QLNIELEAAH H

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: NAMPT

Associated with

Other Information

Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. PubMed ID: 8289818

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence of human chromosome 7. PubMed ID: 12853948

Human chromosome 7: DNA sequence and biology. PubMed ID: 12690205

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. PubMed ID: 15592455

Initial characterization of the human central proteome. PubMed ID: 21269460

Visfatin/NAMPT: a multifaceted molecule with diverse roles in physiology and pathophysiology. PubMed ID: 22462624

Visfatin is secreted into the breast milk and is correlated with weight changes of the infant after the birth. PubMed ID: 21741723

Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features. PubMed ID: 22223895

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Visfatin as a novel mediator released by inflamed human endothelial cells. PubMed ID: 24130902

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. PubMed ID: 16783377

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974