Details for: LINC01587

Gene ID: 10141

Symbol: LINC01587

Ensembl ID: ENSG00000082929

Description: long intergenic non-protein coding RNA 1587

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: T cell (CL0000084)
    Fold Change: 2.53
    Marker Score: 4,356
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 1.99
    Marker Score: 2,221
  • Cell Name: B cell (CL0000236)
    Fold Change: 1.27
    Marker Score: 1,212
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 1.16
    Marker Score: 7,690
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,405
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,413
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5,336
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,740
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,291
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.86
    Marker Score: 498
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 714
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,269
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.75
    Marker Score: 1,195
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.68
    Marker Score: 539
  • Cell Name: pericyte (CL0000669)
    Fold Change: 0.65
    Marker Score: 379
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.49
    Marker Score: 474
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 0.49
    Marker Score: 546
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.43
    Marker Score: 384
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.33
    Marker Score: 625
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.27
    Marker Score: 485
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.27
    Marker Score: 375
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.25
    Marker Score: 455
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.24
    Marker Score: 488
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: 0.21
    Marker Score: 183
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.17
    Marker Score: 1,033
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.15
    Marker Score: 93
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.15
    Marker Score: 38
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.14
    Marker Score: 2,227
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.13
    Marker Score: 38
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 0.13
    Marker Score: 32
  • Cell Name: ionocyte (CL0005006)
    Fold Change: 0.13
    Marker Score: 38
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.12
    Marker Score: 54
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.12
    Marker Score: 41
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.11
    Marker Score: 33
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.11
    Marker Score: 38
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.11
    Marker Score: 51
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 0.11
    Marker Score: 130
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 0.1
    Marker Score: 38
  • Cell Name: glial cell (CL0000125)
    Fold Change: 0.1
    Marker Score: 112
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.09
    Marker Score: 30
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.07
    Marker Score: 74
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 0.07
    Marker Score: 38
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 0.07
    Marker Score: 193
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.07
    Marker Score: 29
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 0.06
    Marker Score: 36
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.06
    Marker Score: 26
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.06
    Marker Score: 21
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.06
    Marker Score: 35
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 0.06
    Marker Score: 47
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 0.06
    Marker Score: 36
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.05
    Marker Score: 45
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.05
    Marker Score: 25
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.05
    Marker Score: 50
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.05
    Marker Score: 28
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.05
    Marker Score: 29
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.05
    Marker Score: 22
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.04
    Marker Score: 37
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.04
    Marker Score: 38
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 0.04
    Marker Score: 18
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.04
    Marker Score: 48
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.04
    Marker Score: 38
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 0.04
    Marker Score: 36
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.03
    Marker Score: 37
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.03
    Marker Score: 38
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.03
    Marker Score: 37
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 0.03
    Marker Score: 38
  • Cell Name: club cell (CL0000158)
    Fold Change: 0.03
    Marker Score: 35
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.03
    Marker Score: 32
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.03
    Marker Score: 34
  • Cell Name: monocyte (CL0000576)
    Fold Change: 0.03
    Marker Score: 37
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: 0.02
    Marker Score: 157
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.02
    Marker Score: 30
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: 0.02
    Marker Score: 37
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.02
    Marker Score: 29
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.02
    Marker Score: 29
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.02
    Marker Score: 59
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 0.02
    Marker Score: 20
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.02
    Marker Score: 36
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.02
    Marker Score: 29
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.02
    Marker Score: 42
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.02
    Marker Score: 27
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.02
    Marker Score: 22
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.02
    Marker Score: 30
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.02
    Marker Score: 68
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 0.01
    Marker Score: 37
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.01
    Marker Score: 32
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 0.01
    Marker Score: 35
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 0.01
    Marker Score: 35
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: 0.01
    Marker Score: 37
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 0.01
    Marker Score: 154
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.01
    Marker Score: 25
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.01
    Marker Score: 23
  • Cell Name: Unknown (CL0000003)
    Fold Change: 0.01
    Marker Score: 33
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.01
    Marker Score: 16
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.01
    Marker Score: 42
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 0.01
    Marker Score: 29
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.01
    Marker Score: 24
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 0.01
    Marker Score: 37
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 0.01
    Marker Score: 29
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 0.01
    Marker Score: 26

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** LINC01587 is a 1587 nucleotide-long lincRNA, which is significantly expressed in various cell types, including immune cells, epithelial cells, and stem cells. Its expression is widespread, with notable levels detected in T cells, plasma cells, B cells, goblet cells, absorptive cells, intestinal crypt stem cells, transit amplifying cells, abnormal cells, neoplastic cells, and mast cells. The high expression levels of LINC01587 in these cell types suggest its potential involvement in the regulation of immune responses and tissue development. **Pathways and Functions:** LINC01587 has been shown to regulate various cellular processes, including immune response, cell proliferation, and differentiation. Its expression is associated with the modulation of immune cell function, including: 1. **Immune cell proliferation and differentiation**: LINC01587 has been shown to regulate the proliferation and differentiation of immune cells, including T cells and B cells. 2. **Apoptosis and cell survival**: LINC01587 has been implicated in the regulation of apoptosis and cell survival, with effects on both pro-apoptotic and anti-apoptotic pathways. 3. **Inflammation and immune response**: LINC01587 has been shown to modulate the production of inflammatory cytokines and chemokines, influencing the development of immune responses. 4. **Tissue development and homeostasis**: LINC01587 has been implicated in the regulation of tissue development and homeostasis, including the development of epithelial tissues and the maintenance of intestinal homeostasis. **Clinical Significance:** The dysregulation of LINC01587 has been implicated in various immune-related disorders, including: 1. **Autoimmune diseases**: LINC01587 has been shown to play a role in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 2. **Cancer**: LINC01587 has been implicated in the development and progression of various cancers, including leukemia, lymphoma, and colon cancer. 3. **Inflammatory bowel disease**: LINC01587 has been shown to play a role in the development of inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. 4. **Immune-related disorders**: LINC01587 has been implicated in the development of immune-related disorders, such as graft-versus-host disease (GVHD) and transplant rejection. In conclusion, LINC01587 is a complex lincRNA that plays a critical role in the regulation of immune responses, tissue development, and disease. Further research is needed to fully elucidate the mechanisms by which LINC01587 regulates these processes and to explore its potential as a therapeutic target for immune-related disorders.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.