EBI3 | ENSG00000105246 | NCBI 10148

Details for: EBI3

Gene ID: 10148

Symbol: EBI3

Ensembl ID: ENSG00000105246

Description: Epstein-Barr virus induced 3

Associated with

Cytokine signaling in immune system
(R-HSA-1280215)
Immune system
(R-HSA-168256)
Interleukin-12 family signaling
(R-HSA-447115)
Interleukin-27 signaling
(R-HSA-9020956)
Interleukin-35 signalling
(R-HSA-8984722)
Signaling by interleukins
(R-HSA-449147)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytokine activity
(GO:0005125)
Cytokine binding
(GO:0019955)
Cytokine receptor activity
(GO:0004896)
Endoplasmic reticulum lumen
(GO:0005788)
External side of plasma membrane
(GO:0009897)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Humoral immune response
(GO:0006959)
Interleukin-27 receptor binding
(GO:0045523)
Plasma membrane
(GO:0005886)
Positive regulation of alpha-beta t cell proliferation
(GO:0046641)
Positive regulation of type ii interferon production
(GO:0032729)
Protein binding
(GO:0005515)
Receptor complex
(GO:0043235)
T-helper 1 type immune response
(GO:0042088)
T cell proliferation
(GO:0042098)

Other Information

Proteins

Interleukin-27 subunit beta

Genular Protein ID: 2095356899

Symbol: IL27B_HUMAN

Name: Interleukin-27 subunit beta

UniProtKB Accession Codes:

Q14213 A0N0N2 O75269

Database IDs:

Citations:

PubMed ID: 8551575

Title: A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes.

PubMed ID: 8551575

DOI: 10.1128/jvi.70.2.1143-1153.1996

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9342359

Title: Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin.

PubMed ID: 9342359

DOI: 10.1073/pnas.94.22.12041

PubMed ID: 12121660

Title: IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells.

PubMed ID: 12121660

DOI: 10.1016/s1074-7613(02)00324-2

PubMed ID: 17294231

Title: The biology and therapeutic potential of interleukin 27.

PubMed ID: 17294231

DOI: 10.1007/s00109-007-0164-7

Sequence Information:

Length: 229
Mass: 25396
Checksum: CFBAD72D91859EF0
Sequence:

MTPQLLLALV LWASCPPCSG RKGPPAALTL PRVQCRASRY PIAVDCSWTL PPAPNSTSPV 
SFIATYRLGM AARGHSWPCL QQTPTSTSCT ITDVQLFSMA PYVLNVTAVH PWGSSSSFVP 
FITEHIIKPD PPEGVRLSPL AERQLQVQWE PPGSWPFPEI FSLKYWIRYK RQGAARFHRV 
GPIEATSFIL RAVRPRARYY VQVAAQDLTD YGELSDWSLP ATATMSLGK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: EBI3

Associated with

Other Information

A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes. PubMed ID: 8551575

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin. PubMed ID: 9342359

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells. PubMed ID: 12121660