Details for: ADGRG2

Gene ID: 10149

Symbol: ADGRG2

Ensembl ID: ENSG00000173698

Description: adhesion G protein-coupled receptor G2

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: amacrine cell (CL0000561)
    Fold Change: 9.87
    Marker Score: 31,629
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 5.15
    Marker Score: 15,260
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 3.53
    Marker Score: 29,823
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 1.96
    Marker Score: 877
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 1.78
    Marker Score: 23,706
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.75
    Marker Score: 852
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.6
    Marker Score: 1,166
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 169,008
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.37
    Marker Score: 868
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.26
    Marker Score: 854
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.15
    Marker Score: 4,811
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.11
    Marker Score: 623
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.09
    Marker Score: 501
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.07
    Marker Score: 2,439
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.04
    Marker Score: 795
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.02
    Marker Score: 3,765
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.98
    Marker Score: 507
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.98
    Marker Score: 407
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,408
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 460
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,412
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.95
    Marker Score: 382
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5,330
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.93
    Marker Score: 372
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,740
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 325
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 0.89
    Marker Score: 1,847
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,296
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.87
    Marker Score: 255
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.85
    Marker Score: 562
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: 0.82
    Marker Score: 306
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.82
    Marker Score: 2,045
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,266
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.77
    Marker Score: 707
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.76
    Marker Score: 445
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.72
    Marker Score: 1,466
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.72
    Marker Score: 460
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7
    Marker Score: 179
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.68
    Marker Score: 665
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 0.67
    Marker Score: 835
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 0.65
    Marker Score: 206
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.64
    Marker Score: 10,033
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.63
    Marker Score: 420
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.61
    Marker Score: 365
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.59
    Marker Score: 205
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 443
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 0.56
    Marker Score: 911
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.55
    Marker Score: 174
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 0.54
    Marker Score: 3,588
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 0.54
    Marker Score: 251
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.52
    Marker Score: 3,112
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.52
    Marker Score: 1,839
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.51
    Marker Score: 988
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.51
    Marker Score: 2,143
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 0.5
    Marker Score: 272
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.5
    Marker Score: 1,044
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.49
    Marker Score: 473
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.49
    Marker Score: 198
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.49
    Marker Score: 204
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.46
    Marker Score: 211
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.45
    Marker Score: 142
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.44
    Marker Score: 9,869
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.42
    Marker Score: 133
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.4
    Marker Score: 93
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.4
    Marker Score: 105
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.38
    Marker Score: 97
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.38
    Marker Score: 688
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.38
    Marker Score: 180
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.38
    Marker Score: 247
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.37
    Marker Score: 187
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.37
    Marker Score: 371
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.37
    Marker Score: 1,417
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 0.36
    Marker Score: 94
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.34
    Marker Score: 114
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.33
    Marker Score: 405
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.33
    Marker Score: 319
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.33
    Marker Score: 152
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.33
    Marker Score: 722
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.33
    Marker Score: 784
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 0.33
    Marker Score: 119
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.32
    Marker Score: 393
  • Cell Name: glandular cell of esophagus (CL0002657)
    Fold Change: 0.32
    Marker Score: 100
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.32
    Marker Score: 2,010
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.3
    Marker Score: 319
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 0.3
    Marker Score: 167
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.3
    Marker Score: 258
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.29
    Marker Score: 72
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.28
    Marker Score: 439
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.28
    Marker Score: 528
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.28
    Marker Score: 246
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: 0.28
    Marker Score: 81
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.27
    Marker Score: 10,125
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.27
    Marker Score: 155
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.26
    Marker Score: 753
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.26
    Marker Score: 84
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.25
    Marker Score: 597
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.25
    Marker Score: 2,167
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.25
    Marker Score: 707
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 0.25
    Marker Score: 705
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.24
    Marker Score: 195

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cellular localization:** ADGRG2 is primarily expressed on the cell surface, where it can interact with extracellular ligands and activate G protein-coupled signaling pathways. 2. **G protein-coupled receptor activity:** ADGRG2 belongs to the GPCR family, which is characterized by the ability to bind ligands and activate G proteins, leading to downstream signaling events. 3. **Wide tissue expression:** ADGRG2 is expressed in various tissues, including the retina, lung, heart, and gastrointestinal tract, suggesting its involvement in multiple biological processes. 4. **Cell type specificity:** ADGRG2 is specifically expressed in certain cell types, such as amacrine cells, OFF-bipolar cells, and cardiac muscle cells, indicating its role in specific cellular functions. **Pathways and Functions:** 1. **Adenylate cyclase-activating GPCR signaling pathway:** ADGRG2 activates the adenylate cyclase pathway, leading to increased cAMP levels and subsequent signaling events. 2. **G protein-coupled receptor signaling pathway:** ADGRG2 activates G protein-coupled receptor signaling pathways, which are involved in various cellular processes, including cell adhesion, migration, and proliferation. 3. **Spermatogenesis:** ADGRG2 is specifically expressed in the testis and plays a role in spermatogenesis, a complex process involving the development of sperm cells. 4. **Cell adhesion:** ADGRG2 interacts with extracellular ligands and plays a role in cell adhesion, a process critical for tissue organization and function. **Clinical Significance:** ADGRG2 has been implicated in various diseases and disorders, including: 1. **Retinal disorders:** ADGRG2 mutations have been associated with retinal disorders, such as retinitis pigmentosa and cone-rod dystrophy. 2. **Cardiovascular disease:** ADGRG2 has been linked to cardiovascular disease, including hypertension and cardiac arrhythmias. 3. **Gastrointestinal disorders:** ADGRG2 has been implicated in gastrointestinal disorders, such as inflammatory bowel disease and colon cancer. 4. **Immunological disorders:** ADGRG2 has been shown to play a role in immunological disorders, including autoimmune diseases and allergic reactions. In conclusion, ADGRG2 is a multifunctional GPCR that plays a crucial role in various cellular processes, including cell adhesion, signaling, and development. Its wide tissue expression and cell type specificity suggest its involvement in multiple biological processes, and its clinical significance highlights the importance of further research into its role in human disease.

Genular Protein ID: 2284373870

Symbol: AGRG2_HUMAN

Name: G-protein coupled receptor 64

UniProtKB Accession Codes:

Q8IZP9 B1AWB3 B1AWB4 B1AWB6 B1AWB7 O00406 Q14CE0 Q8IWT2 Q8IZE4 Q8IZE5 Q8IZE6 Q8IZE7 Q8IZP3 Q8IZP4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 8 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 EPD 1 Ensembl 10 GO 11 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 InterPro 5 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 3 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 10 Pumba 1 RNAct 1 RefSeq 12 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9150425

Title: Cloning of a human epididymis-specific mRNA, HE6, encoding a novel member of the seven transmembrane-domain receptor superfamily.

PubMed ID: 9150425

DOI: 10.1089/dna.1997.16.379

PubMed ID: 12420295

Title: HE6, a two-subunit heptahelical receptor associated with apical membranes of efferent and epididymal duct epithelia.

PubMed ID: 12420295

DOI: 10.1002/mrd.10220

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18469038

Title: HE6/GPR64 adhesion receptor co-localizes with apical and subapical F-actin scaffold in male excurrent duct epithelia.

PubMed ID: 18469038

DOI: 10.1530/rep-08-0078

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23338946

Title: G-Protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1.

PubMed ID: 23338946

DOI: 10.1002/path.4170

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25713288

Title: International union of basic and clinical pharmacology. XCIV. Adhesion G protein-coupled receptors.

PubMed ID: 25713288

DOI: 10.1124/pr.114.009647

PubMed ID: 27476656

Title: Truncating mutations in the adhesion G protein-coupled receptor G2 gene ADGRG2 cause an X-Linked congenital bilateral absence of vas deferens.

PubMed ID: 27476656

DOI: 10.1016/j.ajhg.2016.06.012

PubMed ID: 23092983

Title: Analysis of the chromosome X exome in patients with autism spectrum disorders identified novel candidate genes, including TMLHE.

PubMed ID: 23092983

DOI: 10.1038/tp.2012.102

PubMed ID: 28397838

Title: Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families.

PubMed ID: 28397838

DOI: 10.1038/mp.2017.60

Sequence Information:

  • Length: 1017
  • Mass: 111593
  • Checksum: 2E0839DB45B6C553
  • Sequence:
    • MVFSVRQCGH VGRTEEVLLT FKIFLVIICL HVVLVTSLEE DTDNSSLSPP PAKLSVVSFA 
PSSNGTPEVE TTSLNDVTLS LLPSNETEKT KITIVKTFNA SGVKPQRNIC NLSSICNDSA 
FFRGEIMFQY DKESTVPQNQ HITNGTLTGV LSLSELKRSE LNKTLQTLSE TYFIMCATAE 
AQSTLNCTFT IKLNNTMNAC AVIAALERVK IRPMEHCCCS VRIPCPSSPE ELEKLQCDLQ 
DPIVCLADHP RGPPFSSSQS IPVVPRATVL SQVPKATSFA EPPDYSPVTH NVPSPIGEIQ 
PLSPQPSAPI ASSPAIDMPP QSETISSPMP QTHVSGTPPP VKASFSSPTV SAPANVNTTS 
APPVQTDIVN TSSISDLENQ VLQMEKALSL GSLEPNLAGE MINQVSRLLH SPPDMLAPLA 
QRLLKVVDDI GLQLNFSNTT ISLTSPSLAL AVIRVNASSF NTTTFVAQDP ANLQVSLETQ 
APENSIGTIT LPSSLMNNLP AHDMELASRV QFNFFETPAL FQDPSLENLS LISYVISSSV 
ANLTVRNLTR NVTVTLKHIN PSQDELTVRC VFWDLGRNGG RGGWSDNGCS VKDRRLNETI 
CTCSHLTSFG VLLDLSRTSV LPAQMMALTF ITYIGCGLSS IFLSVTLVTY IAFEKIRRDY 
PSKILIQLCA ALLLLNLVFL LDSWIALYKM QGLCISVAVF LHYFLLVSFT WMGLEAFHMY 
LALVKVFNTY IRKYILKFCI VGWGVPAVVV TIILTISPDN YGLGSYGKFP NGSPDDFCWI 
NNNAVFYITV VGYFCVIFLL NVSMFIVVLV QLCRIKKKKQ LGAQRKTSIQ DLRSIAGLTF 
LLGITWGFAF FAWGPVNVTF MYLFAIFNTL QGFFIFIFYC VAKENVRKQW RRYLCCGKLR 
LAENSDWSKT ATNGLKKQTV NQGVSSSSNS LQSSSNSTNS TTLLVNNDCS VHASGNGNAS 
TERNGVSFSV QNGDVCLHDF TGKQHMFNEK EDSCNGKGRM ALRRTSKRGS LHFIEQM

Genular Protein ID: 2249611920

Symbol: A8K4P7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K4P7

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 5 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 1014
  • Mass: 111307
  • Checksum: 2EF97629B5F8AB9A
  • Sequence:
    • MVFSVRQCGH VGRTEEVLLT FKIFLVIICL HVVLVTSLEE DTDNSSLSPP PAKLSVVSFA 
PSSNEVETTS LNDVTLSLLP SNETEKTKIT IVKTFNASGV KPQRNICNLS SICNDSAFFR 
GEIMFQYDKE STVPQNQHIT NGTLTGVLSL SELKRSELNK TLQTLSETYF IMCATAEAQS 
TLNCTFTIKL NNTMNACAVI AALERVKIRP MEHCCCSVRI PCPSSPEELE KLQCDLQDPI 
VCLADHPRGP PFSSSQSIPV VPRATVLSQV PKATSFAEPP DYSPVTHNVP SPIGEIQPLS 
PQPSAPIASS PAIDMPPQSE TISSPMPQTH VSGTPPPVKA SFSSPTVSAP ANVNTTSAPP 
VQTDIVNTSS ISDLENQVLQ MEKALSLGSL EPNLAGEMIN QVSRLLHSPP DMLAPLAQRL 
LKVVDDIGLQ LNFSNTTISL TSPSLALAVI RVNASSFNTT TFVAQDPANL QVSLETQAPE 
NSIGTITLPS SLMNNLPAHD TELASRVQFN FFETPALFQD PSLENLSLIS YVISSSVANL 
TVRNLTRNVT VTLKHINPSQ DELTVRCVFW DLGRNGGRGG WSDNGCSVKD RRLNETICTC 
SHLTSFGVLL DLSRTSVLPA QMMALTFITY IGCGLSSIFL SVTLVTYIAF EKIRRDYPSK 
ILIQLCAALL LLNLVFLLDS WIALYKMQGL CISVAVFLHY FLLVSFTWMG LEAFHMYLAL 
VKVFNTYIRK YILKFCIVGW GVPAVVVTII LTISPDNYGL GSYGKFPNGS PDDFCWINNN 
AVFYITVVGY FCVIFLLNVS MFIVVLVQLC RIKKKKQLGA QRKTSIQDLR SIAGLTFLLG 
ITWGFAFFAW GPVNVTFMYL FAIFNTLQGF FIFIFYCVAK ENVRKQWRRY LCCGKLRLAE 
NSDWSKTATN GLKKQTVNQG VSSSSNSLQS SSNSTNSTTL LVNNDCSVHA SGNGNASTER 
NGVSFSVQNG DVCLHDFTGK QHMFNEKEDS CNGKGRMALR RTSKRGSLHF IEQM

Genular Protein ID: 183750449

Symbol: Q499H0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q499H0

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 5 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 2 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1003
  • Mass: 110073
  • Checksum: 47714A763278EA2D
  • Sequence:
    • MVFSVRQCGH VGRTEEVLLT FKIFLVIICL HVVLVTSLEE DTDNSSLSPP PAKLSVVSFA 
PSSNGTPEVE TTSLNDVTLS LLPSNETGVK PQRNICNLSS ICNDSAFFRG EIMFQYDKES 
TVPQNQHITN GTLTGVLSLS ELKRSELNKT LQTLSETYFI MCATAEAQST LNCTFTIKLN 
NTMNACAVIA ALERVKIRPM EHCCCSVRIP CPSSPEELEK LQCDLQDPIV CLADHPRGPP 
FSSSQSIPVV PRATVLSQVP KATSFAEPPD YSPVTHNVPS PIGEIQPLSP QPSAPIASSP 
AIDMPPQSET ISSPMPQTHV SGTPPPVKAS FSSPTVSAPA NVNTTSAPPV QTDIVNTSSI 
SDLENQVLQM EKALSLGSLE PNLAGEMINQ VSRLLHSPPD MLAPLAQRLL KVVDDIVLQL 
NFSNTTISLT SPSLALAVIR VNASSFNTTT FVAQDPANLQ VSLETQAPEN SIGTITLPSS 
LMNNLPAHDM ELASRVQFNF FETPALFQDP SLENLSLISY VISSSVANLT VRNLTRNVTV 
TLKHINPSQD ELTVRCVFWD LGRNGGRGGW SDNGCSVKDR RLNETICTCS HLTSFGVLLD 
LSRTSVLPAQ MMALTFITYI GCGLSSIFLS VTLVTYIAFE KIRRDYPSKI LIQLCAALLL 
LNLVFLLDSW IALYKMQGLC ISVAVFLHYF LLVSFTWMGL EAFHMYLALV KVFNTYIRKY 
ILKFCIVGWG VPAVVVTIIL TISPDNYGLG SYGKFPNGSP DDFCWINNNA VFYITVVGYF 
CVIFLLNVSM FIVVLVQLCR IKKKKQLGAQ RKTSIQDLRS IAGLTFLLGI TWGFAFFAWG 
PVNVTFMYLF AIFNTLQGFF IFIFYCVAKE NVRKQWRRYL CCGKLRLAEN SDWSKTATNG 
LKKQTVNQGV SSSSNSLQSS SNSTNSTTLL VNNDCSVHAS GNGNASTERN GVSFSVQNGD 
VCLHDFTGKQ HMFNEKEDSC NGKGRMALRR TSKRGSLHFI EQM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.