PLXNC1 | ENSG00000136040 | NCBI 10154

Details for: PLXNC1

Gene ID: 10154

Symbol: PLXNC1

Ensembl ID: ENSG00000136040

Description: plexin C1

Associated with

Axon guidance
(R-HSA-422475)
Developmental biology
(R-HSA-1266738)
Nervous system development
(R-HSA-9675108)
Other semaphorin interactions
(R-HSA-416700)
Semaphorin interactions
(R-HSA-373755)
Cell adhesion
(GO:0007155)
Cerebellar climbing fiber to purkinje cell synapse
(GO:0150053)
Membrane
(GO:0016020)
Negative regulation of cell adhesion
(GO:0007162)
Plasma membrane
(GO:0005886)
Positive regulation of axonogenesis
(GO:0050772)
Protein binding
(GO:0005515)
Regulation of cell migration
(GO:0030334)
Regulation of cell shape
(GO:0008360)
Regulation of gtpase activity
(GO:0043087)
Regulation of synapse pruning
(GO:1905806)
Semaphorin receptor activity
(GO:0017154)
Semaphorin receptor complex
(GO:0002116)
Signaling receptor binding
(GO:0005102)

Other Information

Proteins

Plexin-C1

Genular Protein ID: 194321986

Symbol: PLXC1_HUMAN

Name: Plexin-C1

UniProtKB Accession Codes:

O60486 Q59H25

Database IDs:

Citations:

PubMed ID: 9586637

Title: A poxvirus-encoded semaphorin induces cytokine production from monocytes and binds to a novel cellular semaphorin receptor, VESPR.

PubMed ID: 9586637

DOI: 10.1016/s1074-7613(00)80552-x

PubMed ID: 20727575

Title: Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1.

PubMed ID: 20727575

DOI: 10.1016/j.cell.2010.07.040

Sequence Information:

Length: 1568
Mass: 175742
Checksum: EA0CE5519BEF925D
Sequence:

MEVSRRKAPP RPPRPAAPLP LLAYLLALAA PGRGADEPVW RSEQAIGAIA ASQEDGVFVA 
SGSCLDQLDY SLEHSLSRLY RDQAGNCTEP VSLAPPARPR PGSSFSKLLL PYREGAAGLG 
GLLLTGWTFD RGACEVRPLG NLSRNSLRNG TEVVSCHPQG STAGVVYRAG RNNRWYLAVA 
ATYVLPEPET ASRCNPAASD HDTAIALKDT EGRSLATQEL GRLKLCEGAG SLHFVDAFLW 
NGSIYFPYYP YNYTSGAATG WPSMARIAQS TEVLFQGQAS LDCGHGHPDG RRLLLSSSLV 
EALDVWAGVF SAAAGEGQER RSPTTTALCL FRMSEIQARA KRVSWDFKTA ESHCKEGDQP 
ERVQPIASST LIHSDLTSVY GTVVMNRTVL FLGTGDGQLL KVILGENLTS NCPEVIYEIK 
EETPVFYKLV PDPVKNIYIY LTAGKEVRRI RVANCNKHKS CSECLTATDP HCGWCHSLQR 
CTFQGDCVHS ENLENWLDIS SGAKKCPKIQ IIRSSKEKTT VTMVGSFSPR HSKCMVKNVD 
SSRELCQNKS QPNRTCTCSI PTRATYKDVS VVNVMFSFGS WNLSDRFNFT NCSSLKECPA 
CVETGCAWCK SARRCIHPFT ACDPSDYERN QEQCPVAVEK TSGGGRPKEN KGNRTNQALQ 
VFYIKSIEPQ KVSTLGKSNV IVTGANFTRA SNITMILKGT STCDKDVIQV SHVLNDTHMK 
FSLPSSRKEM KDVCIQFDGG NCSSVGSLSY IALPHCSLIF PATTWISGGQ NITMMGRNFD 
VIDNLIISHE LKGNINVSEY CVATYCGFLA PSLKSSKVRT NVTVKLRVQD TYLDCGTLQY 
REDPRFTGYR VESEVDTELE VKIQKENDNF NISKKDIEIT LFHGENGQLN CSFENITRNQ 
DLTTILCKIK GIKTASTIAN SSKKVRVKLG NLELYVEQES VPSTWYFLIV LPVLLVIVIF 
AAVGVTRHKS KELSRKQSQQ LELLESELRK EIRDGFAELQ MDKLDVVDSF GTVPFLDYKH 
FALRTFFPES GGFTHIFTED MHNRDANDKN ESLTALDALI CNKSFLVTVI HTLEKQKNFS 
VKDRCLFASF LTIALQTKLV YLTSILEVLT RDLMEQCSNM QPKLMLRRTE SVVEKLLTNW 
MSVCLSGFLR ETVGEPFYLL VTTLNQKINK GPVDVITCKA LYTLNEDWLL WQVPEFSTVA 
LNVVFEKIPE NESADVCRNI SVNVLDCDTI GQAKEKIFQA FLSKNGSPYG LQLNEIGLEL 
QMGTRQKELL DIDSSSVILE DGITKLNTIG HYEISNGSTI KVFKKIANFT SDVEYSDDHC 
HLILPDSEAF QDVQGKRHRG KHKFKVKEMY LTKLLSTKVA IHSVLEKLFR SIWSLPNSRA 
PFAIKYFFDF LDAQAENKKI TDPDVVHIWK TNSLPLRFWV NILKNPQFVF DIKKTPHIDG 
CLSVIAQAFM DAFSLTEQQL GKEAPTNKLL YAKDIPTYKE EVKSYYKAIR DLPPLSSSEM 
EEFLTQESKK HENEFNEEVA LTEIYKYIVK YFDEILNKLE RERGLEEAQK QLLHVKVLFD 
EKKKCKWM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.