Details for: ATP6AP2

Gene ID: 10159

Symbol: ATP6AP2

Ensembl ID: ENSG00000182220

Description: ATPase H+ transporting accessory protein 2

Associated with

Other Information

Genular Protein ID: 2179136597

Symbol: RENR_HUMAN

Name: ATPase H(+)-transporting lysosomal accessory protein 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12045255

Title: Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin.

PubMed ID: 12045255

DOI: 10.1172/jci14276

PubMed ID: 10931946

Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.

PubMed ID: 10931946

DOI: 10.1073/pnas.160270997

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 9556572

Title: Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules.

PubMed ID: 9556572

DOI: 10.1074/jbc.273.18.10939

PubMed ID: 15746149

Title: A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor.

PubMed ID: 15746149

DOI: 10.1093/hmg/ddi094

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23595882

Title: Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS).

PubMed ID: 23595882

DOI: 10.1093/hmg/ddt180

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29127204

Title: Mutations in the X-linked ATP6AP2 cause a glycosylation disorder with autophagic defects.

PubMed ID: 29127204

DOI: 10.1084/jem.20170453

PubMed ID: 30374053

Title: TMEM9 promotes intestinal tumorigenesis through vacuolar-ATPase-activated Wnt/beta-catenin signalling.

PubMed ID: 30374053

DOI: 10.1038/s41556-018-0219-8

PubMed ID: 30985297

Title: ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.

PubMed ID: 30985297

DOI: 10.1172/jci79990

PubMed ID: 32276428

Title: Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection.

PubMed ID: 32276428

DOI: 10.3390/v12040414

PubMed ID: 21420935

Title: Structural analysis of the intracellular domain of (pro)renin receptor fused to maltose-binding protein.

PubMed ID: 21420935

DOI: 10.1016/j.bbrc.2011.03.074

PubMed ID: 33065002

Title: Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.

PubMed ID: 33065002

DOI: 10.1016/j.molcel.2020.09.029

Sequence Information:

  • Length: 350
  • Mass: 39008
  • Checksum: 84084A4ACE9C5DE8
  • Sequence:
  • MAVFVVLLAL VAGVLGNEFS ILKSPGSVVF RNGNWPIPGE RIPDVAALSM GFSVKEDLSW 
    PGLAVGNLFH RPRATVMVMV KGVNKLALPP GSVISYPLEN AVPFSLDSVA NSIHSLFSEE 
    TPVVLQLAPS EERVYMVGKA NSVFEDLSVT LRQLRNRLFQ ENSVLSSLPL NSLSRNNEVD 
    LLFLSELQVL HDISSLLSRH KHLAKDHSPD LYSLELAGLD EIGKRYGEDS EQFRDASKIL 
    VDALQKFADD MYSLYGGNAV VELVTVKSFD TSLIRKTRTI LEAKQAKNPA SPYNLAYKYN 
    FEYSVVFNMV LWIMIALALA VIITSYNIWN MDPGYDSIIY RMTNQKIRMD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.