Details for: LPAR6

Gene ID: 10161

Symbol: LPAR6

Ensembl ID: ENSG00000139679

Description: lysophosphatidic acid receptor 6

Associated with

Other Information

Genular Protein ID: 4214829660

Symbol: LPAR6_HUMAN

Name: Lysophosphatidic acid receptor 6

UniProtKB Accession Codes:

P43657 A4FTW9 B3KVF2 F2YGU4 O15133 Q3KPF5 Q53FA0 Q5VW44 Q7Z3S0 Q7Z3S6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 17 Ensembl 3 ExpressionAtlas 1 GO 5 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 4 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 3 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 7902321

Title: Complete genomic sequence of the human retinoblastoma susceptibility gene.

PubMed ID: 7902321

DOI: 10.1006/geno.1993.1368

PubMed ID: 8889552

Title: Intron 17 of the human retinoblastoma susceptibility gene encodes an actively transcribed G protein-coupled receptor gene.

PubMed ID: 8889552

DOI: 10.1101/gr.6.9.858

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11004484

Title: Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells.

PubMed ID: 11004484

DOI: 10.1016/s0167-4781(00)00094-4

PubMed ID: 18297070

Title: G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth.

PubMed ID: 18297070

DOI: 10.1038/ng.84

PubMed ID: 18692127

Title: Genome-wide linkage analysis of an autosomal recessive hypotrichosis identifies a novel P2RY5 mutation.

PubMed ID: 18692127

DOI: 10.1016/j.ygeno.2008.06.009

PubMed ID: 18461368

Title: Novel mutations in G protein-coupled receptor gene (P2RY5) in families with autosomal recessive hypotrichosis (LAH3).

PubMed ID: 18461368

DOI: 10.1007/s00439-008-0507-7

PubMed ID: 18297072

Title: Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair.

PubMed ID: 18297072

DOI: 10.1038/ng.100

PubMed ID: 19292720

Title: Mutations in the P2RY5 gene underlie autosomal recessive hypotrichosis in 13 Pakistani families.

PubMed ID: 19292720

DOI: 10.1111/j.1365-2133.2009.09046.x

PubMed ID: 21070332

Title: A novel mutation in LPAR6 causes autosomal recessive hypotrichosis of the scalp.

PubMed ID: 21070332

DOI: 10.1111/j.1365-2230.2010.03944.x

PubMed ID: 21426374

Title: Mutations in the LPAR6 and LIPH genes underlie autosomal recessive hypotrichosis/woolly hair in 17 consanguineous families from Pakistan.

PubMed ID: 21426374

DOI: 10.1111/j.1365-2230.2011.04014.x

PubMed ID: 28425126

Title: Novel sequence variants in the LIPH and LPAR6 genes underlies autosomal recessive woolly hair/hypotrichosis in consanguineous families.

PubMed ID: 28425126

DOI: 10.1111/cga.12226

PubMed ID: 36173926

Title: Cell-trafficking impairment in disease-associated LPA6 missense mutants and a potential pharmacoperone therapy for autosomal recessive woolly hair/hypotrichosis.

PubMed ID: 36173926

DOI: 10.1093/hmg/ddac244

Sequence Information:

  • Length: 344
  • Mass: 39392
  • Checksum: 699212F3C1249433
  • Sequence:
    • MVSVNSSHCF YNDSFKYTLY GCMFSMVFVL GLISNCVAIY IFICVLKVRN ETTTYMINLA 
MSDLLFVFTL PFRIFYFTTR NWPFGDLLCK ISVMLFYTNM YGSILFLTCI SVDRFLAIVY 
PFKSKTLRTK RNAKIVCTGV WLTVIGGSAP AVFVQSTHSQ GNNASEACFE NFPEATWKTY 
LSRIVIFIEI VGFFIPLILN VTCSSMVLKT LTKPVTLSRS KINKTKVLKM IFVHLIIFCF 
CFVPYNINLI LYSLVRTQTF VNCSVVAAVR TMYPITLCIA VSNCCFDPIV YYFTSDTIQN 
SIKMKNWSVR RSDFRFSEVH GAENFIQHNL QTLKSKIFDN ESAA

Genular Protein ID: 4251917588

Symbol: B3KVQ5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KVQ5

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 3 Pfam 1 PharmGKB 1 RefSeq 3 RuleBase 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 344
  • Mass: 39365
  • Checksum: F82B020D21CA9AD3
  • Sequence:
    • MVSVNSSHCF YNDSFKYTLY GCMFSMVFVL GLISNCVAIY IFICVLKVRN ETTTYMINLA 
MSDLLFVFTL PFRIFYFTTR NWPFGDLLCK ISVMLFYTNM YGSILFLTCI SVDRFLAIVY 
PFKSKTLRTK RNAKIVCTGV WLTVIGGSAP AVFVQSTHSQ GNNASEACFE NFPEATWKTY 
LSRIVIFIEI VGFFIPLILN VTCSSMVLKT LTKPVTLSRS KINKTKVLKM IFVHLIIFCF 
CFVPYSINLI LYSLVRTQTF VNCSVVAAVR TMYPITLCIA VSNCCFDPIV YYFTSDTIQN 
SIKMKNWSVR RSDFRFSEVH GAENFIQHNL QTLKSKIFDN ESAA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.