LPCAT3 | ENSG00000111684 | NCBI 10162

Details for: LPCAT3

Gene ID: 10162

Symbol: LPCAT3

Ensembl ID: ENSG00000111684

Description: lysophosphatidylcholine acyltransferase 3

Associated with

Acyl chain remodelling of pc
(R-HSA-1482788)
Acyl chain remodelling of pe
(R-HSA-1482839)
Acyl chain remodelling of ps
(R-HSA-1482801)
Glycerophospholipid biosynthesis
(R-HSA-1483206)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Phospholipid metabolism
(R-HSA-1483257)
1-acylglycerol-3-phosphate o-acyltransferase activity
(GO:0003841)
1-acylglycerophosphocholine o-acyltransferase activity
(GO:0047184)
1-acylglycerophosphoethanolamine o-acyltransferase activity
(GO:0106262)
1-acylglycerophosphoserine o-acyltransferase activity
(GO:0106263)
2-acylglycerol-3-phosphate o-acyltransferase activity
(GO:0047144)
Chylomicron assembly
(GO:0034378)
Endoplasmic reticulum membrane
(GO:0005789)
Endoplasmic reticulum membrane organization
(GO:0090158)
Intestinal stem cell homeostasis
(GO:0036335)
Lipid modification
(GO:0030258)
Lysophospholipid acyltransferase activity
(GO:0071617)
Membrane
(GO:0016020)
Negative regulation of inflammatory response
(GO:0050728)
Negative regulation of response to endoplasmic reticulum stress
(GO:1903573)
Phosphatidylcholine acyl-chain remodeling
(GO:0036151)
Phosphatidylcholine biosynthetic process
(GO:0006656)
Phosphatidylethanolamine acyl-chain remodeling
(GO:0036152)
Phosphatidylserine acyl-chain remodeling
(GO:0036150)
Positive regulation of intestinal cholesterol absorption
(GO:0045797)
Positive regulation of triglyceride transport
(GO:1905885)
Regulation of cholesterol biosynthetic process
(GO:0045540)
Very-low-density lipoprotein particle assembly
(GO:0034379)

Other Information

Proteins

Lysophospholipid acyltransferase 5

Genular Protein ID: 1569436361

Symbol: MBOA5_HUMAN

Name: Lysophospholipid acyltransferase 5

UniProtKB Accession Codes:

Q6P1A2 B2RDH0 B7Z3N3 Q7KZS1 Q92980 Q9BW40

Database IDs:

Citations:

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9074930

Title: Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination.

PubMed ID: 9074930

DOI: 10.1101/gr.7.3.268

PubMed ID: 18782225

Title: Member of the membrane-bound O-acyltransferase (MBOAT) family encodes a lysophospholipid acyltransferase with broad substrate specificity.

PubMed ID: 18782225

DOI: 10.1111/j.1365-2443.2008.01212.x

PubMed ID: 18195019

Title: Identification and characterization of a major liver lysophosphatidylcholine acyltransferase.

PubMed ID: 18195019

DOI: 10.1074/jbc.m710422200

PubMed ID: 18772128

Title: Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils.

PubMed ID: 18772128

DOI: 10.1074/jbc.m806194200

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

Sequence Information:

Length: 487
Mass: 56035
Checksum: 429258B54585B4A7
Sequence:

MASSAEGDEG TVVALAGVLQ SGFQELSLNK LATSLGASEQ ALRLIISIFL GYPFALFYRH 
YLFYKETYLI HLFHTFTGLS IAYFNFGNQL YHSLLCIVLQ FLILRLMGRT ITAVLTTFCF 
QMAYLLAGYY YTATGNYDIK WTMPHCVLTL KLIGLAVDYF DGGKDQNSLS SEQQKYAIRG 
VPSLLEVAGF SYFYGAFLVG PQFSMNHYMK LVQGELIDIP GKIPNSIIPA LKRLSLGLFY 
LVGYTLLSPH ITEDYLLTED YDNHPFWFRC MYMLIWGKFV LYKYVTCWLV TEGVCILTGL 
GFNGFEEKGK AKWDACANMK VWLFETNPRF TGTIASFNIN TNAWVARYIF KRLKFLGNKE 
LSQGLSLLFL ALWHGLHSGY LVCFQMEFLI VIVERQAARL IQESPTLSKL AAITVLQPFY 
YLVQQTIHWL FMGYSMTAFC LFTWDKWLKV YKSIYFLGHI FFLSLLFILP YIHKAMVPRK 
EKLKKME

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: LPCAT3

Associated with

Other Information

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The finished DNA sequence of human chromosome 12. PubMed ID: 16541075

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination. PubMed ID: 9074930

Member of the membrane-bound O-acyltransferase (MBOAT) family encodes a lysophospholipid acyltransferase with broad substrate specificity. PubMed ID: 18782225

Identification and characterization of a major liver lysophosphatidylcholine acyltransferase. PubMed ID: 18195019

Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils. PubMed ID: 18772128

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712