CHST4 | ENSG00000140835 | NCBI 10164

Details for: CHST4

Gene ID: 10164

Symbol: CHST4

Ensembl ID: ENSG00000140835

Description: carbohydrate sulfotransferase 4

Associated with

Metabolism of proteins
(R-HSA-392499)
O-linked glycosylation
(R-HSA-5173105)
O-linked glycosylation of mucins
(R-HSA-913709)
Post-translational protein modification
(R-HSA-597592)
Carbohydrate metabolic process
(GO:0005975)
Cell-cell signaling
(GO:0007267)
Cell adhesion
(GO:0007155)
Golgi membrane
(GO:0000139)
Immune response
(GO:0006955)
Inflammatory response
(GO:0006954)
N-acetylglucosamine 6-o-sulfotransferase activity
(GO:0001517)
N-acetylglucosamine metabolic process
(GO:0006044)
O-glycan processing
(GO:0016266)
Positive regulation of leukocyte tethering or rolling
(GO:1903238)
Protein sulfation
(GO:0006477)
Sulfotransferase activity
(GO:0008146)
Sulfur compound metabolic process
(GO:0006790)
Trans-golgi network
(GO:0005802)

Other Information

Proteins

Carbohydrate sulfotransferase 4

Genular Protein ID: 152247521

Symbol: CHST4_HUMAN

Name: Carbohydrate sulfotransferase 4

UniProtKB Accession Codes:

Q8NCG5 Q8IV46 Q9Y5R3

Database IDs:

Citations:

PubMed ID: 10330415

Title: Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin.

PubMed ID: 10330415

DOI: 10.1083/jcb.145.4.899

PubMed ID: 11439191

Title: Novel sulfated lymphocyte homing receptors and their control by a Core1 extension beta 1,3-N-acetylglucosaminyltransferase.

PubMed ID: 11439191

DOI: 10.1016/s0092-8674(01)00394-4

PubMed ID: 11181564

Title: Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family.

PubMed ID: 11181564

DOI: 10.1093/glycob/11.1.75

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11310842

Title: CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin.

PubMed ID: 11310842

PubMed ID: 12107080

Title: Ectopic expression of a GlcNAc 6-O-sulfotransferase, GlcNAc6ST-2, in colonic mucinous adenocarcinoma.

PubMed ID: 12107080

DOI: 10.1093/glycob/12.6.379

PubMed ID: 11726653

Title: Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression.

PubMed ID: 11726653

DOI: 10.1074/jbc.m106587200

PubMed ID: 12855678

Title: Golgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesis.

PubMed ID: 12855678

DOI: 10.1074/jbc.m304928200

PubMed ID: 15220337

Title: The stem region of the sulfotransferase GlcNAc6ST-1 is a determinant of substrate specificity.

PubMed ID: 15220337

DOI: 10.1074/jbc.m405709200

Sequence Information:

Length: 386
Mass: 45134
Checksum: 0C3BB4022417143A
Sequence:

MLLPKKMKLL LFLVSQMAIL ALFFHMYSHN ISSLSMKAQP ERMHVLVLSS WRSGSSFVGQ 
LFGQHPDVFY LMEPAWHVWM TFKQSTAWML HMAVRDLIRA VFLCDMSVFD AYMEPGPRRQ 
SSLFQWENSR ALCSAPACDI IPQDEIIPRA HCRLLCSQQP FEVVEKACRS YSHVVLKEVR 
FFNLQSLYPL LKDPSLNLHI VHLVRDPRAV FRSRERTKGD LMIDSRIVMG QHEQKLKKED 
QPYYVMQVIC QSQLEIYKTI QSLPKALQER YLLVRYEDLA RAPVAQTSRM YEFVGLEFLP 
HLQTWVHNIT RGKGMGDHAF HTNARDALNV SQAWRWSLPY EKVSRLQKAC GDAMNLLGYR 
HVRSEQEQRN LLLDLLSTWT VPEQIH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CHST4

Associated with

Other Information

Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin. PubMed ID: 10330415

Novel sulfated lymphocyte homing receptors and their control by a Core1 extension beta 1,3-N-acetylglucosaminyltransferase. PubMed ID: 11439191

Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family. PubMed ID: 11181564

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin. PubMed ID: 11310842

Ectopic expression of a GlcNAc 6-O-sulfotransferase, GlcNAc6ST-2, in colonic mucinous adenocarcinoma. PubMed ID: 12107080

Specificities of N-acetylglucosamine-6-O-sulfotransferases in relation to L-selectin ligand synthesis and tumor-associated enzyme expression. PubMed ID: 11726653

Golgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesis. PubMed ID: 12855678

The stem region of the sulfotransferase GlcNAc6ST-1 is a determinant of substrate specificity. PubMed ID: 15220337