SLC25A13 | ENSG00000004864 | NCBI 10165

Details for: SLC25A13

Gene ID: 10165

Symbol: SLC25A13

Ensembl ID: ENSG00000004864

Description: solute carrier family 25 member 13

Associated with

Aspartate and asparagine metabolism
(R-HSA-8963693)
Glucose metabolism
(R-HSA-70326)
Metabolism
(R-HSA-1430728)
Metabolism of amino acids and derivatives
(R-HSA-71291)
Metabolism of carbohydrates
(R-HSA-71387)
Mitochondrial protein import
(R-HSA-1268020)
Protein localization
(R-HSA-9609507)
3-sulfino-l-alanine: proton, glutamate antiporter activity
(GO:0000514)
Acidic amino acid transmembrane transporter activity
(GO:0015172)
Aspartate:glutamate, proton antiporter activity
(GO:0000515)
Aspartate family amino acid metabolic process
(GO:0009066)
Aspartate transmembrane transport
(GO:0015810)
Atp biosynthetic process
(GO:0006754)
Calcium ion binding
(GO:0005509)
Cellular respiration
(GO:0045333)
Gluconeogenesis
(GO:0006094)
Identical protein binding
(GO:0042802)
L-aspartate transmembrane transport
(GO:0070778)
L-aspartate transmembrane transporter activity
(GO:0015183)
L-glutamate transmembrane transport
(GO:0015813)
L-glutamate transmembrane transporter activity
(GO:0005313)
Malate-aspartate shuttle
(GO:0043490)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial transport
(GO:0006839)
Mitochondrion
(GO:0005739)
Modified amino acid transport
(GO:0072337)
Neutral amino acid transport
(GO:0015804)
Plasma membrane
(GO:0005886)
Proton transmembrane transport
(GO:1902600)
Response to calcium ion
(GO:0051592)

Other Information

Proteins

Calcium-binding mitochondrial carrier protein Aralar2

Genular Protein ID: 295355015

Symbol: S2513_HUMAN

Name: Calcium-binding mitochondrial carrier protein Aralar2

UniProtKB Accession Codes:

Q9UJS0 O14566 O14575 Q546F9 Q9NZW1 Q9UNI7

Database IDs:

Citations:

PubMed ID: 10369257

Title: The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein.

PubMed ID: 10369257

DOI: 10.1038/9667

PubMed ID: 10642534

Title: Characterization of a second member of the subfamily of calcium-binding mitochondrial carriers expressed in human non-excitable tissues.

PubMed ID: 10642534

DOI: 10.1042/0264-6021:3450725

PubMed ID: 11566871

Title: Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria.

PubMed ID: 11566871

DOI: 10.1093/emboj/20.18.5060

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10610724

Title: Genomic structure of the adult-onset type II citrullinemia gene, SLC25A13, and cloning and expression of its mouse homologue.

PubMed ID: 10610724

DOI: 10.1006/geno.1999.6006

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 11793471

Title: Screening of SLC25A13 mutations in early and late onset patients with citrin deficiency and in the Japanese population: identification of two novel mutations and establishment of multiple DNA diagnosis methods for nine mutations.

PubMed ID: 11793471

DOI: 10.1002/humu.10022

PubMed ID: 25410934

Title: Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers.

PubMed ID: 25410934

DOI: 10.1038/ncomms6491

Sequence Information:

Length: 675
Mass: 74176
Checksum: AD07EDBC6C68989B
Sequence:

MAAAKVALTK RADPAELRTI FLKYASIEKN GEFFMSPNDF VTRYLNIFGE SQPNPKTVEL 
LSGVVDQTKD GLISFQEFVA FESVLCAPDA LFMVAFQLFD KAGKGEVTFE DVKQVFGQTT 
IHQHIPFNWD SEFVQLHFGK ERKRHLTYAE FTQFLLEIQL EHAKQAFVQR DNARTGRVTA 
IDFRDIMVTI RPHVLTPFVE ECLVAAAGGT TSHQVSFSYF NGFNSLLNNM ELIRKIYSTL 
AGTRKDVEVT KEEFVLAAQK FGQVTPMEVD ILFQLADLYE PRGRMTLADI ERIAPLEEGT 
LPFNLAEAQR QKASGDSARP VLLQVAESAY RFGLGSVAGA VGATAVYPID LVKTRMQNQR 
STGSFVGELM YKNSFDCFKK VLRYEGFFGL YRGLLPQLLG VAPEKAIKLT VNDFVRDKFM 
HKDGSVPLAA EILAGGCAGG SQVIFTNPLE IVKIRLQVAG EITTGPRVSA LSVVRDLGFF 
GIYKGAKACF LRDIPFSAIY FPCYAHVKAS FANEDGQVSP GSLLLAGAIA GMPAASLVTP 
ADVIKTRLQV AARAGQTTYS GVIDCFRKIL REEGPKALWK GAGARVFRSS PQFGVTLLTY 
ELLQRWFYID FGGVKPMGSE PVPKSRINLP APNPDHVGGY KLAVATFAGI ENKFGLYLPL 
FKPSVSTSKA IGGGP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SLC25A13

Associated with

Other Information

The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein. PubMed ID: 10369257

Characterization of a second member of the subfamily of calcium-binding mitochondrial carriers expressed in human non-excitable tissues. PubMed ID: 10642534

Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria. PubMed ID: 11566871

The DNA sequence of human chromosome 7. PubMed ID: 12853948

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Genomic structure of the adult-onset type II citrullinemia gene, SLC25A13, and cloning and expression of its mouse homologue. PubMed ID: 10610724

Initial characterization of the human central proteome. PubMed ID: 21269460

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Screening of SLC25A13 mutations in early and late onset patients with citrin deficiency and in the Japanese population: identification of two novel mutations and establishment of multiple DNA diagnosis methods for nine mutations. PubMed ID: 11793471

Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers. PubMed ID: 25410934