Details for: SLC25A15

Gene ID: 10166

Symbol: SLC25A15

Ensembl ID: ENSG00000102743

Description: solute carrier family 25 member 15

Associated with

Other Information

Genular Protein ID: 4181702758

Symbol: ORNT1_HUMAN

Name: Mitochondrial ornithine transporter 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10369256

Title: Hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome is caused by mutations in a gene encoding a mitochondrial ornithine transporter.

PubMed ID: 10369256

DOI: 10.1038/9658

PubMed ID: 12807890

Title: The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms.

PubMed ID: 12807890

DOI: 10.1074/jbc.m302317200

PubMed ID: 15498874

Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.

PubMed ID: 15498874

DOI: 10.1073/pnas.0404089101

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22262851

Title: Substrate specificity of the two mitochondrial ornithine carriers can be swapped by single mutation in substrate binding site.

PubMed ID: 22262851

DOI: 10.1074/jbc.m111.324855

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 10805333

Title: Three novel mutations (G27E, insAAC, R179X) in the ORNT1 gene of Japanese patients with hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome.

PubMed ID: 10805333

DOI: 10.1002/1531-8249(200005)47:5<625::aid-ana10>3.3.co;2-h

PubMed ID: 11668643

Title: Seven novel mutations in the ORNT1 gene (SLC25A15) in patients with hyperornithinemia, hyperammonemia, and homocitrullinuria syndrome.

PubMed ID: 11668643

DOI: 10.1002/humu.1221

PubMed ID: 11552031

Title: Clinical and molecular findings in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.

PubMed ID: 11552031

DOI: 10.1212/wnl.57.5.911

PubMed ID: 11814739

Title: A novel mutation, P126R, in a Japanese patient with HHH syndrome.

PubMed ID: 11814739

DOI: 10.1016/s0887-8994(01)00335-6

PubMed ID: 16601889

Title: HHH syndrome (hyperornithinaemia, hyperammonaemia, homocitrullinuria), with fulminant hepatitis-like presentation.

PubMed ID: 16601889

DOI: 10.1007/s10545-006-0120-7

PubMed ID: 19242930

Title: Identification of novel mutations in the SLC25A15 gene in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome: a clinical, molecular, and functional study.

PubMed ID: 19242930

DOI: 10.1002/humu.20930

PubMed ID: 24721342

Title: A novel mutation in the SLC25A15 gene in a Turkish patient with HHH syndrome: functional analysis of the mutant protein.

PubMed ID: 24721342

DOI: 10.1016/j.ymgme.2014.03.002

Sequence Information:

  • Length: 301
  • Mass: 32736
  • Checksum: 34436A15B105DC53
  • Sequence:
  • MKSNPAIQAA IDLTAGAAGG TACVLTGQPF DTMKVKMQTF PDLYRGLTDC CLKTYSQVGF 
    RGFYKGTSPA LIANIAENSV LFMCYGFCQQ VVRKVAGLDK QAKLSDLQNA AAGSFASAFA 
    ALVLCPTELV KCRLQTMYEM ETSGKIAKSQ NTVWSVIKSI LRKDGPLGFY HGLSSTLLRE 
    VPGYFFFFGG YELSRSFFAS GRSKDELGPV PLMLSGGVGG ICLWLAVYPV DCIKSRIQVL 
    SMSGKQAGFI RTFINVVKNE GITALYSGLK PTMIRAFPAN GALFLAYEYS RKLMMNQLEA 
    Y

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.