DHRS9 | ENSG00000073737 | NCBI 10170

Details for: DHRS9

Gene ID: 10170

Symbol: DHRS9

Ensembl ID: ENSG00000073737

Description: dehydrogenase/reductase 9

Associated with

Ra biosynthesis pathway
(R-HSA-5365859)
Sensory perception
(R-HSA-9709957)
Signaling by nuclear receptors
(R-HSA-9006931)
Signaling by retinoic acid
(R-HSA-5362517)
Signal transduction
(R-HSA-162582)
The canonical retinoid cycle in rods (twilight vision)
(R-HSA-2453902)
Visual phototransduction
(R-HSA-2187338)
9-cis-retinoic acid biosynthetic process
(GO:0042904)
Alcohol dehydrogenase (nad+) activity
(GO:0004022)
Androgen metabolic process
(GO:0008209)
Androstan-3-alpha,17-beta-diol dehydrogenase activity
(GO:0047044)
Androsterone dehydrogenase activity
(GO:0047023)
Endoplasmic reticulum membrane
(GO:0005789)
Epithelial cell differentiation
(GO:0030855)
Intracellular membrane-bounded organelle
(GO:0043231)
Nad-retinol dehydrogenase activity
(GO:0004745)
Progesterone metabolic process
(GO:0042448)
Racemase and epimerase activity
(GO:0016854)
Retinol metabolic process
(GO:0042572)
Steroid metabolic process
(GO:0008202)
Testosterone dehydrogenase (nad+) activity
(GO:0047035)

Other Information

Proteins

Dehydrogenase/reductase SDR family member 9

Genular Protein ID: 3814217908

Symbol: DHRS9_HUMAN

Name: Dehydrogenase/reductase SDR family member 9

UniProtKB Accession Codes:

Q9BPW9 B7Z416 D3DPC1 Q5RKX1 Q9NRA9 Q9NRB0

Database IDs:

Citations:

PubMed ID: 11294878

Title: Characterization of a novel type of human microsomal 3alpha-hydroxysteroid dehydrogenase. Unique tissue distribution and catalytic properties.

PubMed ID: 11294878

DOI: 10.1074/jbc.m102076200

PubMed ID: 11304534

Title: Characterization of a novel airway epithelial cell-specific short chain alcohol dehydrogenase/reductase gene whose expression is up-regulated by retinoids and is involved in the metabolism of retinol.

PubMed ID: 11304534

DOI: 10.1074/jbc.m100332200

PubMed ID: 12618084

Title: Expression pattern and biochemical characteristics of a major epidermal retinol dehydrogenase.

PubMed ID: 12618084

DOI: 10.1016/s1096-7192(02)00226-3

PubMed ID: 10800688

Title: Short-chain dehydrogenases/reductases in retina.

PubMed ID: 10800688

DOI: 10.1016/s0076-6879(00)16736-9

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19027726

Title: The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.

PubMed ID: 19027726

DOI: 10.1016/j.cbi.2008.10.040

PubMed ID: 29541409

Title: Inhibition of dihydrotestosterone synthesis in prostate cancer by combined frontdoor and backdoor pathway blockade.

PubMed ID: 29541409

DOI: 10.18632/oncotarget.24107

Sequence Information:

Length: 319
Mass: 35227
Checksum: DEE8CD65E5C25C6F
Sequence:

MLFWVLGLLI LCGFLWTRKG KLKIEDITDK YIFITGCDSG FGNLAARTFD KKGFHVIAAC 
LTESGSTALK AETSERLRTV LLDVTDPENV KRTAQWVKNQ VGEKGLWGLI NNAGVPGVLA 
PTDWLTLEDY REPIEVNLFG LISVTLNMLP LVKKAQGRVI NVSSVGGRLA IVGGGYTPSK 
YAVEGFNDSL RRDMKAFGVH VSCIEPGLFK TNLADPVKVI EKKLAIWEQL SPDIKQQYGE 
GYIEKSLDKL KGNKSYVNMD LSPVVECMDH ALTSLFPKTH YAAGKDAKIF WIPLSHMPAA 
LQDFLLLKQK AELANPKAV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: DHRS9

Associated with

Other Information

Characterization of a novel type of human microsomal 3alpha-hydroxysteroid dehydrogenase. Unique tissue distribution and catalytic properties. PubMed ID: 11294878

Characterization of a novel airway epithelial cell-specific short chain alcohol dehydrogenase/reductase gene whose expression is up-regulated by retinoids and is involved in the metabolism of retinol. PubMed ID: 11304534

Expression pattern and biochemical characteristics of a major epidermal retinol dehydrogenase. PubMed ID: 12618084

Short-chain dehydrogenases/reductases in retina. PubMed ID: 10800688

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Generation and annotation of the DNA sequences of human chromosomes 2 and 4. PubMed ID: 15815621

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. PubMed ID: 19027726

Inhibition of dihydrotestosterone synthesis in prostate cancer by combined frontdoor and backdoor pathway blockade. PubMed ID: 29541409