Details for: RCL1

Gene ID: 10171

Symbol: RCL1

Ensembl ID: ENSG00000120158

Description: RNA terminal phosphate cyclase like 1

Associated with

  • Major pathway of rrna processing in the nucleolus and cytosol
    (R-HSA-6791226)
  • Metabolism of rna
    (R-HSA-8953854)
  • Rrna modification in the nucleus and cytosol
    (R-HSA-6790901)
  • Rrna processing
    (R-HSA-72312)
  • Rrna processing in the nucleus and cytosol
    (R-HSA-8868773)
  • Biological_process
    (GO:0008150)
  • Endonucleolytic cleavage in 5'-ets of tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna)
    (GO:0000480)
  • Endonucleolytic cleavage in its1 to separate ssu-rrna from 5.8s rrna and lsu-rrna from tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna)
    (GO:0000447)
  • Endonucleolytic cleavage of tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna)
    (GO:0000479)
  • Nucleolus
    (GO:0005730)
  • Nucleoplasm
    (GO:0005654)
  • Protein binding
    (GO:0005515)
  • Ribosomal small subunit biogenesis
    (GO:0042274)
  • Rna endonuclease activity
    (GO:0004521)
  • Small-subunit processome
    (GO:0032040)

Other Information

Genular Protein ID: 3888142519

Symbol: RCL1_HUMAN

Name: RNA 3'-terminal phosphate cyclase-like protein

UniProtKB Accession Codes:

Q9Y2P8 D3DRI2 Q5VYW9 Q5VZU1 Q9H9D0 Q9NY00 Q9P044

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EMDB 3 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 8 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 3 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 6 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10790377

Title: Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis.

PubMed ID: 10790377

DOI: 10.1093/emboj/19.9.2115

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11042152

Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.

PubMed ID: 11042152

DOI: 10.1101/gr.140200

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 34516797

Title: Nucleolar maturation of the human small subunit processome.

PubMed ID: 34516797

DOI: 10.1126/science.abj5338

Sequence Information:

  • Length: 373
  • Mass: 40843
  • Checksum: 533FAE8420AF93CB
  • Sequence:
    • MATQAHSLSY AGCNFLRQRL VLSTLSGRPV KIRKIRARDD NPGLRDFEAS FIRLLDKITN 
GSRIEINQTG TTLYYQPGLL YGGSVEHDCS VLRGIGYYLE SLLCLAPFMK HPLKIVLRGV 
TNDQVDPSVD VLKATALPLL KQFGIDGESF ELKIVRRGMP PGGGGEVVFS CPVRKVLKPI 
QLTDPGKIKR IRGMAYSVRV SPQMANRIVD SARSILNKFI PDIYIYTDHM KGVNSGKSPG 
FGLSLVAETT SGTFLSAELA SNPQGQGAAV LPEDLGRNCA RLLLEEIYRG GCVDSTNQSL 
ALLLMTLGQQ DVSKVLLGPL SPYTIEFLRH LKSFFQIMFK IETKPCGEEL KGGDKVLMTC 
VGIGFSNLSK TLK

Genular Protein ID: 2794701892

Symbol: Q5VZU3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5VZU3 A0A087X1L9

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 2 SMR 1 SUPFAM 1 UCSC 2 VEuPathDB 1

Citations:

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 215
  • Mass: 23252
  • Checksum: 00BA4FC854282569
  • Sequence:
    • MPPGGGGEVV FSCPVRKVLK PIQLTDPGKI KRIRGMAYSV RVSPQMANRI VDSARSILNK 
FIPDIYIYTD HMKGVNSGKS PGFGLSLVAE TTSGTFLSAE LASNPQGQGA AVLPEDLGRN 
CARLLLEEIY RGGCVDSTNQ SLALLLMTLG QQDVSKVLLG PLSPYTIEFL RHLKSFFQIM 
FKIETKPCGE ELKGGDKVLM TCVGIGFSNL SKTLK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.