RBM5 | ENSG00000003756 | NCBI 10181

Details for: RBM5

Gene ID: 10181

Symbol: RBM5

Ensembl ID: ENSG00000003756

Description: RNA binding motif protein 5

Associated with

Metabolism of rna
(R-HSA-8953854)
Mrna splicing
(R-HSA-72172)
Mrna splicing - major pathway
(R-HSA-72163)
Processing of capped intron-containing pre-mrna
(R-HSA-72203)
Apoptotic process
(GO:0006915)
Dna binding
(GO:0003677)
Metal ion binding
(GO:0046872)
Mrna binding
(GO:0003729)
Mrna splicing, via spliceosome
(GO:0000398)
Negative regulation of cell population proliferation
(GO:0008285)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of apoptotic process
(GO:0043065)
Protein binding
(GO:0005515)
Regulation of alternative mrna splicing, via spliceosome
(GO:0000381)
Rna binding
(GO:0003723)
Rna processing
(GO:0006396)
Spliceosomal complex
(GO:0005681)
Spliceosomal complex assembly
(GO:0000245)

Other Information

Proteins

RNA-binding protein 5

Genular Protein ID: 1888258426

Symbol: RBM5_HUMAN

Name: RNA-binding protein 5

UniProtKB Accession Codes:

P52756 B2RA45 B4DM16 B4DMF9 B4DZ63 Q93021 Q9BU14 Q9HDA6 Q9UKY8 Q9UL24

Database IDs:

Citations:

PubMed ID: 10486216

Title: An evolutionary rearrangement of the Xp11.3-11.23 region in 3p21.3, a region frequently deleted in a variety of cancers.

PubMed ID: 10486216

DOI: 10.1006/geno.1999.5878

PubMed ID: 10497265

Title: Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells.

PubMed ID: 10497265

DOI: 10.1093/nar/27.20.4008

PubMed ID: 10949932

Title: LUCA-15-encoded sequence variants regulate CD95-mediated apoptosis.

PubMed ID: 10949932

DOI: 10.1038/sj.onc.1203720

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10508479

Title: Antigens recognized by autologous antibody in patients with renal-cell carcinoma.

PubMed ID: 10508479

DOI: 10.1002/(sici)1097-0215(19991112)83:4<456::aid-ijc4>3.0.co;2-5

PubMed ID: 12207175

Title: Candidate tumour suppressor LUCA-15 can regulate multiple apoptotic pathways.

PubMed ID: 12207175

DOI: 10.1023/a:1020083008017

PubMed ID: 12581154

Title: Simultaneous acceleration of the cell cycle and suppression of apoptosis by splice variant delta-6 of the candidate tumour suppressor LUCA-15/RBM5.

PubMed ID: 12581154

DOI: 10.1046/j.1365-2443.2003.00619.x

PubMed ID: 15192330

Title: LUCA-15/RBM5, a putative tumour suppressor, enhances multiple receptor-initiated death signals.

PubMed ID: 15192330

DOI: 10.1023/b:appt.0000031455.79352.57

PubMed ID: 16585163

Title: 3p21.3 tumor suppressor gene H37/Luca15/RBM5 inhibits growth of human lung cancer cells through cell cycle arrest and apoptosis.

PubMed ID: 16585163

DOI: 10.1158/0008-5472.can-05-1667

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17332742

Title: Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.

PubMed ID: 17332742

DOI: 10.1038/sj.emboj.7601631

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18851835

Title: RBM5/Luca-15/H37 regulates Fas alternative splice site pairing after exon definition.

PubMed ID: 18851835

DOI: 10.1016/j.molcel.2008.08.008

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18840686

Title: Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5.

PubMed ID: 18840686

DOI: 10.1073/pnas.0805569105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

Length: 815
Mass: 92154
Checksum: AA79962D13405479
Sequence:

MGSDKRVSRT ERSGRYGSII DRDDRDERES RSRRRDSDYK RSSDDRRGDR YDDYRDYDSP 
ERERERRNSD RSEDGYHSDG DYGEHDYRHD ISDERESKTI MLRGLPITIT ESDIREMMES 
FEGPQPADVR LMKRKTGVSR GFAFVEFYHL QDATSWMEAN QKKLVIQGKH IAMHYSNPRP 
KFEDWLCNKC CLNNFRKRLK CFRCGADKFD SEQEVPPGTT ESVQSVDYYC DTIILRNIAP 
HTVVDSIMTA LSPYASLAVN NIRLIKDKQT QQNRGFAFVQ LSSAMDASQL LQILQSLHPP 
LKIDGKTIGV DFAKSARKDL VLSDGNRVSA FSVASTAIAA AQWSSTQSQS GEGGSVDYSY 
LQPGQDGYAQ YAQYSQDYQQ FYQQQAGGLE SDASSASGTA VTTTSAAVVS QSPQLYNQTS 
NPPGSPTEEA QPSTSTSTQA PAASPTGVVP GTKYAVPDTS TYQYDESSGY YYDPTTGLYY 
DPNSQYYYNS LTQQYLYWDG EKETYVPAAE SSSHQQSGLP PAKEGKEKKE KPKSKTAQQI 
AKDMERWAKS LNKQKENFKN SFQPVNSLRE EERRESAAAD AGFALFEKKG ALAERQQLIP 
ELVRNGDEEN PLKRGLVAAY SGDSDNEEEL VERLESEEEK LADWKKMACL LCRRQFPNKD 
ALVRHQQLSD LHKQNMDIYR RSRLSEQELE ALELREREMK YRDRAAERRE KYGIPEPPEP 
KRKKQFDAGT VNYEQPTKDG IDHSNIGNKM LQAMGWREGS GLGRKCQGIT APIEAQVRLK 
GAGLGAKGSA YGLSGADSYK DAVRKAMFAR FTEME

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: RBM5

Associated with

Other Information

An evolutionary rearrangement of the Xp11.3-11.23 region in 3p21.3, a region frequently deleted in a variety of cancers. PubMed ID: 10486216

Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells. PubMed ID: 10497265

LUCA-15-encoded sequence variants regulate CD95-mediated apoptosis. PubMed ID: 10949932

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Antigens recognized by autologous antibody in patients with renal-cell carcinoma. PubMed ID: 10508479

Candidate tumour suppressor LUCA-15 can regulate multiple apoptotic pathways. PubMed ID: 12207175

Simultaneous acceleration of the cell cycle and suppression of apoptosis by splice variant delta-6 of the candidate tumour suppressor LUCA-15/RBM5. PubMed ID: 12581154

LUCA-15/RBM5, a putative tumour suppressor, enhances multiple receptor-initiated death signals. PubMed ID: 15192330

3p21.3 tumor suppressor gene H37/Luca15/RBM5 inhibits growth of human lung cancer cells through cell cycle arrest and apoptosis. PubMed ID: 16585163

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. PubMed ID: 17081983

Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. PubMed ID: 17332742

Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. PubMed ID: 18220336

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. PubMed ID: 18691976

RBM5/Luca-15/H37 regulates Fas alternative splice site pairing after exon definition. PubMed ID: 18851835

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5. PubMed ID: 18840686

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569