Details for: DHRS2

Gene ID: 10202

Symbol: DHRS2

Ensembl ID: ENSG00000100867

Description: dehydrogenase/reductase 2

Associated with

Other Information

Genular Protein ID: 1826765637

Symbol: DHRS2_HUMAN

Name: Protein D

UniProtKB Accession Codes:

Q13268 D3DS54 Q53GS4 Q7Z789 Q9H2R2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChEBI 5 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 15 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 MANE-Select 1 MIM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 4 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7556196

Title: A nuclear protein, synthesized in growth-arrested human hepatoblastoma cells, is a novel member of the short-chain alcohol dehydrogenase family.

PubMed ID: 7556196

DOI: 10.1111/j.1432-1033.1995.473zz.x

PubMed ID: 11997086

Title: A human short-chain dehydrogenase/reductase gene: structure, chromosomal localization, tissue expression and subcellular localization of its product.

PubMed ID: 11997086

DOI: 10.1016/s0167-4781(01)00323-2

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1847869

Title: Identification of a novel nuclear protein synthesized in growth-arrested human hepatoblastoma HepG2 cells.

PubMed ID: 1847869

DOI: 10.1111/j.1432-1033.1991.tb15759.x

PubMed ID: 11944995

Title: Genomic organization of the human gene HEP27: alternative promoter usage in HepG2 cells and monocyte-derived dendritic cells.

PubMed ID: 11944995

DOI: 10.1006/geno.2002.6743

PubMed ID: 16685466

Title: Hep27, a member of the short-chain dehydrogenase/reductase family, is an NADPH-dependent dicarbonyl reductase expressed in vascular endothelial tissue.

PubMed ID: 16685466

DOI: 10.1007/s00018-006-6013-y

PubMed ID: 19027726

Title: The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.

PubMed ID: 19027726

DOI: 10.1016/j.cbi.2008.10.040

PubMed ID: 20547751

Title: Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53.

PubMed ID: 20547751

DOI: 10.1128/mcb.01284-09

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 29106393

Title: DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma.

PubMed ID: 29106393

DOI: 10.1038/onc.2017.383

Sequence Information:

  • Length: 280
  • Mass: 29927
  • Checksum: FE76ED9CB28AB95C
  • Sequence:
    • MLSAVARGYQ GWFHPCARLS VRMSSTGIDR KGVLANRVAV VTGSTSGIGF AIARRLARDG 
AHVVISSRKQ QNVDRAMAKL QGEGLSVAGI VCHVGKAEDR EQLVAKALEH CGGVDFLVCS 
AGVNPLVGST LGTSEQIWDK ILSVNVKSPA LLLSQLLPYM ENRRGAVILV SSIAAYNPVV 
ALGVYNVSKT ALLGLTRTLA LELAPKDIRV NCVVPGIIKT DFSKVFHGNE SLWKNFKEHH 
QLQRIGESED CAGIVSFLCS PDASYVNGEN IAVAGYSTRL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.