DDX39A | ENSG00000123136 | NCBI 10212

Details for: DDX39A

Gene ID: 10212

Symbol: DDX39A

Ensembl ID: ENSG00000123136

Description: DExD-box helicase 39A

Associated with

Gene expression (transcription)
(R-HSA-74160)
Metabolism of rna
(R-HSA-8953854)
Mrna 3'-end processing
(R-HSA-72187)
Processing of capped intron-containing pre-mrna
(R-HSA-72203)
Rna polymerase ii transcription
(R-HSA-73857)
Rna polymerase ii transcription termination
(R-HSA-73856)
Transport of mature mrna derived from an intron-containing transcript
(R-HSA-159236)
Transport of mature transcript to cytoplasm
(R-HSA-72202)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Cytoplasm
(GO:0005737)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Mrna binding
(GO:0003729)
Mrna export from nucleus
(GO:0006406)
Mrna splicing, via spliceosome
(GO:0000398)
Nuclear speck
(GO:0016607)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Rna binding
(GO:0003723)
Rna export from nucleus
(GO:0006405)
Rna helicase activity
(GO:0003724)

Other Information

Proteins

ATP-dependent RNA helicase DDX39A

Genular Protein ID: 1550844412

Symbol: DX39A_HUMAN

Name: ATP-dependent RNA helicase DDX39A

UniProtKB Accession Codes:

O00148 B1Q2N1 Q8N5M0 Q9BVP6 Q9H5W0

Database IDs:

Citations:

PubMed ID: 17548965

Title: DDX39, upregulated in lung squamous cell cancer, displays RNA helicase activities and promotes cancer cell growth.

PubMed ID: 17548965

DOI: 10.4161/cbt.6.6.4192

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14667819

Title: Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.

PubMed ID: 14667819

DOI: 10.1016/s0888-7543(03)00235-0

PubMed ID: 15047853

Title: Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56.

PubMed ID: 15047853

DOI: 10.1093/nar/gkh347

PubMed ID: 16478985

Title: The UL69 transactivator protein of human cytomegalovirus interacts with DEXD/H-Box RNA helicase UAP56 to promote cytoplasmic accumulation of unspliced RNA.

PubMed ID: 16478985

DOI: 10.1128/mcb.26.5.1631-1643.2006

PubMed ID: 17196963

Title: Intracellular characterization of DDX39, a novel growth-associated RNA helicase.

PubMed ID: 17196963

DOI: 10.1016/j.yexcr.2006.11.014

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21859714

Title: Interferon-induced antiviral protein MxA interacts with the cellular RNA helicases UAP56 and URH49.

PubMed ID: 21859714

DOI: 10.1074/jbc.m111.251843

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23652018

Title: GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy.

PubMed ID: 23652018

DOI: 10.1038/ncomms2823

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

Length: 427
Mass: 49130
Checksum: 38D02D4234995574
Sequence:

MAEQDVENDL LDYDEEEEPQ APQESTPAPP KKDIKGSYVS IHSSGFRDFL LKPELLRAIV 
DCGFEHPSEV QHECIPQAIL GMDVLCQAKS GMGKTAVFVL ATLQQIEPVN GQVTVLVMCH 
TRELAFQISK EYERFSKYMP SVKVSVFFGG LSIKKDEEVL KKNCPHVVVG TPGRILALVR 
NRSFSLKNVK HFVLDECDKM LEQLDMRRDV QEIFRLTPHE KQCMMFSATL SKDIRPVCRK 
FMQDPMEVFV DDETKLTLHG LQQYYVKLKD SEKNRKLFDL LDVLEFNQVI IFVKSVQRCM 
ALAQLLVEQN FPAIAIHRGM AQEERLSRYQ QFKDFQRRIL VATNLFGRGM DIERVNIVFN 
YDMPEDSDTY LHRVARAGRF GTKGLAITFV SDENDAKILN DVQDRFEVNV AELPEEIDIS 
TYIEQSR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: DDX39A

Associated with

Other Information

DDX39, upregulated in lung squamous cell cancer, displays RNA helicase activities and promotes cancer cell growth. PubMed ID: 17548965

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. PubMed ID: 14667819

Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56. PubMed ID: 15047853

The UL69 transactivator protein of human cytomegalovirus interacts with DEXD/H-Box RNA helicase UAP56 to promote cytoplasmic accumulation of unspliced RNA. PubMed ID: 16478985

Intracellular characterization of DDX39, a novel growth-associated RNA helicase. PubMed ID: 17196963

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

Interferon-induced antiviral protein MxA interacts with the cellular RNA helicases UAP56 and URH49. PubMed ID: 21859714

Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features. PubMed ID: 22223895

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy. PubMed ID: 23652018

Uncovering global SUMOylation signaling networks in a site-specific manner. PubMed ID: 25218447

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733