OLIG2 | ENSG00000205927 | NCBI 10215

Details for: OLIG2

Gene ID: 10215

Symbol: OLIG2

Ensembl ID: ENSG00000205927

Description: oligodendrocyte transcription factor 2

Associated with

Axon development
(GO:0061564)
Chromatin
(GO:0000785)
Cytoplasm
(GO:0005737)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
E-box binding
(GO:0070888)
Hmg box domain binding
(GO:0071837)
Identical protein binding
(GO:0042802)
Myelination
(GO:0042552)
Negative regulation of neuron differentiation
(GO:0045665)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neuron fate commitment
(GO:0048663)
Nucleus
(GO:0005634)
Positive regulation of oligodendrocyte differentiation
(GO:0048714)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Sensory organ development
(GO:0007423)
Sequence-specific double-stranded dna binding
(GO:1990837)
Spinal cord motor neuron differentiation
(GO:0021522)
Spinal cord oligodendrocyte cell fate specification
(GO:0021530)
Thalamus development
(GO:0021794)

Other Information

Proteins

Oligodendrocyte transcription factor 2

Genular Protein ID: 2498933842

Symbol: OLIG2_HUMAN

Name: Oligodendrocyte transcription factor 2

UniProtKB Accession Codes:

Q13516 B3KRF3 Q05BP9 Q49AL3 Q86X04 Q9NZ14

Database IDs:

Citations:

PubMed ID: 10737801

Title: The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene.

PubMed ID: 10737801

DOI: 10.1073/pnas.97.7.3497

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11498220

Title: OLIG2 as a specific marker of oligodendroglial tumour cells.

PubMed ID: 11498220

DOI: 10.1016/s0140-6736(01)05499-x

PubMed ID: 11526205

Title: Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors.

PubMed ID: 11526205

DOI: 10.1073/pnas.181340798

Sequence Information:

Length: 323
Mass: 32385
Checksum: 0EC9223961062509
Sequence:

MDSDASLVSS RPSSPEPDDL FLPARSKGSS GSAFTGGTVS SSTPSDCPPE LSAELRGAMG 
SAGAHPGDKL GGSGFKSSSS STSSSTSSAA ASSTKKDKKQ MTEPELQQLR LKINSRERKR 
MHDLNIAMDG LREVMPYAHG PSVRKLSKIA TLLLARNYIL MLTNSLEEMK RLVSEIYGGH 
HAGFHPSACG GLAHSAPLPA ATAHPAAAAH AAHHPAVHHP ILPPAAAAAA AAAAAAAVSS 
ASLPGSGLPS VGSIRPPHGL LKSPSAAAAA PLGGGGGGSG ASGGFQHWGG MPCPCSMCQV 
PPPHHHVSAM GAGSLPRLTS DAK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: OLIG2

Associated with

Other Information

The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene. PubMed ID: 10737801

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334