Details for: KLRG1

Gene ID: 10219

Symbol: KLRG1

Ensembl ID: ENSG00000139187

Description: killer cell lectin like receptor G1

Associated with

Other Information

Genular Protein ID: 2255923319

Symbol: KLRG1_HUMAN

Name: Killer cell lectin-like receptor subfamily G member 1

UniProtKB Accession Codes:

Q96E93 B7ZAM2 O43198 O75613

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 9 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 9765598

Title: Human MAFA has alternatively spliced variants.

PubMed ID: 9765598

DOI: 10.1016/s0167-4781(98)00107-9

PubMed ID: 9842918

Title: MAFA-L, an ITIM-containing receptor encoded by the human NK cell gene complex and expressed by basophils and NK cells.

PubMed ID: 9842918

DOI: 10.1002/(sici)1521-4141(199811)28:11<3755::aid-immu3755>3.0.co;2-3

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15879103

Title: Expression of killer cell lectin-like receptor G1 on antigen-specific human CD8+ T lymphocytes during active, latent, and resolved infection and its relation with CD57.

PubMed ID: 15879103

DOI: 10.4049/jimmunol.174.10.6088

PubMed ID: 17617594

Title: Tumor-associated E-cadherin mutations affect binding to the killer cell lectin-like receptor G1 in humans.

PubMed ID: 17617594

DOI: 10.4049/jimmunol.179.2.1022

PubMed ID: 19604491

Title: Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition.

PubMed ID: 19604491

DOI: 10.1016/j.immuni.2009.04.019

Sequence Information:

  • Length: 195
  • Mass: 21831
  • Checksum: 178EE98E08EEC473
  • Sequence:
    • MTDSVIYSML ELPTATQAQN DYGPQQKSSS SRPSCSCLVA IALGLLTAVL LSVLLYQWIL 
CQGSNYSTCA SCPSCPDRWM KYGNHCYYFS VEEKDWNSSL EFCLARDSHL LVITDNQEMS 
LLQVFLSEAF CWIGLRNNSG WRWEDGSPLN FSRISSNSFV QTCGAINKNG LQASSCEVPL 
HWVCKKCPFA DQALF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.