Details for: GDF11

Gene ID: 10220

Symbol: GDF11

Ensembl ID: ENSG00000135414

Description: growth differentiation factor 11

Associated with

Other Information

Genular Protein ID: 3732662789

Symbol: GDF11_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10075854

Title: A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos.

PubMed ID: 10075854

DOI: 10.1006/dbio.1998.9191

PubMed ID: 10391213

Title: Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11.

PubMed ID: 10391213

DOI: 10.1038/10320

PubMed ID: 31215115

Title: Mutations in GDF11 and the extracellular antagonist, Follistatin, as a likely cause of Mendelian forms of orofacial clefting in humans.

PubMed ID: 31215115

DOI: 10.1002/humu.23793

PubMed ID: 26919518

Title: Crystal structure of human GDF11.

PubMed ID: 26919518

DOI: 10.1107/s2053230x16001588

PubMed ID: 28257634

Title: Structural basis for potency differences between GDF8 and GDF11.

PubMed ID: 28257634

DOI: 10.1186/s12915-017-0350-1

Sequence Information:

  • Length: 407
  • Mass: 45091
  • Checksum: E8FF48E363635BA8
  • Sequence:
  • MVLAAPLLLG FLLLALELRP RGEAAEGPAA AAAAAAAAAA AGVGGERSSR PAPSVAPEPD 
    GCPVCVWRQH SRELRLESIK SQILSKLRLK EAPNISREVV KQLLPKAPPL QQILDLHDFQ 
    GDALQPEDFL EEDEYHATTE TVISMAQETD PAVQTDGSPL CCHFHFSPKV MFTKVLKAQL 
    WVYLRPVPRP ATVYLQILRL KPLTGEGTAG GGGGGRRHIR IRSLKIELHS RSGHWQSIDF 
    KQVLHSWFRQ PQSNWGIEIN AFDPSGTDLA VTSLGPGAEG LHPFMELRVL ENTKRSRRNL 
    GLDCDEHSSE SRCCRYPLTV DFEAFGWDWI IAPKRYKANY CSGQCEYMFM QKYPHTHLVQ 
    QANPRGSAGP CCTPTKMSPI NMLYFNDKQQ IIYGKIPGMV VDRCGCS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.