Details for: POP7

Gene ID: 10248

Symbol: POP7

Ensembl ID: ENSG00000172336

Description: POP7 homolog, ribonuclease P/MRP subunit

Associated with

Other Information

Genular Protein ID: 2564845594

Symbol: POP7_HUMAN

Name: Ribonuclease P protein subunit p20

UniProtKB Accession Codes:

O75817 A4D2E0 Q9BV74

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ComplexPortal 2 DNASU 1 DisGeNET 1 DisProt 1 EMBL 4 EMDB 2 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 14 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 4 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9630247

Title: Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P.

PubMed ID: 9630247

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15096576

Title: Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex.

PubMed ID: 15096576

DOI: 10.1093/nar/gkh539

PubMed ID: 14715275

Title: Rpp20 interacts with SMN and is re-distributed into SMN granules in response to stress.

PubMed ID: 14715275

DOI: 10.1016/j.bbrc.2003.12.084

PubMed ID: 16723659

Title: Differential association of protein subunits with the human RNase MRP and RNase P complexes.

PubMed ID: 16723659

DOI: 10.1261/rna.2293906

PubMed ID: 20215441

Title: Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA.

PubMed ID: 20215441

DOI: 10.1093/nar/gkq141

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 28115465

Title: Targeted CRISPR disruption reveals a role for RNase MRP RNA in human preribosomal RNA processing.

PubMed ID: 28115465

DOI: 10.1101/gad.286963.116

PubMed ID: 30454648

Title: Cryo-EM Structure of the Human Ribonuclease P Holoenzyme.

PubMed ID: 30454648

DOI: 10.1016/j.cell.2018.10.003

PubMed ID: 29625199

Title: Crystal Structure of Human Rpp20/Rpp25 Reveals Quaternary Level Adaptation of the Alba Scaffold as Structural Basis for Single-stranded RNA Binding.

PubMed ID: 29625199

DOI: 10.1016/j.jmb.2018.03.029

Sequence Information:

  • Length: 140
  • Mass: 15651
  • Checksum: CA380F7D273A64B3
  • Sequence:
    • MAENREPRGA VEAELDPVEY TLRKRLPSRL PRRPNDIYVN MKTDFKAQLA RCQKLLDGGA 
RGQNACSEIY IHGLGLAINR AINIALQLQA GSFGSLQVAA NTSTVELVDE LEPETDTREP 
LTRIRNNSAI HIRVFRVTPK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.