Details for: SRRM1

Gene ID: 10250

Symbol: SRRM1

Ensembl ID: ENSG00000133226

Description: serine and arginine repetitive matrix 1

Associated with

Other Information

Genular Protein ID: 809222640

Symbol: SRRM1_HUMAN

Name: Serine/arginine repetitive matrix protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9531537

Title: A coactivator of pre-mRNA splicing.

PubMed ID: 9531537

DOI: 10.1101/gad.12.7.996

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10339552

Title: The SRm160/300 splicing coactivator is required for exon-enhancer function.

PubMed ID: 10339552

DOI: 10.1073/pnas.96.11.6125

PubMed ID: 11118221

Title: The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions.

PubMed ID: 11118221

DOI: 10.1093/emboj/19.24.6860

PubMed ID: 10809668

Title: Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions.

PubMed ID: 10809668

PubMed ID: 10668804

Title: The SRm160/300 splicing coactivator subunits.

PubMed ID: 10668804

DOI: 10.1017/s1355838200991982

PubMed ID: 11546874

Title: Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1.

PubMed ID: 11546874

DOI: 10.1126/science.1062786

PubMed ID: 12093754

Title: The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling.

PubMed ID: 12093754

DOI: 10.1093/emboj/cdf345

PubMed ID: 11739730

Title: SRm160 splicing coactivator promotes transcript 3'-end cleavage.

PubMed ID: 11739730

DOI: 10.1128/mcb.22.1.148-160.2002

PubMed ID: 11991638

Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

PubMed ID: 11991638

DOI: 10.1017/s1355838202021088

PubMed ID: 12944400

Title: An evolutionarily conserved role for SRm160 in 3'-end processing that functions independently of exon junction complex formation.

PubMed ID: 12944400

DOI: 10.1074/jbc.m306856200

PubMed ID: 12624182

Title: The spatial targeting and nuclear matrix binding domains of SRm160.

PubMed ID: 12624182

DOI: 10.1073/pnas.0438055100

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 15024032

Title: In vitro FRAP reveals the ATP-dependent nuclear mobilization of the exon junction complex protein SRm160.

PubMed ID: 15024032

DOI: 10.1083/jcb.200307002

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17924679

Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.

PubMed ID: 17924679

DOI: 10.1021/pr070152u

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 29973724

Title: Kinase-controlled phase transition of membraneless organelles in mitosis.

PubMed ID: 29973724

DOI: 10.1038/s41586-018-0279-8

PubMed ID: 12600940

Title: Structure and function of the PWI motif: a novel nucleic acid-binding domain that facilitates pre-mRNA processing.

PubMed ID: 12600940

DOI: 10.1101/gad.1060403

PubMed ID: 33509932

Title: Structure of the activated human minor spliceosome.

PubMed ID: 33509932

DOI: 10.1126/science.abg0879

Sequence Information:

  • Length: 904
  • Mass: 102335
  • Checksum: 27D4D2A48EDBFED3
  • Sequence:
  • MDAGFFRGTS AEQDNRFSNK QKKLLKQLKF AECLEKKVDM SKVNLEVIKP WITKRVTEIL 
    GFEDDVVIEF IFNQLEVKNP DSKMMQINLT GFLNGKNARE FMGELWPLLL SAQENIAGIP 
    SAFLELKKEE IKQRQIEQEK LASMKKQDED KDKRDKEEKE SSREKRERSR SPRRRKSRSP 
    SPRRRSSPVR RERKRSHSRS PRHRTKSRSP SPAPEKKEKT PELPEPSVKV KEPSVQEATS 
    TSDILKVPKP EPIPEPKEPS PEKNSKKEKE KEKTRPRSRS RSKSRSRTRS RSPSHTRPRR 
    RHRSRSRSYS PRRRPSPRRR PSPRRRTPPR RMPPPPRHRR SRSPVRRRRR SSASLSGSSS 
    SSSSSRSRSP PKKPPKRTSS PPRKTRRLSP SASPPRRRHR PSPPATPPPK TRHSPTPQQS 
    NRTRKSRVSV SPGRTSGKVT KHKGTEKRES PSPAPKPRKV ELSESEEDKG GKMAAADSVQ 
    QRRQYRRQNQ QSSSDSGSSS SSEDERPKRS HVKNGEVGRR RRHSPSRSAS PSPRKRQKET 
    SPRGRRRRSP SPPPTRRRRS PSPAPPPRRR RTPTPPPRRR TPSPPPRRRS PSPRRYSPPI 
    QRRYSPSPPP KRRTASPPPP PKRRASPSPP PKRRVSHSPP PKQRSSPVTK RRSPSLSSKH 
    RKGSSPSRST REARSPQPNK RHSPSPRPRA PQTSSSPPPV RRGASSSPQR RQSPSPSTRP 
    IRRVSRTPEP KKIKKAASPS PQSVRRVSSS RSVSGSPEPA AKKPPAPPSP VQSQSPSTNW 
    SPAVPVKKAK SPTPSPSPPR NSDQEGGGKK KKKKKDKKHK KDKKHKKHKK HKKEKAVAAA 
    AAAAVTPAAI AAATTTLAQE EPVAAPEPKK ETESEAEDNL DDLEKHLREK ALRSMRKAQV 
    SPQS

Genular Protein ID: 1232902720

Symbol: B7Z7U0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 916
  • Mass: 103797
  • Checksum: D6E2CA5A76B4B4E3
  • Sequence:
  • MDAGFFRGTS AEQDNRFSNK QKKLLKQLKF AECLEKKVDM SKVNLEVIKP WITKRVTEIL 
    GFEDDVVIEF IFNQLEVKNP DSKMMQINLT GFLNGKNARE FMGELWPLLL SAQENIAGIP 
    SAFLELKKEE IKQRQIEQEK LASMKKQDED KDKRDKEEKE SSREKRERSR SPRRRKSRSP 
    SPRRRSSPVR RERKRSHSRS PRHRTKSRSP SPAPEKKEKT PELPEPSVKV KEPSVQEATS 
    TSDILKVPKP EPIPEPKEPS PEKNSKKEKE KEKTRPRSRS RSKSRSRTRS RSPSHTRPRR 
    RHRSRSRSYS PRRRPSPRRR PSPRRRTPPR RMPPPPRHRR SRSPVRRRRR SSASLSGSSS 
    SSSSSRSRSP PKKPPKRTSS PPRKTRRLSP SASPPRRRHR PSPPATPPPK TRHSPTPQQS 
    NRTRKSRVSV SPGRTSVTKH KGTEKRESPS PAPKPRKVEL SESEEDKGGK MAAADSVQQR 
    RQYRRQDQQS SSDSGSSSSS EDERPKRSHV KNGEVGRRRR HSPSRSASPS PRKRQKETSP 
    RMQMGKRWQS PVTKSGRRRR SPSPPPTRRR RSPSPAPPPR RRRTPTPPPR RRTPSPPPRR 
    RSPSPRRYSP PIQRRYSPSP PPKRRTASPP PPPKRRASPS PPPKRRVSHS PPPKQRSSPV 
    TKRRSPSLSS KHRKGSSPSR STREARSPQP NKRHSPSPRP RAPQTSSSPP PVRRGASSSP 
    QRRQSPSPST RPIRRVSRTP EPKKIKKAAS PSPQSVRRVS SSRSVSGSPE PAAKKPPAPP 
    SPVQSQSPST NWSPAVPVKK AKSPTPSPSP PRNSDQEGGG KKKKKKKDKK HKKDKKHKKH 
    KKHKKEKAVA AAAAAAVTPA AIAAATTTLA QEEPVAAPEP KKETESEAED NLDDLEKHLR 
    EKALRSMRKA QVSPQS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.