Details for: SPRY3

Gene ID: 10251

Symbol: SPRY3

Ensembl ID: ENSG00000168939

Description: sprouty RTK signaling antagonist 3

Associated with

Other Information

Genular Protein ID: 3023606928

Symbol: SPY3_HUMAN

Name: N/A

UniProtKB Accession Codes:

O43610 A8K0H8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 3 GO 9 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 2 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10655549

Title: Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.

PubMed ID: 10655549

DOI: 10.1093/hmg/9.3.395

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9458049

Title: Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways.

PubMed ID: 9458049

DOI: 10.1016/s0092-8674(00)80919-8

PubMed ID: 17974561

Title: Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.

PubMed ID: 17974561

DOI: 10.1074/jbc.m705457200

PubMed ID: 26089202

Title: Regulation of SPRY3 by X chromosome and PAR2-linked promoters in an autism susceptibility region.

PubMed ID: 26089202

DOI: 10.1093/hmg/ddv231

PubMed ID: 29293652

Title: USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.

PubMed ID: 29293652

DOI: 10.1371/journal.pone.0190513

PubMed ID: 30878395

Title: MicroRNA-143-3p promotes human cardiac fibrosis via targeting sprouty3 after myocardial infarction.

PubMed ID: 30878395

DOI: 10.1016/j.yjmcc.2019.03.005

Sequence Information:

  • Length: 288
  • Mass: 31222
  • Checksum: 62C59F5E897D99B8
  • Sequence:
    • MDAAVTDDFQ QILPIEQLRS THASNDYVER PPAPCKQALS SPSLIVQTHK SDWSLATMPT 
SLPRSLSQCH QLQPLPQHLS QSSIASSMSH STTASDQRLL ASITPSPSGQ SIIRTQPGAG 
VHPKADGALK GEAEQSAGHP SEHLFICEEC GRCKCVPCTA ARPLPSCWLC NQRCLCSAES 
LLDYGTCLCC VKGLFYHCST DDEDNCADEP CSCGPSSCFV RWAAMSLISL FLPCLCCYLP 
TRGCLHLCQQ GYDSLRRPGC RCKRHTNTVC RKISSGSAPF PKAQEKSV

Genular Protein ID: 1284634698

Symbol: Q6ZUP3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6ZUP3

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GenomeRNAi 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 RefSeq 2

Sequence Information:

  • Length: 125
  • Mass: 13335
  • Checksum: C9C25D301AFCA7C1
  • Sequence:
    • MDAAVTDDFQ QILPIEQLRS THASNDYVER PPAPCKQALS SPSLIVQTHK SDWSLATMPT 
SLPRSLSQCH QLQPLPQHLS QSSIASSMSH STTASSTTAP LMMKTTVLMS PALVGLVLAL 
SAGQP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.