SPRY1 | ENSG00000164056 | NCBI 10252

Details for: SPRY1

Gene ID: 10252

Symbol: SPRY1

Ensembl ID: ENSG00000164056

Description: sprouty RTK signaling antagonist 1

Associated with

Egfr downregulation
(R-HSA-182971)
Signaling by egfr
(R-HSA-177929)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signal transduction
(R-HSA-162582)
Animal organ development
(GO:0048513)
Bud elongation involved in lung branching
(GO:0060449)
Cytosol
(GO:0005829)
Epithelial to mesenchymal transition involved in cardiac fibroblast development
(GO:0060940)
Erk1 and erk2 cascade
(GO:0070371)
Establishment of mitotic spindle orientation
(GO:0000132)
Golgi apparatus
(GO:0005794)
Metanephros development
(GO:0001656)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of epithelial to mesenchymal transition
(GO:0010719)
Negative regulation of erk1 and erk2 cascade
(GO:0070373)
Negative regulation of fibroblast growth factor receptor signaling pathway
(GO:0040037)
Negative regulation of lens fiber cell differentiation
(GO:1902747)
Negative regulation of map kinase activity
(GO:0043407)
Negative regulation of neurotrophin trk receptor signaling pathway
(GO:0051387)
Negative regulation of ras protein signal transduction
(GO:0046580)
Negative regulation of transforming growth factor beta receptor signaling pathway
(GO:0030512)
Nucleoplasm
(GO:0005654)
Organ induction
(GO:0001759)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Ureteric bud development
(GO:0001657)

Other Information

Proteins

Protein sprouty homolog 1

Genular Protein ID: 882914870

Symbol: SPY1_HUMAN

Name: Protein sprouty homolog 1

UniProtKB Accession Codes:

O43609 D3DNX6 Q6PNE0

Database IDs:

Citations:

PubMed ID: 14533010

Title: Identification and expression analysis of a novel splice variant of human Sprouty1 gene.

PubMed ID: 14533010

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9458049

Title: Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways.

PubMed ID: 9458049

DOI: 10.1016/s0092-8674(00)80919-8

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

Sequence Information:

Length: 319
Mass: 35122
Checksum: 40E2D4D12816E057
Sequence:

MDPQNQHGSG SSLVVIQQPS LDSRQRLDYE REIQPTAILS LDQIKAIRGS NEYTEGPSVV 
KRPAPRTAPR QEKHERTHEI IPINVNNNYE HRHTSHLGHA VLPSNARGPI LSRSTSTGSA 
ASSGSNSSAS SEQGLLGRSP PTRPVPGHRS ERAIRTQPKQ LIVDDLKGSL KEDLTQHKFI 
CEQCGKCKCG ECTAPRTLPS CLACNRQCLC SAESMVEYGT CMCLVKGIFY HCSNDDEGDS 
YSDNPCSCSQ SHCCSRYLCM GAMSLFLPCL LCYPPAKGCL KLCRRCYDWI HRPGCRCKNS 
NTVYCKLESC PSRGQGKPS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SPRY1

Associated with

Other Information

Identification and expression analysis of a novel splice variant of human Sprouty1 gene. PubMed ID: 14533010

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. PubMed ID: 9458049

Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features. PubMed ID: 22223895

Database document:

PubMed ID: 14533010

PubMed ID: 15489334

PubMed ID: 9458049

PubMed ID: 22223895