Details for: ABCC4

Gene ID: 10257

Symbol: ABCC4

Ensembl ID: ENSG00000125257

Description: ATP binding cassette subfamily C member 4 (PEL blood group)

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 3.19
    Marker Score: 1,683
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 2.95
    Marker Score: 1,468
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 2.65
    Marker Score: 11,038
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 2.33
    Marker Score: 843
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 2.27
    Marker Score: 19,183
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 2.24
    Marker Score: 1,988
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.22
    Marker Score: 4,870
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 2.21
    Marker Score: 1,534
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.86
    Marker Score: 3,572
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.75
    Marker Score: 7,309
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.63
    Marker Score: 3,308
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.6
    Marker Score: 3,771
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.57
    Marker Score: 2,275
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.49
    Marker Score: 3,737
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.48
    Marker Score: 884
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 1.47
    Marker Score: 2,442
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168,462
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.39
    Marker Score: 14,314
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 1.36
    Marker Score: 1,303
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.36
    Marker Score: 21,818
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.29
    Marker Score: 415
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.27
    Marker Score: 4,518
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.25
    Marker Score: 616
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.18
    Marker Score: 11,143
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.15
    Marker Score: 18,007
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 1.14
    Marker Score: 231
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.14
    Marker Score: 1,228
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.11
    Marker Score: 667
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.08
    Marker Score: 1,100
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.07
    Marker Score: 623
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.03
    Marker Score: 1,088
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 1.03
    Marker Score: 331
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.03
    Marker Score: 296
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.01
    Marker Score: 1,490
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.01
    Marker Score: 316
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 1.01
    Marker Score: 319
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,768
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,993
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.99
    Marker Score: 5,977
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,402
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.98
    Marker Score: 1,782
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.95
    Marker Score: 492
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,408
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.95
    Marker Score: 447
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.94
    Marker Score: 343
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.92
    Marker Score: 313
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.92
    Marker Score: 19,556
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.91
    Marker Score: 7,853
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,723
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.9
    Marker Score: 361
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.9
    Marker Score: 1,016
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.88
    Marker Score: 761
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.88
    Marker Score: 762
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.88
    Marker Score: 5,006
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,294
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.87
    Marker Score: 314
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.86
    Marker Score: 271
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.85
    Marker Score: 1,554
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.83
    Marker Score: 3,395
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.82
    Marker Score: 209
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 0.82
    Marker Score: 5,319
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.81
    Marker Score: 550
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.8
    Marker Score: 1,303
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.8
    Marker Score: 608
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.79
    Marker Score: 955
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.79
    Marker Score: 230
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 0.77
    Marker Score: 201
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 0.77
    Marker Score: 665
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 0.77
    Marker Score: 204
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.76
    Marker Score: 5,623
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 0.75
    Marker Score: 305
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.74
    Marker Score: 383
  • Cell Name: club cell (CL0000158)
    Fold Change: 0.74
    Marker Score: 860
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.73
    Marker Score: 271
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.72
    Marker Score: 1,110
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.72
    Marker Score: 3,004
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 0.71
    Marker Score: 1,137
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.7
    Marker Score: 639
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.7
    Marker Score: 172
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.69
    Marker Score: 743
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 173
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.67
    Marker Score: 450
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.66
    Marker Score: 314
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.65
    Marker Score: 24,576
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.64
    Marker Score: 1,079
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.64
    Marker Score: 324
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.64
    Marker Score: 804
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.64
    Marker Score: 627
  • Cell Name: renal intercalated cell (CL0005010)
    Fold Change: 0.63
    Marker Score: 336
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.62
    Marker Score: 871
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.61
    Marker Score: 255
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.61
    Marker Score: 157
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.6
    Marker Score: 145
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 0.59
    Marker Score: 3,113
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: 0.58
    Marker Score: 240
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 0.57
    Marker Score: 129
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.57
    Marker Score: 35,251
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.57
    Marker Score: 231
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 0.57
    Marker Score: 541
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.56
    Marker Score: 163

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ABCC4 is a transmembrane protein belonging to the ABC family of transporters, which are characterized by their ability to use ATP hydrolysis to drive the transport of molecules across cellular membranes. ABCC4 is a substrate for the enzyme prostaglandin dehydrogenase (NAD+), which suggests that it may play a role in the metabolism of prostaglandins. The protein is also capable of transporting a wide range of molecules, including xenobiotics, glutathione conjugates, and urates, which are involved in various cellular processes such as detoxification, immune response, and inflammation. **Pathways and Functions:** ABCC4 is involved in various cellular processes, including: 1. **Detoxification:** ABCC4 is capable of transporting xenobiotics and glutathione conjugates across cellular membranes, which may help to detoxify these substances and prevent their accumulation in the body. 2. **Immune Response:** ABCC4 is expressed in immune cells, such as macrophages and microglial cells, where it may contribute to immune regulation and response. 3. **Inflammation:** ABCC4 is involved in the transport of prostaglandins and leukotrienes, which are involved in the regulation of inflammation. 4. **Cellular Transport:** ABCC4 is capable of transporting a wide range of molecules, including urates, across cellular membranes, which may help to regulate cellular metabolism and function. **Clinical Significance:** ABCC4 has been implicated in various diseases, including: 1. **Cancer:** Overexpression of ABCC4 has been observed in certain types of cancer, such as breast and lung cancer, where it may contribute to chemotherapy resistance. 2. **Neurological Disorders:** ABCC4 has been implicated in various neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it may contribute to the accumulation of toxic substances in the brain. 3. **Infectious Diseases:** ABCC4 has been implicated in the transport of antimicrobial peptides and other immune regulators, which may help to regulate the immune response to infection. 4. **Metabolic Disorders:** ABCC4 has been implicated in the regulation of glucose and lipid metabolism, which may contribute to the development of metabolic disorders, such as type 2 diabetes and obesity. In conclusion, the ABCC4 gene is a multifaceted transporter involved in various cellular processes, including detoxification, immune response, inflammation, and cellular transport. Its clinical significance is evident in its involvement in various diseases, including cancer, neurological disorders, infectious diseases, and metabolic disorders. Further research is needed to fully understand the role of ABCC4 in human health and disease.

Genular Protein ID: 360130207

Symbol: MRP4_HUMAN

Name: ATP-binding cassette sub-family C member 4

UniProtKB Accession Codes:

O15439 A9Z1Z7 B7Z3Q7 Q8IVZ4 Q8IZN6 Q8NEW8 Q9Y6J2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 4 CTD 1 ChEBI 100 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DrugBank 50 DrugCentral 1 EC 2 EMBL 13 EMDB 12 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 37 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 10 PRO 1 PROSITE 3 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 4 RefSeq 4 Rhea 35 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9661885

Title: Isolation of MOAT-B, a widely expressed multidrug resistance-associated protein/canalicular multispecific organic anion transporter-related transporter.

PubMed ID: 9661885

PubMed ID: 12105214

Title: Expression of MRP4 confers resistance to ganciclovir and compromises bystander cell killing.

PubMed ID: 12105214

DOI: 10.1074/jbc.m203262200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9270026

Title: Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

PubMed ID: 9270026

PubMed ID: 11106685

Title: Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells.

PubMed ID: 11106685

DOI: 10.1093/jnci/92.23.1934

PubMed ID: 11856762

Title: The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.

PubMed ID: 11856762

DOI: 10.1681/asn.v133595

PubMed ID: 12883481

Title: Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.

PubMed ID: 12883481

DOI: 10.1053/jhep.2003.50331

PubMed ID: 12523936

Title: Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

PubMed ID: 12523936

DOI: 10.1042/bj20021886

PubMed ID: 12835412

Title: The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.

PubMed ID: 12835412

DOI: 10.1073/pnas.1033060100

PubMed ID: 15364914

Title: Multidrug resistance protein 4 (ABCC4)-mediated ATP hydrolysis: effect of transport substrates and characterization of the post-hydrolysis transition state.

PubMed ID: 15364914

DOI: 10.1074/jbc.m408849200

PubMed ID: 15454390

Title: Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites.

PubMed ID: 15454390

DOI: 10.1152/ajprenal.00133.2004

PubMed ID: 16282361

Title: Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione.

PubMed ID: 16282361

DOI: 10.1152/ajpgi.00354.2005

PubMed ID: 17344354

Title: Involvement of MRP4 (ABCC4) in the luminal efflux of ceftizoxime and cefazolin in the kidney.

PubMed ID: 17344354

DOI: 10.1124/mol.106.031823

PubMed ID: 17959747

Title: ATP-dependent transport of leukotrienes B4 and C4 by the multidrug resistance protein ABCC4 (MRP4).

PubMed ID: 17959747

DOI: 10.1124/jpet.107.131342

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22411990

Title: Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4.

PubMed ID: 22411990

DOI: 10.1074/jbc.m111.337931

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 18300232

Title: 6-mercaptopurine and 9-(2-phosphonyl-methoxyethyl) adenine (PMEA) transport altered by two missense mutations in the drug transporter gene ABCC4.

PubMed ID: 18300232

DOI: 10.1002/humu.20694

PubMed ID: 26721430

Title: N-linked glycans do not affect plasma membrane localization of multidrug resistance protein 4 (MRP4) but selectively alter its prostaglandin E2 transport activity.

PubMed ID: 26721430

DOI: 10.1016/j.bbrc.2015.12.095

PubMed ID: 20547088

Title: A Japanese-specific allele in the GALNT11 gene.

PubMed ID: 20547088

DOI: 10.1016/j.legalmed.2010.04.001

Sequence Information:

  • Length: 1325
  • Mass: 149527
  • Checksum: BF2D53136B78C0BA
  • Sequence:
    • MLPVYQEVKP NPLQDANLCS RVFFWWLNPL FKIGHKRRLE EDDMYSVLPE DRSQHLGEEL 
QGFWDKEVLR AENDAQKPSL TRAIIKCYWK SYLVLGIFTL IEESAKVIQP IFLGKIINYF 
ENYDPMDSVA LNTAYAYATV LTFCTLILAI LHHLYFYHVQ CAGMRLRVAM CHMIYRKALR 
LSNMAMGKTT TGQIVNLLSN DVNKFDQVTV FLHFLWAGPL QAIAVTALLW MEIGISCLAG 
MAVLIILLPL QSCFGKLFSS LRSKTATFTD ARIRTMNEVI TGIRIIKMYA WEKSFSNLIT 
NLRKKEISKI LRSSCLRGMN LASFFSASKI IVFVTFTTYV LLGSVITASR VFVAVTLYGA 
VRLTVTLFFP SAIERVSEAI VSIRRIQTFL LLDEISQRNR QLPSDGKKMV HVQDFTAFWD 
KASETPTLQG LSFTVRPGEL LAVVGPVGAG KSSLLSAVLG ELAPSHGLVS VHGRIAYVSQ 
QPWVFSGTLR SNILFGKKYE KERYEKVIKA CALKKDLQLL EDGDLTVIGD RGTTLSGGQK 
ARVNLARAVY QDADIYLLDD PLSAVDAEVS RHLFELCICQ ILHEKITILV THQLQYLKAA 
SQILILKDGK MVQKGTYTEF LKSGIDFGSL LKKDNEESEQ PPVPGTPTLR NRTFSESSVW 
SQQSSRPSLK DGALESQDTE NVPVTLSEEN RSEGKVGFQA YKNYFRAGAH WIVFIFLILL 
NTAAQVAYVL QDWWLSYWAN KQSMLNVTVN GGGNVTEKLD LNWYLGIYSG LTVATVLFGI 
ARSLLVFYVL VNSSQTLHNK MFESILKAPV LFFDRNPIGR ILNRFSKDIG HLDDLLPLTF 
LDFIQTLLQV VGVVSVAVAV IPWIAIPLVP LGIIFIFLRR YFLETSRDVK RLESTTRSPV 
FSHLSSSLQG LWTIRAYKAE ERCQELFDAH QDLHSEAWFL FLTTSRWFAV RLDAICAMFV 
IIVAFGSLIL AKTLDAGQVG LALSYALTLM GMFQWCVRQS AEVENMMISV ERVIEYTDLE 
KEAPWEYQKR PPPAWPHEGV IIFDNVNFMY SPGGPLVLKH LTALIKSQEK VGIVGRTGAG 
KSSLISALFR LSEPEGKIWI DKILTTEIGL HDLRKKMSII PQEPVLFTGT MRKNLDPFNE 
HTDEELWNAL QEVQLKETIE DLPGKMDTEL AESGSNFSVG QRQLVCLARA ILRKNQILII 
DEATANVDPR TDELIQKKIR EKFAHCTVLT IAHRLNTIID SDKIMVLDSG RLKEYDEPYV 
LLQNKESLFY KMVQQLGKAE AAALTETAKQ VYFKRNYPHI GHTDHMVTNT SNGQPSTLTI 
FETAL

Genular Protein ID: 2940327804

Symbol: A8K2Q2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K2Q2

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 EMBL 2 GO 4 Gene3D 2 GenomeRNAi 1 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 1 Pfam 2 RefSeq 4 SAM 2 SMART 1 SUPFAM 2

Sequence Information:

  • Length: 859
  • Mass: 96840
  • Checksum: A254809A2B0DA423
  • Sequence:
    • MLPVYQEVKP NPLQDANLCS RVFFWWLNPL FKIGHKRRLE EDDMYSVLPE DRSQHLGEEL 
QGFWDKEVLR AENDAQKPSL TRAIIKCYWK SYLVLGIFTL IEESAKVIQP IFLGKIINYF 
ENYDPMDSVA LNTAYAYATV LTFCTLILAI LHHLYFYHVQ CAGMRLRVAM CHMIYRKALR 
LSNMAMGKTT TGQIVNLLSN DVNKFDQVTV FLHFLWAGPL QAIAVTALLW MEIGISCLAG 
MAVLIILLPL QSCFGKLFSS LRSKTATFTD ARIRTMNEVI TGIRIIKMYA WEKSFSNLIT 
NLRKKEISKI LRSSCLRGMN LASFFSASKI IVFVTFTTYV LLGSVITASR VFVAVTLYGA 
VRLTVTLFFP SAIERVSEAI VSIRRIQTFL LLDEISQRNR QLPSDGKKMV HVQDFTAFWD 
KASETPTLQG LSFTVRPGEL LAVVGPVGAG KSSLLSAVLG ELAPSHGLVS VHGRIAYVSQ 
QPWVFSGTLR SNILFGKKYE KERYEKVIKA CALKKDLQLL EDGDLTVIGD RGTTLSGGQK 
ARVNLARAVY QDADIYLLDD PLSAVDAEVS RHLFELCICQ ILHEKITILV THQLQYLKAA 
SQILILKDGK MVQKGTYTEF LKSGIDFGSL LKKDNEESEQ PPVPGTPTLR NRTFSESSVW 
SQQSSRPSLK DGALESQDTE NVPVTLSEEN RSEGKVGFQA YKNYFRAGAH WIVFIFLILL 
NTAAQVAYVL QDWWLSYWAN KQSMLNVTVN GGGNVTEKLD LNWYLGIYSG LTVATVLFGI 
ARSLLVFYVL VNSSQTLHNK MFESILKAPV LFFDRNPIGR ILIRFSKDIG HLDDLLPLTF 
LDFIQRWDLA VLSWLVSNS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.