Details for: DENND4A

Gene ID: 10260

Symbol: DENND4A

Ensembl ID: ENSG00000174485

Description: DENN domain containing 4A

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 3.41
    Marker Score: 4,585
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 3.3
    Marker Score: 3,998
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.28
    Marker Score: 13,733
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.84
    Marker Score: 831
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.61
    Marker Score: 55,710
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 2.57
    Marker Score: 1,691
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.48
    Marker Score: 5,451
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.47
    Marker Score: 18,904
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.45
    Marker Score: 48,697
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.44
    Marker Score: 2,806
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.42
    Marker Score: 92,027
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 2.32
    Marker Score: 3,366
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 2.3
    Marker Score: 1,143
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.29
    Marker Score: 1,335
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 2.27
    Marker Score: 822
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.26
    Marker Score: 5,655
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.26
    Marker Score: 33,746
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.25
    Marker Score: 9,336
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.2
    Marker Score: 695
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.18
    Marker Score: 10,074
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 2.13
    Marker Score: 5,108
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.13
    Marker Score: 1,247
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.13
    Marker Score: 78,567
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.09
    Marker Score: 875
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.07
    Marker Score: 8,014
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.06
    Marker Score: 19,401
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.03
    Marker Score: 125,049
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.01
    Marker Score: 1,118
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.98
    Marker Score: 1,185
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.95
    Marker Score: 34,599
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.95
    Marker Score: 2,149
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.94
    Marker Score: 7,915
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.94
    Marker Score: 5,541
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.92
    Marker Score: 6,837
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.88
    Marker Score: 17,841
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.86
    Marker Score: 3,130
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.84
    Marker Score: 583
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.82
    Marker Score: 3,506
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.82
    Marker Score: 952
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.81
    Marker Score: 896
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.8
    Marker Score: 15,501
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.78
    Marker Score: 1,916
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.76
    Marker Score: 18,153
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.72
    Marker Score: 908
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 1.72
    Marker Score: 1,212
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.69
    Marker Score: 4,821
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.68
    Marker Score: 9,027
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.67
    Marker Score: 455
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 1.66
    Marker Score: 598
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.65
    Marker Score: 36,818
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.63
    Marker Score: 2,035
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.62
    Marker Score: 10,443
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.62
    Marker Score: 1,216
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.62
    Marker Score: 550
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.6
    Marker Score: 1,384
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.58
    Marker Score: 25,333
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.57
    Marker Score: 1,389
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.56
    Marker Score: 2,414
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.56
    Marker Score: 1,929
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.53
    Marker Score: 1,635
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.52
    Marker Score: 1,172
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.52
    Marker Score: 850
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.52
    Marker Score: 568
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.52
    Marker Score: 6,542
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.51
    Marker Score: 4,956
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.47
    Marker Score: 425
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.45
    Marker Score: 1,249
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.43
    Marker Score: 426
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.43
    Marker Score: 518
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.41
    Marker Score: 533
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.41
    Marker Score: 977
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.39
    Marker Score: 1,485
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.36
    Marker Score: 661
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.36
    Marker Score: 1,539
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 1.34
    Marker Score: 695
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 1.32
    Marker Score: 7,074
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.31
    Marker Score: 334
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.31
    Marker Score: 340
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.29
    Marker Score: 848
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.27
    Marker Score: 469
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 1.27
    Marker Score: 1,249
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.22
    Marker Score: 1,731
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 1.21
    Marker Score: 4,072
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.21
    Marker Score: 1,274
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.21
    Marker Score: 1,460
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 1.21
    Marker Score: 654
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 1.2
    Marker Score: 1,194
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.17
    Marker Score: 1,115
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 1.14
    Marker Score: 1,609
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.13
    Marker Score: 1,203
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 1.13
    Marker Score: 2,364
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.13
    Marker Score: 38,036
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 1.12
    Marker Score: 957
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.12
    Marker Score: 628
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 1.11
    Marker Score: 666
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.09
    Marker Score: 440
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 1.08
    Marker Score: 437
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.07
    Marker Score: 987
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.07
    Marker Score: 36,542
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.06
    Marker Score: 340

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** DENND4A is a gene with a unique combination of characteristics that set it apart from other genes. Its expression is highly specific, with notable presence in anterior lens cells, lens epithelial cells, and various types of neurons. The gene's involvement in guanyl-nucleotide exchange factor activity and membrane trafficking suggests its role in regulating cellular signaling pathways. Additionally, DENND4A's association with DNA-templated transcription implies its potential involvement in gene regulation and transcriptional control. **Pathways and Functions:** DENND4A's involvement in various cellular pathways underscores its multifaceted role in maintaining cellular homeostasis. The gene's participation in guanyl-nucleotide exchange factor activity, membrane trafficking, and DNA-templated transcription positions it at the intersection of several key cellular processes. Specifically, DENND4A's role in regulating guanyl-nucleotide exchange factor activity suggests its involvement in cellular signaling pathways, while its association with membrane trafficking implies its role in regulating the movement of vesicles and organelles. Furthermore, DENND4A's involvement in DNA-templated transcription positions it as a potential regulator of gene expression. **Key Pathways:** 1. **Cytoplasmic Vesicle:** DENND4A's involvement in membrane trafficking and guanyl-nucleotide exchange factor activity positions it as a key regulator of cytoplasmic vesicle formation and function. 2. **Cytosol:** The gene's expression in various types of cells, including neurons and immune cells, underscores its role in cytosolic processes. 3. **DNA Binding:** DENND4A's association with DNA-templated transcription suggests its potential involvement in regulating gene expression. 4. **Rab Regulation of Trafficking:** The gene's involvement in membrane trafficking and guanyl-nucleotide exchange factor activity positions it as a key regulator of Rab-mediated trafficking pathways. **Clinically Significant:** DENND4A's involvement in various cellular processes makes it a potential candidate for involvement in various diseases. The gene's expression in lens cells and neurons suggests its potential role in ophthalmological and neurological disorders. Further research is needed to fully elucidate the clinical significance of DENND4A, but its multifaceted role in cellular homeostasis positions it as a promising candidate for further study. In conclusion, DENND4A is a gene of intricate immunological and cellular significance, with a unique combination of characteristics that set it apart from other genes. Its involvement in guanyl-nucleotide exchange factor activity, membrane trafficking, and DNA-templated transcription positions it at the intersection of several key cellular processes. Further research is needed to fully elucidate the clinical significance of DENND4A, but its multifaceted role in cellular homeostasis makes it a promising candidate for further study.

Genular Protein ID: 3185329067

Symbol: MYCPP_HUMAN

Name: C-myc promoter-binding protein

UniProtKB Accession Codes:

Q7Z401 E7EPL3 Q14655 Q86T77 Q8IVX2 Q8NB93

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 7 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 3 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SAM 1 SMART 3 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12906859

Title: Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges.

PubMed ID: 12906859

DOI: 10.1016/s0888-7543(03)00103-4

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 8056341

Title: Cloning of a cDNA encoding a human protein which binds a sequence in the c-myc gene similar to the interferon-stimulated response element.

PubMed ID: 8056341

DOI: 10.1016/0378-1119(94)90018-3

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20937701

Title: Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

PubMed ID: 20937701

DOI: 10.1083/jcb.201008051

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1863
  • Mass: 209244
  • Checksum: 7432EEC9DB9711E6
  • Sequence:
    • MIEDKGPRVA DYFVVAGLTD VSKPLEEEIH FNDACHKVAK PKEPITDVSV IIKSLGEEVP 
QDYICIDVTP TGLSADLNNG SLVGPQIYLC YRRGRDKPPL TDLGVLYDWK ERLKQGCEII 
QSTPYGRPAN ISGSTSSQRI YITYRRASEN MTQNTLAVTD ICIIIPSKGE SPPHTFCKVD 
KNLNNSMWGS AVYLCYKKSV AKTNTVSYKA GLICRYPQED YESFSLPESV PLFCLPMGAT 
IECWPSNSKY PLPVFSTFVL TGASAEKVYG AAIQFYEPYS EENLTEKQRL LLGLTSADGK 
SDSSKTIHTN KCICLLSHWP FFDAFRKFLT FLYRYSISGP HVLPIEKHIS HFMHKVPFPS 
PQRPRILVQL SPHDNLILSQ PVSSPLPLSG GKFSTLLQNL GPENAVTLLV FAVTEHKILI 
HSLRPSVLTS VTEALVSMIF PFHWPCPYVP LCPLALADVL SAPCPFIVGI DSRYFDLYDP 
PPDVSCVDVD TNTISQIGDK KNVAWKILPK KPCKNLMNTL NNLHQQLAKL QQRPRDDGLM 
DLAINDYDFN SGKRLHMIDL EIQEAFLFFM ASILKGYRSY LRPITQAPSE TATDAASLFA 
LQAFLRSRDR SHQKFYNMMT KTQMFIRFIE ECSFVSDKDA SLAFFDDCVD KVDMDKSGEV 
RLIELDESFK SEHTVFVTPP EIPHLPNGEE PPLQYSYNGF PVLRNNLFER PEGFLQAKKN 
KLPSKSSSPN SPLPMFRRTK QEIKSAHKIA KRYSSIPQMW SRCLLRHCYG LWFICLPAYV 
KVCHSKVRAL KTAYDVLKKM QSKKMDPPDE VCYRILMQLC GQYDQPVLAV RVLFEMQKAG 
IDPNAITYGY YNKAVLESTW PSRSRSGYFL WTKVRNVVLG VTQFKRALKK HAHLSQTTLS 
GGQSDLGYNS LSKDEVRRGD TSTEDIQEEK DKKGSDCSSL SESESTKGSA DCLPKLSYQN 
SSSIVRLTGT SNNSAGKISG ESMESTPELL LISSLEDTNE TRNIQSRCFR KRHKSDNETN 
LQQQVVWGNR NRNLSGGVLM GFMLNRINQE ATPGDIVEKL GADAKILSNV ISKSTRPNTL 
DIGKPPLRSK RDSLEKESSD DDTPFDGSNY LADKVDSPVI FDLEDLDSET DVSKAGCVAT 
QNPKRIQRMN SSFSVKPFEK TDVATGFDPL SLLVAETEQQ QKEEEEEDED DSKSISTPSA 
RRDLAEEIVM YMNNMSSPLT SRTPSIDLQR ACDDKLNKKS PPLVKACRRS SLPPNSPKPV 
RLTKSKSYTK SEEKPRDRLW SSPAFSPTCP FREESQDTLT HSSPSFNLDT LLVPKLDVLR 
NSMFTAGKGV AEKASKWYSR FTMYTTSSKD QSSDRTSLSS VGAQDSESTS LTDEDVCHEL 
EGPISSQETS ATSGTKRIDL SRISLESSAS LEGSLSKFAL PGKSEVTSSF NASNTNIFQN 
YAMEVLISSC SRCRTCDCLV HDEEIMAGWT ADDSNLNTTC PFCGNIFLPF LNIEIRDLRR 
PGRYFLKSSP STENMHFPSS ISSQTRQSCI STSASGLDTS ALSVQGNFDL NSKSKLQENF 
CTRSIQIPAN RSKTAMSKCP IFPMARSIST SGPLDKEDTG RQKLISTGSL PATLQGATDS 
LGLEWHLPSP DPVTVPYLSP LVVWKELESL LENEGDHAIT VADFVDHHPI VFWNLVWYFR 
RLDLPSNLPG LILSSEHCNK YSKIPRHCMS EDSKYVLIQM LWDNMKLHQD PGQPLYILWN 
AHTQKYPMVH LLQKSDNSFN QELLKSMVKS IKMNDVYGPM SQILETLNKC PHFKRQRSLY 
REILFLSLVA LGRENIDIDA FDKEYKMAYD RLTPSQVKST HNCDRPPSTG VMECRKTFGE 
PYL

Genular Protein ID: 1017280398

Symbol: A0A7I2RAZ6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A7I2RAZ6

Database IDs:

ARBA 1 Bgee 1 CTD 1 EMBL 1 EPD 1 Ensembl 2 GO 2 Gene3D 3 GeneTree 1 HGNC 1 InterPro 8 MANE-Select 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 Proteomes 2 RefSeq 4 SAM 1 SMART 3 SMR 1

Citations:

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

Sequence Information:

  • Length: 1907
  • Mass: 213775
  • Checksum: D2F26AB43ED71E3D
  • Sequence:
    • MIEDKGPRVA DYFVVAGLTD VSKPLEEEIH FNDACHKVAK PKEPITDVSV IIKSLGEEVP 
QDYICIDVTP TGLSADLNNG SLVGPQIYLC YRRGRDKPPL TDLGVLYDWK ERLKQGCEII 
QSTPYGRPAN ISGSTSSQRI YITYRRASEN MTQNTLAVTD ICIIIPSKGE SPPHTFCKVD 
KNLNNSMWGS AVYLCYKKSV AKTNTVSYKA GLICRYPQED YESFSLPESV PLFCLPMGAT 
IECWPSNSKY PLPVFSTFVL TGASAEKVYG AAIQFYEPYS EENLTEKQRL LLGLTSADGK 
SDSSKTIHTN KCICLLSHWP FFDAFRKFLT FLYRYSISGP HVLPIEKHIS HFMHKVPFPS 
PQRPRILVQL SPHDNLILSQ PVSSPLPLSG GKFSTLLQNL GPENAVTLLV FAVTEHKILI 
HSLRPSVLTS VTEALVSMIF PFHWPCPYVP LCPLALADVL SAPCPFIVGI DSRYFDLYDP 
PPDVSCVDVD TNTISQIGDK KNVAWKILPK KPCKNLMNTL NNLHQQLAKL QQRPRDDGLM 
DLAINDYDFN SGKRLHMIDL EIQEAFLFFM ASILKGYRSY LRPITQAPSE TATDAASLFA 
LQAFLRSRDR SHQKFYNMMT KTQMFIRFIE ECSFVSDKDA SLAFFDDCVD KVDMDKSGEV 
RLIELDESFK SEHTVFVTPP EIPHLPNGEE PPLQYSYNGF PVLRNNLFER PEGFLQAKKN 
KLPSKSSSPN SPLPMFRRTK QEIKSAHKIA KRYSSIPQMW SRCLLRHCYG LWFICLPAYV 
KVCHSKVRAL KTAYDVLKKM QSKKMDPPDE VCYRILMQLC GQYDQPVLAV RVLFEMQKAG 
IDPNAITYGY YNKAVLESTW PSRSRSGYFL WTKVRNVVLG VTQFKRALKK HAHLSQTTLS 
ADGSDLDAVS HGSMDSGHGT HTVEQAPFNT GLIKVYATDD RSSTGGQSDL GYNSLSKDEV 
RRGDTSTEDI QEEKDKKGSD CSSLSESEST KGSADCLPKL SYQNSSSIVR LTGTSNNSAG 
KISGESMEST PELLLISSLE DTNETRNIQS RCFRKRHKSD NETNLQQQVV WGNRNRNLSG 
GVLMGFMLNR INQEATPGDI VEKLGADAKI LSNVISKSTR PNTLDIGKPP LRSKRDSLEK 
ESSDDDTPFD GSNYLADKVD SPVIFDLEDL DSETDVSKAG CVATQNPKRI QRMNSSFSVK 
PFEKTDVATG FDPLSLLVAE TEQQQKEEEE EDEDDSKSIS TPSARRDLAE EIVMYMNNMS 
SPLTSRTPSI DLQRACDDKL NKKSPPLVKA CRRSSLPPNS PKPVRLTKSK SYTKSEEKPR 
DRLWSSPAFS PTCPFREESQ DTLTHSSPSF NLDTLLVPKL DVLRNSMFTA GKGVAEKASK 
WYSRFTMYTT SSKDQSSDRT SLSSVGAQDS ESTSLTDEDV CHELEGPISS QETSATSGTK 
RIDLSRISLE SSASLEGSLS KFALPGKSEV TSSFNASNTN IFQNYAMEVL ISSCSRCRTC 
DCLVHDEEIM AGWTADDSNL NTTCPFCGNI FLPFLNIEIR DLRRPGRYFL KSSPSTENMH 
FPSSISSQTR QSCISTSASG LDTSALSVQG NFDLNSKSKL QENFCTRSIQ IPANRSKTAM 
SKCPIFPMAR SISTSGPLDK EDTGRQKLIS TGSLPATLQG ATDSLGLEWH LPSPDPVTVP 
YLSPLVVWKE LESLLENEGD HAITVADFVD HHPIVFWNLV WYFRRLDLPS NLPGLILSSE 
HCNKYSKIPR HCMSEDSKYV LIQMLWDNMK LHQDPGQPLY ILWNAHTQKY PMVHLLQKSD 
NSFNQELLKS MVKSIKMNDV YGPMSQILET LNKCPHFKRQ RSLYREILFL SLVALGRENI 
DIDAFDKEYK MAYDRLTPSQ VKSTHNCDRP PSTGVMECRK TFGEPYL

Genular Protein ID: 620354536

Symbol: Q05C90_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q05C90

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 2 Gene3D 3 Genevisible 1 GenomeRNAi 1 InterPro 9 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 1 SAM 1 SMART 3

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 933
  • Mass: 105607
  • Checksum: 1EB75548645ACAD5
  • Sequence:
    • MIEDKGPRVA DYFVVAGLTD VSKPLEEEIH FNDACHKVAK PKEPITDVSV IIKSLGEEVP 
QDYICIDVTP TGLSADLNNG SLVGPQIYLC YRRGRDKPPL TDLGVLYDWK ERLKQGCEII 
QSTPYGRPAN ISGSTSSQRI YITYRRASEN MTQNTLAVTD ICIIIPSKGE SPPHTFCKVD 
KNLNNSMWGS AVYLCYKKSV AKTNTVSYKA GLICRYPQED YESFSLPESV PLFCLPMGAT 
IECWPSNSKY PLPVFSTFVL TGASAEKVYG AAIQFYEPYS EENLTEKQRL LLGLTSADGK 
SDSSKTIHTN KCICLLSHWP FFDAFRKFLT FLYRYSISGP HVLPIEKHIS HFMHKVPFPS 
PQRPRILVQL SPHDNLILSQ PVSSPLPLSG GKFSTLLQNL GPENAVTLLV FAVTEHKILI 
HSLRPSVLTS VTEALVSMIF PFHWPCPYVP LCPLALADVL SAPCPFIVGI DSRYFDLYDP 
PPDVSCVDVD TNTISQIGDK KNVAWKILPK KPCKNLMNTL NNLHQQLAKL QQRPRDDGLM 
DLAINDYDFN SGKRLHMIDL EIQEAFLFFM ASILKGYRSY LRPITQAPSE TATDAASLFA 
LQAFLRSRDR SHQKFYNMMT KTQMFIRFIE ECSFVSDKDA SLAFFDDCVD KVDMDKSGEV 
RLIELDESFK SEHTVFVTPP EIPHLPNGEE PPLQYSYNGF PVLRNNLFER PEGFLQAKKN 
KLPSKSSSPN SPLPMFRRTK QEIKSAHKIA KRYSSIPQMW SRCLLRHCYG LWFICLPAYV 
KVCHSKVRAL KTAYDVLKKM QSKKMDPPDE VCYRILMQLC GQYDQPVLAV RVLFEMQKAG 
IDPNAITYGY YNKAVLESTW PSRSRSGYFL WTKVRNVVLG VTQFKRALKK HAHLSQTTLS 
GGQSDLGYNS LSKDEVRRGD TSTEDIQEEK KKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.