IRX5 | ENSG00000176842 | NCBI 10265

Details for: IRX5

Gene ID: 10265

Symbol: IRX5

Ensembl ID: ENSG00000176842

Description: iroquois homeobox 5

Associated with

Cell development
(GO:0048468)
Chromatin
(GO:0000785)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription factor binding
(GO:0140297)
Embryonic cranial skeleton morphogenesis
(GO:0048701)
Gonad development
(GO:0008406)
Neuron differentiation
(GO:0030182)
Nucleus
(GO:0005634)
Protein self-association
(GO:0043621)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to stimulus
(GO:0050896)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific double-stranded dna binding
(GO:1990837)
Visual perception
(GO:0007601)
Vitamin d binding
(GO:0005499)

Other Information

Proteins

Iroquois-class homeodomain protein IRX-5

Genular Protein ID: 3515416834

Symbol: IRX5_HUMAN

Name: Iroquois-class homeodomain protein IRX-5

UniProtKB Accession Codes:

P78411 H0YMS7 P78416 Q7Z2E1

Database IDs:

Citations:

PubMed ID: 10370142

Title: Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast.

PubMed ID: 10370142

DOI: 10.1007/s004410051316

PubMed ID: 18519790

Title: The iroquois homeobox gene 5 is regulated by 1,25-dihydroxyvitamin D3 in human prostate cancer and regulates apoptosis and the cell cycle in LNCaP prostate cancer cells.

PubMed ID: 18519790

DOI: 10.1158/1078-0432.ccr-07-4649

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 22581230

Title: Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1.

PubMed ID: 22581230

DOI: 10.1038/ng.2259

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

Sequence Information:

Length: 483
Mass: 50361
Checksum: 12E9397924EB5E6E
Sequence:

MSYPQGYLYQ PSASLALYSC PAYSTSVISG PRTDELGRSS SGSAFSPYAG STAFTAPSPG 
YNSHLQYGAD PAAAAAAAFS SYVGSPYDHT PGMAGSLGYH PYAAPLGSYP YGDPAYRKNA 
TRDATATLKA WLNEHRKNPY PTKGEKIMLA IITKMTLTQV STWFANARRR LKKENKMTWT 
PRNRSEDEEE EENIDLEKND EDEPQKPEDK GDPEGPEAGG AEQKAASGCE RLQGPPTPAG 
KETEGSLSDS DFKEPPSEGR LDALQGPPRT GGPSPAGPAA ARLAEDPAPH YPAGAPAPGP 
HPAAGEVPPG PGGPSVIHSP PPPPPPAVLA KPKLWSLAEI ATSSDKVKDG GGGNEGSPCP 
PCPGPIAGQA LGGSRASPAP APSRSPSAQC PFPGGTVLSR PLYYTAPFYP GYTNYGSFGH 
LHGHPGPGPG PTTGPGSHFN GLNQTVLNRA DALAKDPKML RSQSQLDLCK DSPYELKKGM 
SDI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: IRX5

Associated with

Other Information

Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast. PubMed ID: 10370142

The iroquois homeobox gene 5 is regulated by 1,25-dihydroxyvitamin D3 in human prostate cancer and regulates apoptosis and the cell cycle in LNCaP prostate cancer cells. PubMed ID: 18519790

The sequence and analysis of duplication-rich human chromosome 16. PubMed ID: 15616553