Details for: AKAP8

Gene ID: 10270

Symbol: AKAP8

Ensembl ID: ENSG00000105127

Description: A-kinase anchoring protein 8

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.17
    Marker Score: 2,751
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.11
    Marker Score: 17,430
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.06
    Marker Score: 1,642
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 1.02
    Marker Score: 1,012
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1
    Marker Score: 8,593
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,680
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,905
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,390
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.95
    Marker Score: 9,851
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.95
    Marker Score: 9,042
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,395
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.92
    Marker Score: 56,800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.92
    Marker Score: 972
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.92
    Marker Score: 475
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.92
    Marker Score: 2,262
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.91
    Marker Score: 1,926
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.91
    Marker Score: 430
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.91
    Marker Score: 834
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2,693
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.89
    Marker Score: 1,311
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.88
    Marker Score: 970
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,292
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 0.86
    Marker Score: 519
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.85
    Marker Score: 307
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.84
    Marker Score: 559
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.84
    Marker Score: 4,766
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.82
    Marker Score: 1,335
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.82
    Marker Score: 557
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 0.82
    Marker Score: 289
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.82
    Marker Score: 30,127
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.8
    Marker Score: 3,152
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.8
    Marker Score: 251
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.79
    Marker Score: 1,056
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.78
    Marker Score: 379
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.78
    Marker Score: 312
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 0.78
    Marker Score: 765
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 0.77
    Marker Score: 7,249
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.76
    Marker Score: 582
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.75
    Marker Score: 973
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.75
    Marker Score: 997
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.75
    Marker Score: 219
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.74
    Marker Score: 311
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.74
    Marker Score: 2,869
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.74
    Marker Score: 300
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.73
    Marker Score: 1,486
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.72
    Marker Score: 27,514
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.72
    Marker Score: 292
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.72
    Marker Score: 779
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.72
    Marker Score: 15,365
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.72
    Marker Score: 231
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.72
    Marker Score: 354
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.72
    Marker Score: 430
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.71
    Marker Score: 1,373
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.71
    Marker Score: 863
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.71
    Marker Score: 369
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7
    Marker Score: 2,947
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.7
    Marker Score: 807
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.69
    Marker Score: 13,749
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.69
    Marker Score: 2,880
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 0.69
    Marker Score: 10,280
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.69
    Marker Score: 2,443
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 0.69
    Marker Score: 643
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 175
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.68
    Marker Score: 436
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 0.68
    Marker Score: 235
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 0.68
    Marker Score: 988
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.68
    Marker Score: 4,080
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 0.68
    Marker Score: 5,193
  • Cell Name: NKp44-positive group 3 innate lymphoid cell, human (CL0001079)
    Fold Change: 0.67
    Marker Score: 152
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.67
    Marker Score: 271
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.67
    Marker Score: 247
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.66
    Marker Score: 2,283
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.66
    Marker Score: 606
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.66
    Marker Score: 439
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.66
    Marker Score: 452
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 0.66
    Marker Score: 148
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 0.66
    Marker Score: 2,746
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.66
    Marker Score: 145
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.66
    Marker Score: 229
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.66
    Marker Score: 313
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.66
    Marker Score: 2,670
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.65
    Marker Score: 1,486
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.65
    Marker Score: 206
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.65
    Marker Score: 407
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.65
    Marker Score: 1,426
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.65
    Marker Score: 155
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.65
    Marker Score: 225
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.64
    Marker Score: 6,521
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.64
    Marker Score: 2,380
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.64
    Marker Score: 802
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.63
    Marker Score: 371
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.63
    Marker Score: 35,237
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.63
    Marker Score: 289
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.63
    Marker Score: 458
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 0.63
    Marker Score: 630
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.62
    Marker Score: 426
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 0.62
    Marker Score: 269
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 0.62
    Marker Score: 673
  • Cell Name: NKp44-negative group 3 innate lymphoid cell, human (CL0001080)
    Fold Change: 0.62
    Marker Score: 137
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.62
    Marker Score: 537

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** AKAP8 is a member of the A-kinase anchoring protein (AKAP) family, which plays a crucial role in anchoring protein kinase A (PKA) to specific subcellular compartments. This anchoring mechanism allows PKA to regulate a wide range of cellular processes, including cell cycle progression, gene expression, and immune response. AKAP8 is specifically expressed in various cell types, including kidney proximal straight tubule epithelial cells, cardiac muscle myoblasts, and cerebral cortex GABAergic interneurons. **Pathways and Functions:** AKAP8 is involved in several key signaling pathways, including: 1. **Cell cycle regulation**: AKAP8 regulates the G2/M phase transition by modulating the activity of PKA, which in turn phosphorylates and activates cyclin-dependent kinases (CDKs). 2. **Immune response**: AKAP8 plays a crucial role in the cellular response to lipopolysaccharide (LPS) and prostaglandin E2 (PGE2) by regulating the activity of PKA, which in turn modulates the expression of inflammatory genes. 3. **Signal transduction**: AKAP8 regulates the activity of PKA, which in turn phosphorylates and activates various downstream targets, including protein kinases and transcription factors. **Clinical Significance:** AKAP8 has been implicated in various diseases, including: 1. **Immune disorders**: AKAP8 has been shown to play a crucial role in the regulation of immune response, and its dysregulation has been implicated in autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis. 2. **Cancer**: AKAP8 has been shown to regulate cell cycle progression and apoptosis, and its dysregulation has been implicated in various types of cancer, including breast, lung, and colon cancer. 3. **Neurological disorders**: AKAP8 has been implicated in the regulation of neuronal signaling and has been shown to play a role in various neurological disorders, including Alzheimer's disease and Parkinson's disease. In conclusion, AKAP8 is a multifunctional protein that plays a crucial role in various cellular processes, including cell cycle regulation, immune response, and signal transduction. Its dysregulation has been implicated in various diseases, and further research is needed to fully understand its role in human disease. **Significant Expression in Various Cell Types:** * Kidney proximal straight tubule epithelial cells * Cardiac muscle myoblasts * L5 extratelencephalic projecting glutamatergic cortical neuron * Type B pancreatic cell * L6b glutamatergic cortical neuron * Cerebral cortex GABAergic interneuron * Forebrain radial glial cell * Absorptive cell * Dopaminergic neuron * Corticothalamic-projecting glutamatergic cortical neuron **Proteins:** * AKAP8_HUMAN (A-kinase anchor protein 8) This summary highlights the key characteristics, pathways, and functions of AKAP8, as well as its significant expression in various cell types and its clinical significance. As an expert immunologist, I hope that this summary provides a comprehensive overview of the role of AKAP8 in human disease.

Genular Protein ID: 1669677098

Symbol: AKAP8_HUMAN

Name: A-kinase anchor protein 8

UniProtKB Accession Codes:

O43823

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 EMBL 2 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 23 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SAM 1 SIGNOR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 3 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9473338

Title: Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95.

PubMed ID: 9473338

DOI: 10.1006/excr.1997.3855

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 10601332

Title: The A-kinase-anchoring protein AKAP95 is a multivalent protein with a key role in chromatin condensation at mitosis.

PubMed ID: 10601332

DOI: 10.1083/jcb.147.6.1167

PubMed ID: 10791967

Title: A kinase-anchoring protein (AKAP)95 recruits human chromosome-associated protein (hCAP)-D2/Eg7 for chromosome condensation in mitotic extract.

PubMed ID: 10791967

DOI: 10.1083/jcb.149.3.531

PubMed ID: 10764601

Title: Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding.

PubMed ID: 10764601

DOI: 10.1006/jmbi.2000.3662

PubMed ID: 11591814

Title: Regulation of anchoring of the RIIalpha regulatory subunit of PKA to AKAP95 by threonine phosphorylation of RIIalpha: implications for chromosome dynamics at mitosis.

PubMed ID: 11591814

DOI: 10.1242/jcs.114.18.3255

PubMed ID: 11964380

Title: Distinct but overlapping domains of AKAP95 are implicated in chromosome condensation and condensin targeting.

PubMed ID: 11964380

DOI: 10.1093/embo-reports/kvf089

PubMed ID: 12740381

Title: Protein kinase A-anchoring protein AKAP95 interacts with MCM2, a regulator of DNA replication.

PubMed ID: 12740381

DOI: 10.1074/jbc.m300765200

PubMed ID: 14641107

Title: A novel partner for D-type cyclins: protein kinase A-anchoring protein AKAP95.

PubMed ID: 14641107

DOI: 10.1042/bj20031765

PubMed ID: 15470020

Title: A-kinase anchoring proteins interact with phosphodiesterases in T lymphocyte cell lines.

PubMed ID: 15470020

DOI: 10.4049/jimmunol.173.8.4806

PubMed ID: 16227597

Title: A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association.

PubMed ID: 16227597

DOI: 10.1128/mcb.25.21.9469-9477.2005

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16980585

Title: A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity.

PubMed ID: 16980585

DOI: 10.1101/gad.1455006

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19277197

Title: A-kinase anchoring in dendritic cells is required for antigen presentation.

PubMed ID: 19277197

DOI: 10.1371/journal.pone.0004807

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22130794

Title: Localization and retention of p90 ribosomal S6 kinase 1 in the nucleus: implications for its function.

PubMed ID: 22130794

DOI: 10.1091/mbc.e11-07-0658

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23995757

Title: Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95.

PubMed ID: 23995757

DOI: 10.1038/nsmb.2656

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25770215

Title: Role for tyrosine phosphorylation of a-kinase anchoring protein 8 (AKAP8) in its dissociation from chromatin and the nuclear matrix.

PubMed ID: 25770215

DOI: 10.1074/jbc.m115.643882

PubMed ID: 26683827

Title: A-kinase anchoring protein AKAP95 is a novel regulator of ribosomal RNA synthesis.

PubMed ID: 26683827

DOI: 10.1111/febs.13630

PubMed ID: 26880274

Title: Dynamic changes in protein interaction between AKAP95 and Cx43 during cell cycle progression of A549 cells.

PubMed ID: 26880274

DOI: 10.1038/srep21224

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 692
  • Mass: 76108
  • Checksum: CBCD5F014FD94B66
  • Sequence:
    • MDQGYGGYGA WSAGPANTQG AYGTGVASWQ GYENYNYYGA QNTSVTTGAT YSYGPASWEA 
AKANDGGLAA GAPAMHMASY GPEPCTDNSD SLIAKINQRL DMMSKEGGRG GSGGGGEGIQ 
DRESSFRFQP FESYDSRPCL PEHNPYRPSY SYDYEFDLGS DRNGSFGGQY SECRDPARER 
GSLDGFMRGR GQGRFQDRSN PGTFMRSDPF VPPAASSEPL STPWNELNYV GGRGLGGPSP 
SRPPPSLFSQ SMAPDYGVMG MQGAGGYDST MPYGCGRSQP RMRDRDRPKR RGFDRFGPDG 
TGRKRKQFQL YEEPDTKLAR VDSEGDFSEN DDAAGDFRSG DEEFKGEDEL CDSGRQRGEK 
EDEDEDVKKR REKQRRRDRT RDRAADRIQF ACSVCKFRSF DDEEIQKHLQ SKFHKETLRF 
ISTKLPDKTV EFLQEYIVNR NKKIEKRRQE LMEKETAKPK PDPFKGIGQE HFFKKIEAAH 
CLACDMLIPA QPQLLQRHLH SVDHNHNRRL AAEQFKKTSL HVAKSVLNNR HIVKMLEKYL 
KGEDPFTSET VDPEMEGDDN LGGEDKKETP EEVAADVLAE VITAAVRAVD GEGAPAPESS 
GEPAEDEGPT DTAEAGSDPQ AEQLLEEQVP CGTAHEKGVP KARSEAAEAG NGAETMAAEA 
ESAQTRVAPA PAAADAEVEQ TDAESKDAVP TE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.