Details for: AKAP8
Associated with
Other Information
Genular Protein ID: 1669677098
Symbol: AKAP8_HUMAN
Name: A-kinase anchor protein 8
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9473338
Title: Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95.
PubMed ID: 9473338
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 10601332
Title: The A-kinase-anchoring protein AKAP95 is a multivalent protein with a key role in chromatin condensation at mitosis.
PubMed ID: 10601332
PubMed ID: 10791967
Title: A kinase-anchoring protein (AKAP)95 recruits human chromosome-associated protein (hCAP)-D2/Eg7 for chromosome condensation in mitotic extract.
PubMed ID: 10791967
PubMed ID: 10764601
Title: Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding.
PubMed ID: 10764601
PubMed ID: 11591814
Title: Regulation of anchoring of the RIIalpha regulatory subunit of PKA to AKAP95 by threonine phosphorylation of RIIalpha: implications for chromosome dynamics at mitosis.
PubMed ID: 11591814
PubMed ID: 11964380
Title: Distinct but overlapping domains of AKAP95 are implicated in chromosome condensation and condensin targeting.
PubMed ID: 11964380
PubMed ID: 12740381
Title: Protein kinase A-anchoring protein AKAP95 interacts with MCM2, a regulator of DNA replication.
PubMed ID: 12740381
PubMed ID: 14641107
Title: A novel partner for D-type cyclins: protein kinase A-anchoring protein AKAP95.
PubMed ID: 14641107
DOI: 10.1042/bj20031765
PubMed ID: 15470020
Title: A-kinase anchoring proteins interact with phosphodiesterases in T lymphocyte cell lines.
PubMed ID: 15470020
PubMed ID: 16227597
Title: A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association.
PubMed ID: 16227597
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16980585
Title: A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity.
PubMed ID: 16980585
DOI: 10.1101/gad.1455006
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19277197
Title: A-kinase anchoring in dendritic cells is required for antigen presentation.
PubMed ID: 19277197
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22130794
Title: Localization and retention of p90 ribosomal S6 kinase 1 in the nucleus: implications for its function.
PubMed ID: 22130794
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23995757
Title: Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95.
PubMed ID: 23995757
DOI: 10.1038/nsmb.2656
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 25770215
Title: Role for tyrosine phosphorylation of a-kinase anchoring protein 8 (AKAP8) in its dissociation from chromatin and the nuclear matrix.
PubMed ID: 25770215
PubMed ID: 26683827
Title: A-kinase anchoring protein AKAP95 is a novel regulator of ribosomal RNA synthesis.
PubMed ID: 26683827
DOI: 10.1111/febs.13630
PubMed ID: 26880274
Title: Dynamic changes in protein interaction between AKAP95 and Cx43 during cell cycle progression of A549 cells.
PubMed ID: 26880274
DOI: 10.1038/srep21224
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 692
- Mass: 76108
- Checksum: CBCD5F014FD94B66
- Sequence:
MDQGYGGYGA WSAGPANTQG AYGTGVASWQ GYENYNYYGA QNTSVTTGAT YSYGPASWEA AKANDGGLAA GAPAMHMASY GPEPCTDNSD SLIAKINQRL DMMSKEGGRG GSGGGGEGIQ DRESSFRFQP FESYDSRPCL PEHNPYRPSY SYDYEFDLGS DRNGSFGGQY SECRDPARER GSLDGFMRGR GQGRFQDRSN PGTFMRSDPF VPPAASSEPL STPWNELNYV GGRGLGGPSP SRPPPSLFSQ SMAPDYGVMG MQGAGGYDST MPYGCGRSQP RMRDRDRPKR RGFDRFGPDG TGRKRKQFQL YEEPDTKLAR VDSEGDFSEN DDAAGDFRSG DEEFKGEDEL CDSGRQRGEK EDEDEDVKKR REKQRRRDRT RDRAADRIQF ACSVCKFRSF DDEEIQKHLQ SKFHKETLRF ISTKLPDKTV EFLQEYIVNR NKKIEKRRQE LMEKETAKPK PDPFKGIGQE HFFKKIEAAH CLACDMLIPA QPQLLQRHLH SVDHNHNRRL AAEQFKKTSL HVAKSVLNNR HIVKMLEKYL KGEDPFTSET VDPEMEGDDN LGGEDKKETP EEVAADVLAE VITAAVRAVD GEGAPAPESS GEPAEDEGPT DTAEAGSDPQ AEQLLEEQVP CGTAHEKGVP KARSEAAEAG NGAETMAAEA ESAQTRVAPA PAAADAEVEQ TDAESKDAVP TE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.