Details for: FSTL3

Gene ID: 10272

Symbol: FSTL3

Ensembl ID: ENSG00000070404

Description: follistatin like 3

Associated with

Other Information

Genular Protein ID: 3902826504

Symbol: FSTL3_HUMAN

Name: Follistatin-related protein 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9671416

Title: FLRG (follistatin-related gene), a new target of chromosomal rearrangement in malignant blood disorders.

PubMed ID: 9671416

DOI: 10.1038/sj.onc.1201807

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 11459787

Title: Human follistatin-related protein: a structural homologue of follistatin with nuclear localization.

PubMed ID: 11459787

DOI: 10.1210/endo.142.8.8319

PubMed ID: 11948405

Title: Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function.

PubMed ID: 11948405

DOI: 10.1038/sj.onc.1205294

PubMed ID: 12697670

Title: Differential binding and neutralization of activins A and B by follistatin and follistatin like-3 (FSTL-3/FSRP/FLRG).

PubMed ID: 12697670

DOI: 10.1210/en.2002-0203

PubMed ID: 12970321

Title: Follistatin-related gene (FLRG) expression in human endometrium: sex steroid hormones regulate the expression of FLRG in cultured human endometrial stromal cells.

PubMed ID: 12970321

DOI: 10.1210/jc.2002-021758

PubMed ID: 15451575

Title: FLRG, member of the follistatin family, a new player in hematopoiesis.

PubMed ID: 15451575

DOI: 10.1016/j.mce.2004.07.009

PubMed ID: 15574124

Title: FLRG, a new ADAM12-associated protein, modulates osteoclast differentiation.

PubMed ID: 15574124

DOI: 10.1042/bc20040506

PubMed ID: 16150905

Title: Differential biosynthesis and intracellular transport of follistatin isoforms and follistatin-like-3.

PubMed ID: 16150905

DOI: 10.1210/en.2005-0833

PubMed ID: 16336961

Title: A novel role for fibronectin type I domain in the regulation of human hematopoietic cell adhesiveness through binding to follistatin domains of FLRG and follistatin.

PubMed ID: 16336961

DOI: 10.1016/j.yexcr.2005.11.006

PubMed ID: 17868029

Title: AF10-dependent transcription is enhanced by its interaction with FLRG.

PubMed ID: 17868029

DOI: 10.1042/bc20060131

PubMed ID: 17878677

Title: Characterization of follistatin-related gene as a negative regulatory factor for activin family members during mouse heart development.

PubMed ID: 17878677

DOI: 10.2152/jmi.54.276

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 18768470

Title: The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity.

PubMed ID: 18768470

DOI: 10.1074/jbc.m801266200

PubMed ID: 22052913

Title: Structure of myostatin.follistatin-like 3: N-terminal domains of follistatin-type molecules exhibit alternate modes of binding.

PubMed ID: 22052913

DOI: 10.1074/jbc.m111.270801

Sequence Information:

  • Length: 263
  • Mass: 27663
  • Checksum: 6A9AB86ADD4FD09C
  • Sequence:
  • MRPGAPGPLW PLPWGALAWA VGFVSSMGSG NPAPGGVCWL QQGQEATCSL VLQTDVTRAE 
    CCASGNIDTA WSNLTHPGNK INLLGFLGLV HCLPCKDSCD GVECGPGKAC RMLGGRPRCE 
    CAPDCSGLPA RLQVCGSDGA TYRDECELRA ARCRGHPDLS VMYRGRCRKS CEHVVCPRPQ 
    SCVVDQTGSA HCVVCRAAPC PVPSSPGQEL CGNNNVTYIS SCHMRQATCF LGRSIGVRHA 
    GSCAGTPEEP PGGESAEEEE NFV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.