Details for: STAG1

Gene ID: 10274

Symbol: STAG1

Ensembl ID: ENSG00000118007

Description: STAG1 cohesin complex component

Associated with

Other Information

Genular Protein ID: 3625127246

Symbol: STAG1_HUMAN

Name: Cohesin subunit SA-1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9305759

Title: SA-1, a nuclear protein encoded by one member of a novel gene family: molecular cloning and detection in hemopoietic organs.

PubMed ID: 9305759

DOI: 10.1016/s0378-1119(97)00121-2

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11076961

Title: Characterization of vertebrate cohesin complexes and their regulation in prophase.

PubMed ID: 11076961

DOI: 10.1083/jcb.151.4.749

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22628566

Title: In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex.

PubMed ID: 22628566

DOI: 10.1073/pnas.1206840109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28119487

Title: STAG1 mutations cause a novel cohesinopathy characterised by unspecific syndromic intellectual disability.

PubMed ID: 28119487

DOI: 10.1136/jmedgenet-2016-104468

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 32409525

Title: Cryo-EM structure of the human cohesin-NIPBL-DNA complex.

PubMed ID: 32409525

DOI: 10.1126/science.abb0981

PubMed ID: 30158690

Title: Clinical exome sequencing reveals locus heterogeneity and phenotypic variability of cohesinopathies.

PubMed ID: 30158690

DOI: 10.1038/s41436-018-0085-6

Sequence Information:

  • Length: 1258
  • Mass: 144427
  • Checksum: FAF911998EC52179
  • Sequence:
  • MITSELPVLQ DSTNETTAHS DAGSELEETE VKGKRKRGRP GRPPSTNKKP RKSPGEKSRI 
    EAGIRGAGRG RANGHPQQNG EGEPVTLFEV VKLGKSAMQS VVDDWIESYK QDRDIALLDL 
    INFFIQCSGC RGTVRIEMFR NMQNAEIIRK MTEEFDEDSG DYPLTMPGPQ WKKFRSNFCE 
    FIGVLIRQCQ YSIIYDEYMM DTVISLLTGL SDSQVRAFRH TSTLAAMKLM TALVNVALNL 
    SIHQDNTQRQ YEAERNKMIG KRANERLELL LQKRKELQEN QDEIENMMNS IFKGIFVHRY 
    RDAIAEIRAI CIEEIGVWMK MYSDAFLNDS YLKYVGWTLH DRQGEVRLKC LKALQSLYTN 
    RELFPKLELF TNRFKDRIVS MTLDKEYDVA VEAIRLVTLI LHGSEEALSN EDCENVYHLV 
    YSAHRPVAVA AGEFLHKKLF SRHDPQAEEA LAKRRGRNSP NGNLIRMLVL FFLESELHEH 
    AAYLVDSLWE SSQELLKDWE CMTELLLEEP VQGEEAMSDR QESALIELMV CTIRQAAEAH 
    PPVGRGTGKR VLTAKERKTQ IDDRNKLTEH FIITLPMLLS KYSADAEKVA NLLQIPQYFD 
    LEIYSTGRME KHLDALLKQI KFVVEKHVES DVLEACSKTY SILCSEEYTI QNRVDIARSQ 
    LIDEFVDRFN HSVEDLLQEG EEADDDDIYN VLSTLKRLTS FHNAHDLTKW DLFGNCYRLL 
    KTGIEHGAMP EQIVVQALQC SHYSILWQLV KITDGSPSKE DLLVLRKTVK SFLAVCQQCL 
    SNVNTPVKEQ AFMLLCDLLM IFSHQLMTGG REGLQPLVFN PDTGLQSELL SFVMDHVFID 
    QDEENQSMEG DEEDEANKIE ALHKRRNLLA AFSKLIIYDI VDMHAAADIF KHYMKYYNDY 
    GDIIKETLSK TRQIDKIQCA KTLILSLQQL FNELVQEQGP NLDRTSAHVS GIKELARRFA 
    LTFGLDQIKT REAVATLHKD GIEFAFKYQN QKGQEYPPPN LAFLEVLSEF SSKLLRQDKK 
    TVHSYLEKFL TEQMMERRED VWLPLISYRN SLVTGGEDDR MSVNSGSSSS KTSSVRNKKG 
    RPPLHKKRVE DESLDNTWLN RTDTMIQTPG PLPAPQLTST VLRENSRPMG DQIQEPESEH 
    GSEPDFLHNP QMQISWLGQP KLEDLNRKDR TGMNYMKVRT GVRHAVRGLM EEDAEPIFED 
    VMMSSRSQLE DMNEEFEDTM VIDLPPSRNR RERAELRPDF FDSAAIIEDD SGFGMPMF

Genular Protein ID: 2103842381

Symbol: Q4LE48_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 1275
  • Mass: 146339
  • Checksum: 670E3573E6ACBE74
  • Sequence:
  • VVQHLIILLH CERTSPAMIT SELPVLQDST NETTAHSDAG SELEETEVKG KRKRGRPGRP 
    PSTNKKPRKS PGEKSRIEAG IRGAGRGRAN GHPQQNGEGE PVTLFEVVKL GKSAMQSVVD 
    DWIESYKQDR DIALLDLINF FIQCSGCRGT VRIEMFRNMQ NAEIIRKMTE EFDEDSGDYP 
    LTMPGPQWKK FRSNFCEFIG VLIRQCQYSI IYDEYMMDTV ISLLTGLSDS QVRAFRHTST 
    LAAMKLMTAL VNVALNLSIH QDNTQRQYEA ERNKMIGKRA NERLELLLQK RKELQENQDE 
    IENMMNSIFK GIFVHRYRDA IAEIRAICIE EIGVWMKMYS DAFLNDSYLK YVGWTLHDRQ 
    GEVRLKCLKA LQSLYTNREL FPKLELFTNR FKDRIVSMTL DKEYDVAVEA IRLVTLILHG 
    SEEALSNEDC ENVYHLVYSA HRPVAVAAGE FLHKKLFSRH DPQAEEALAK RRGRNSPNGN 
    LIRMLVLFFL ESELHEHAAY LVDSLWESSQ ELLKDWECMT ELLLEEPVQG EEAMSDRQES 
    ALIELMVCTI RQAAEAHPPV GRGTGKRVLT AKERKTQIDD RNKLTEHFII TLPMLLSKYS 
    ADAEKVANLL QIPQYFDLEI YSTGRMEKHL DALLKQIKFV VEKHVESDVL EACSKTYSIL 
    CSEEYTIQNR VDIARSQLID EFVDRFNHSV EDLLQEGEEA DDDDIYNVLS TLKRLTSFHN 
    AHDLTKWDLF GNCYRLLKTG IEHGAMPEQI VVQALQCSHY SILWQLVKIT DGSPSKEDLL 
    VLRKTVKSFL AVCQQCLSNV NTPVKEQAFM LLCDLLMIFS HQLMTGGREG LQPLVFNPDT 
    GLQSELLSFV MDHVFIDQDE ENQSMEGDEE DEANKIEALH KRRNLLAAFS KLIIYDIVDM 
    HAAADIFKHY MKYYNDYGDI IKETLSKTRQ IDKIQCAKTL ILSLQQLFNE LVQEQGPNLD 
    RTSAHVSGIK ELARRFALTF GLDQIKTREA VATLHKDGIE FAFKYQNQKG QEYPPPNLAF 
    LEVLSEFSSK LLRQDKKTVH SYLEKFLTEQ MMERREDVWL PLISYRNSLV TGGEDDRMSV 
    NSGSSSSKTS SVRNKKGRPP LHKKRVEDES LDNTWLNRTD TMIQTPGPLP APQLTSTVLR 
    ENSRPMGDQI QEPESEHGSE PDFLHNPQMQ ISWLGQPKLE DLNRKDRTGM NYMKVRTGVR 
    HAVRGLMEED AEPIFEDVMM SSRSQLEDMN EEFEDTMVID LPPSRNRRER AELRPDFFDS 
    AAIIEDDSGF GMPMF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.