SMNDC1 | ENSG00000119953 | NCBI 10285

Details for: SMNDC1

Gene ID: 10285

Symbol: SMNDC1

Ensembl ID: ENSG00000119953

Description: survival motor neuron domain containing 1

Associated with

Metabolism of rna
(R-HSA-8953854)
Mrna splicing
(R-HSA-72172)
Mrna splicing - major pathway
(R-HSA-72163)
Processing of capped intron-containing pre-mrna
(R-HSA-72203)
Apoptotic process
(GO:0006915)
Cajal body
(GO:0015030)
Cytoplasm
(GO:0005737)
Mrna processing
(GO:0006397)
Nuclear speck
(GO:0016607)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Rna binding
(GO:0003723)
Rna splicing, via transesterification reactions
(GO:0000375)
Spliceosomal complex
(GO:0005681)

Other Information

Proteins

Survival of motor neuron-related-splicing factor 30

Genular Protein ID: 641075723

Symbol: SPF30_HUMAN

Name: Survival of motor neuron-related-splicing factor 30

UniProtKB Accession Codes:

O75940 B2RA27 D3DRB1 Q5T3K6

Database IDs:

Citations:

PubMed ID: 9731529

Title: Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.

PubMed ID: 9731529

DOI: 10.1038/1700

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9817934

Title: Characterization of a gene encoding survival motor neuron (SMN)-related protein, a constituent of the spliceosome complex.

PubMed ID: 9817934

DOI: 10.1093/hmg/7.13.2149

PubMed ID: 11331595

Title: SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome.

PubMed ID: 11331595

DOI: 10.1093/emboj/20.9.2304

PubMed ID: 11331295

Title: SPF30 is an essential human splicing factor required for assembly of the U4/U5/U6 tri-small nuclear ribonucleoprotein into the spliceosome.

PubMed ID: 11331295

DOI: 10.1074/jbc.m103620200

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 22101937

Title: Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins.

PubMed ID: 22101937

DOI: 10.1038/nsmb.2185

Sequence Information:

Length: 238
Mass: 26711
Checksum: 7F60852AD4D1F53A
Sequence:

MSEDLAKQLA SYKAQLQQVE AALSGNGENE DLLKLKKDLQ EVIELTKDLL STQPSETLAS 
SDSFASTQPT HSWKVGDKCM AVWSEDGQCY EAEIEEIDEE NGTAAITFAG YGNAEVTPLL 
NLKPVEEGRK AKEDSGNKPM SKKEMIAQQR EYKKKKALKK AQRIKELEQE REDQKVKWQQ 
FNNRAYSKNK KGQVKRSIFA SPESVTGKVG VGTCGIADKP MTQYQDTSKY NVRHLMPQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SMNDC1

Associated with

Other Information

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. PubMed ID: 9731529

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and comparative analysis of human chromosome 10. PubMed ID: 15164054

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of a gene encoding survival motor neuron (SMN)-related protein, a constituent of the spliceosome complex. PubMed ID: 9817934

SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome. PubMed ID: 11331595

SPF30 is an essential human splicing factor required for assembly of the U4/U5/U6 tri-small nuclear ribonucleoprotein into the spliceosome. PubMed ID: 11331295

A probability-based approach for high-throughput protein phosphorylation analysis and site localization. PubMed ID: 16964243

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins. PubMed ID: 22101937