Details for: TRAIP

Gene ID: 10293

Symbol: TRAIP

Ensembl ID: ENSG00000183763

Description: TRAF interacting protein

Associated with

Other Information

Genular Protein ID: 1651433543

Symbol: TRAIP_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9104814

Title: TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation.

PubMed ID: 9104814

DOI: 10.1084/jem.185.7.1275

PubMed ID: 19054851

Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.

PubMed ID: 19054851

DOI: 10.1038/nmeth.1273

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14676304

Title: The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor.

PubMed ID: 14676304

DOI: 10.1084/jem.20031187

PubMed ID: 17544371

Title: TRAF-interacting protein (TRIP) is a RING-dependent ubiquitin ligase.

PubMed ID: 17544371

DOI: 10.1016/j.bbrc.2007.05.149

PubMed ID: 22945920

Title: TRAF-interacting protein (TRIP) negatively regulates IFN-beta production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1.

PubMed ID: 22945920

DOI: 10.1084/jem.20120024

PubMed ID: 24553286

Title: TRIP/NOPO E3 ubiquitin ligase promotes ubiquitylation of DNA polymerase eta.

PubMed ID: 24553286

DOI: 10.1242/dev.101196

PubMed ID: 25335891

Title: TRAIP is a regulator of the spindle assembly checkpoint.

PubMed ID: 25335891

DOI: 10.1242/jcs.152579

PubMed ID: 26820530

Title: SUMOylation regulates nuclear localization and stability of TRAIP/RNF206.

PubMed ID: 26820530

DOI: 10.1016/j.bbrc.2016.01.141

PubMed ID: 26781088

Title: TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage.

PubMed ID: 26781088

DOI: 10.1038/ncomms10463

PubMed ID: 27462463

Title: TRAIP regulates replication fork recovery and progression via PCNA.

PubMed ID: 27462463

DOI: 10.1038/celldisc.2016.16

PubMed ID: 26595769

Title: TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism.

PubMed ID: 26595769

DOI: 10.1038/ng.3451

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 30165463

Title: Nucleolar residence of the seckel syndrome protein TRAIP is coupled to ribosomal DNA transcription.

PubMed ID: 30165463

DOI: 10.1093/nar/gky775

PubMed ID: 31545170

Title: TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication.

PubMed ID: 31545170

DOI: 10.7554/elife.48686

PubMed ID: 26711499

Title: TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.

PubMed ID: 26711499

DOI: 10.1083/jcb.201506071

Sequence Information:

  • Length: 469
  • Mass: 53294
  • Checksum: B9EF3808FBC5985B
  • Sequence:
  • MPIRALCTIC SDFFDHSRDV AAIHCGHTFH LQCLIQWFET APSRTCPQCR IQVGKRTIIN 
    KLFFDLAQEE ENVLDAEFLK NELDNVRAQL SQKDKEKRDS QVIIDTLRDT LEERNATVVS 
    LQQALGKAEM LCSTLKKQMK YLEQQQDETK QAQEEARRLR SKMKTMEQIE LLLQSQRPEV 
    EEMIRDMGVG QSAVEQLAVY CVSLKKEYEN LKEARKASGE VADKLRKDLF SSRSKLQTVY 
    SELDQAKLEL KSAQKDLQSA DKEIMSLKKK LTMLQETLNL PPVASETVDR LVLESPAPVE 
    VNLKLRRPSF RDDIDLNATF DVDTPPARPS SSQHGYYEKL CLEKSHSPIQ DVPKKICKGP 
    RKESQLSLGG QSCAGEPDEE LVGAFPIFVR NAILGQKQPK RPRSESSCSK DVVRTGFDGL 
    GGRTKFIQPT DTVMIRPLPV KPKTKVKQRV RVKTVPSLFQ AKLDTFLWS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.