Details for: CCNO

Gene ID: 10309

Symbol: CCNO

Ensembl ID: ENSG00000152669

Description: cyclin O

Associated with

Other Information

Genular Protein ID: 851840577

Symbol: CCNO_HUMAN

Name: N/A

UniProtKB Accession Codes:

P22674 A8K1W5 Q0P6J2 Q9H6B0 Q9UMD5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEMBL 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 2 GO 13 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 1 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2001396

Title: Isolation and characterization of a human cDNA encoding uracil-DNA glycosylase.

PubMed ID: 2001396

DOI: 10.1016/0167-4781(91)90055-q

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8419333

Title: Cell cycle regulation of a human cyclin-like gene encoding uracil-DNA glycosylase.

PubMed ID: 8419333

DOI: 10.1016/s0021-9258(18)54076-x

PubMed ID: 16697536

Title: The cyclin-like uracil DNA glycosylase (UDG) of murine oocytes and its relationship to human and chimpanzee homologues.

PubMed ID: 16697536

DOI: 10.1016/j.gene.2006.02.030

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28860486

Title: A systematic analysis of orphan cyclins reveals CNTD2 as a new oncogenic driver in lung cancer.

PubMed ID: 28860486

DOI: 10.1038/s41598-017-10770-8

PubMed ID: 30087414

Title: The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration.

PubMed ID: 30087414

DOI: 10.1038/s41598-018-30307-x

PubMed ID: 24747639

Title: Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia.

PubMed ID: 24747639

DOI: 10.1038/ng.2961

PubMed ID: 26777464

Title: Systematic analysis of CCNO variants in a defined population: implications for clinical phenotype and differential diagnosis.

PubMed ID: 26777464

DOI: 10.1002/humu.22957

Sequence Information:

  • Length: 350
  • Mass: 38096
  • Checksum: AF1C1D1C34334BED
  • Sequence:
    • MVTPCPTSPS SPAARAGRRD NDQNLRAPVK KSRRPRLRRK QPLHPLNPCP LPGDSGICDL 
FESPSSGSDG AESPSAARGG SPLPGPAQPV AQLDLQTFRD YGQSCYAFRK AQESHFHPRE 
ALARQPQVTA ESRCKLLSWL IPVHRQFGLS FESLCLTVNT LDRFLTTTPV AADCFQLLGV 
TSLLIACKQV EVHPPRVKQL LALCCGAFSR QQLCNLECIV LHKLHFTLGA PTISFFLEHF 
THARVEAGQA EASEALEAQA LARGVAELSL ADYAFTSYSP SLLAICCLAL ADRMLRVSRP 
VDLRLGDHPE AALEDCMGKL QLLVAINSTS LTHMLPVQIC EKCSLPPSSK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.