Details for: RTN3

Gene ID: 10313

Symbol: RTN3

Ensembl ID: ENSG00000133318

Description: reticulon 3

Associated with

Other Information

Genular Protein ID: 1830996175

Symbol: RTN3_HUMAN

Name: Reticulon-3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10331947

Title: Cloning of a novel member of the reticulon gene family (RTN3): gene structure and chromosomal localization to 11q13.

PubMed ID: 10331947

DOI: 10.1006/geno.1999.5807

PubMed ID: 12811824

Title: Pro-apoptotic ASY/Nogo-B protein associates with ASYIP.

PubMed ID: 12811824

DOI: 10.1002/jcp.10297

PubMed ID: 14986927

Title: Overexpression of human reticulon 3 (hRTN3) in astrocytoma.

PubMed ID: 14986927

PubMed ID: 15946766

Title: Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain.

PubMed ID: 15946766

DOI: 10.1016/j.molbrainres.2005.04.020

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12832288

Title: A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family.

PubMed ID: 12832288

DOI: 10.1096/fj.02-1166hyp

PubMed ID: 15286784

Title: Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation.

PubMed ID: 15286784

DOI: 10.1038/nm1088

PubMed ID: 16054885

Title: Reticulon 3 is involved in membrane trafficking between the endoplasmic reticulum and Golgi.

PubMed ID: 16054885

DOI: 10.1016/j.bbrc.2005.07.012

PubMed ID: 15350194

Title: Tissue specificity and regulation of the N-terminal diversity of reticulon 3.

PubMed ID: 15350194

DOI: 10.1042/bj20040458

PubMed ID: 17031492

Title: Adaptor FADD is recruited by RTN3/HAP in ER-bound signaling complexes.

PubMed ID: 17031492

DOI: 10.1007/s10495-006-0082-0

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16965550

Title: Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid beta-protein.

PubMed ID: 16965550

DOI: 10.1111/j.1460-9568.2006.05005.x

PubMed ID: 16979658

Title: Mapping of interaction domains mediating binding between BACE1 and RTN/Nogo proteins.

PubMed ID: 16979658

DOI: 10.1016/j.jmb.2006.07.094

PubMed ID: 17191123

Title: Reticulon 3 mediates Bcl-2 accumulation in mitochondria in response to endoplasmic reticulum stress.

PubMed ID: 17191123

DOI: 10.1007/s10495-006-0574-y

PubMed ID: 17182608

Title: Reticulon 3 binds the 2C protein of enterovirus 71 and is required for viral replication.

PubMed ID: 17182608

DOI: 10.1074/jbc.m611145200

PubMed ID: 17699523

Title: The membrane topology of RTN3 and its effect on binding of RTN3 to BACE1.

PubMed ID: 17699523

DOI: 10.1074/jbc.m704181200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19665976

Title: A class of dynamin-like GTPases involved in the generation of the tubular ER network.

PubMed ID: 19665976

DOI: 10.1016/j.cell.2009.05.025

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21976701

Title: Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation.

PubMed ID: 21976701

DOI: 10.1091/mbc.e11-01-0068

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24262037

Title: Arl6IP1 has the ability to shape the mammalian ER membrane in a reticulon-like fashion.

PubMed ID: 24262037

DOI: 10.1042/bj20131186

PubMed ID: 25612671

Title: Identification and characterization of TMEM33 as a reticulon-binding protein.

PubMed ID: 25612671

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29117567

Title: The host protein reticulon 3.1A is utilized by flaviviruses to facilitate membrane remodelling.

PubMed ID: 29117567

DOI: 10.1016/j.celrep.2017.10.055

PubMed ID: 34313226

Title: RTN3 inhibits RIG-I-mediated antiviral responses by impairing TRIM25-mediated K63-linked polyubiquitination.

PubMed ID: 34313226

DOI: 10.7554/elife.68958

PubMed ID: 32620754

Title: Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes.

PubMed ID: 32620754

DOI: 10.1038/s41467-020-17163-y

Sequence Information:

  • Length: 1032
  • Mass: 112611
  • Checksum: 26B372B82BFC6361
  • Sequence:
  • MAEPSAATQS HSISSSSFGA EPSAPGGGGS PGACPALGTK SCSSSCADSF VSSSSSQPVS 
    LFSTSQEGLS SLCSDEPSSE IMTSSFLSSS EIHNTGLTIL HGEKSHVLGS QPILAKEGKD 
    HLDLLDMKKM EKPQGTSNNV SDSSVSLAAG VHCDRPSIPA SFPEHPAFLS KKIGQVEEQI 
    DKETKNPNGV SSREAKTALD ADDRFTLLTA QKPPTEYSKV EGIYTYSLSP SKVSGDDVIE 
    KDSPESPFEV IIDKAAFDKE FKDSYKESTD DFGSWSVHTD KESSEDISET NDKLFPLRNK 
    EAGRYPMSAL LSRQFSHTNA ALEEVSRCVN DMHNFTNEIL TWDLVPQVKQ QTDKSSDCIT 
    KTTGLDMSEY NSEIPVVNLK TSTHQKTPVC SIDGSTPITK STGDWAEASL QQENAITGKP 
    VPDSLNSTKE FSIKGVQGNM QKQDDTLAEL PGSPPEKCDS LGSGVATVKV VLPDDHLKDE 
    MDWQSSALGE ITEADSSGES DDTVIEDITA DTSFENNKIQ AEKPVSIPSA VVKTGEREIK 
    EIPSCEREEK TSKNFEELVS DSELHQDQPD ILGRSPASEA ACSKVPDTNV SLEDVSEVAP 
    EKPITTENPK LPSTVSPNVF NETEFSLNVT TSAYLESLHG KNVKHIDDSS PEDLIAAFTE 
    TRDKGIVDSE RNAFKAISEK MTDFKTTPPV EVLHENESGG SEIKDIGSKY SEQSKETNGS 
    EPLGVFPTQG TPVASLDLEQ EQLTIKALKE LGERQVEKST SAQRDAELPS EEVLKQTFTF 
    APESWPQRSY DILERNVKNG SDLGISQKPI TIRETTRVDA VSSLSKTELV KKHVLARLLT 
    DFSVHDLIFW RDVKKTGFVF GTTLIMLLSL AAFSVISVVS YLILALLSVT ISFRIYKSVI 
    QAVQKSEEGH PFKAYLDVDI TLSSEAFHNY MNAAMVHINR ALKLIIRLFL VEDLVDSLKL 
    AVFMWLMTYV GAVFNGITLL ILAELLIFSV PIVYEKYKTQ IDHYVGIARD QTKSIVEKIQ 
    AKLPGIAKKK AE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.