Details for: IKZF1

Gene ID: 10320

Symbol: IKZF1

Ensembl ID: ENSG00000185811

Description: IKAROS family zinc finger 1

Associated with

Other Information

Genular Protein ID: 2775180257

Symbol: IKZF1_HUMAN

Name: DNA-binding protein Ikaros

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8964602

Title: Cloning and sequencing of hIk-1, a cDNA encoding a human homologue of mouse Ikaros/LyF-1.

PubMed ID: 8964602

DOI: 10.1016/0165-2478(95)02479-4

PubMed ID: 8543809

Title: The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse.

PubMed ID: 8543809

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10204490

Title: Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes.

PubMed ID: 10204490

DOI: 10.1016/s1074-7613(00)80034-5

PubMed ID: 10753856

Title: The Ikaros gene, a central regulator of lymphoid differentiation, fuses to the BCL6 gene as a result of t(3;7)(q27;p12) translocation in a patient with diffuse large B-cell lymphoma.

PubMed ID: 10753856

PubMed ID: 10978333

Title: Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.

PubMed ID: 10978333

DOI: 10.1074/jbc.m005457200

PubMed ID: 17135265

Title: Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms.

PubMed ID: 17135265

DOI: 10.1074/jbc.m605627200

PubMed ID: 17934067

Title: The role of Ikaros in human erythroid differentiation.

PubMed ID: 17934067

DOI: 10.1182/blood-2007-07-098202

PubMed ID: 19141594

Title: Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing.

PubMed ID: 19141594

DOI: 10.1101/gr.086496.108

PubMed ID: 19129520

Title: Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.

PubMed ID: 19129520

DOI: 10.1056/nejmoa0808253

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22106042

Title: Cell cycle-specific function of Ikaros in human leukemia.

PubMed ID: 22106042

DOI: 10.1002/pbc.23406

PubMed ID: 23071339

Title: Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of Ikaros.

PubMed ID: 23071339

DOI: 10.1073/pnas.1209828109

PubMed ID: 21548011

Title: Congenital pancytopenia and absence of B lymphocytes in a neonate with a mutation in the Ikaros gene.

PubMed ID: 21548011

DOI: 10.1002/pbc.23160

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26981933

Title: Loss of B Cells in Patients with Heterozygous Mutations in IKAROS.

PubMed ID: 26981933

DOI: 10.1056/nejmoa1512234

Sequence Information:

  • Length: 519
  • Mass: 57528
  • Checksum: 7B0129C4E3FE41A8
  • Sequence:
  • MDADEGQDMS QVSGKESPPV SDTPDEGDEP MPIPEDLSTT SGGQQSSKSD RVVASNVKVE 
    TQSDEENGRA CEMNGEECAE DLRMLDASGE KMNGSHRDQG SSALSGVGGI RLPNGKLKCD 
    ICGIICIGPN VLMVHKRSHT GERPFQCNQC GASFTQKGNL LRHIKLHSGE KPFKCHLCNY 
    ACRRRDALTG HLRTHSVGKP HKCGYCGRSY KQRSSLEEHK ERCHNYLESM GLPGTLYPVI 
    KEETNHSEMA EDLCKIGSER SLVLDRLASN VAKRKSSMPQ KFLGDKGLSD TPYDSSASYE 
    KENEMMKSHV MDQAINNAIN YLGAESLRPL VQTPPGGSEV VPVISPMYQL HKPLAEGTPR 
    SNHSAQDSAV ENLLLLSKAK LVPSEREASP SNSCQDSTDT ESNNEEQRSG LIYLTNHIAP 
    HARNGLSLKE EHRAYDLLRA ASENSQDALR VVSTSGEQMK VYKCEHCRVL FLDHVMYTIH 
    MGCHGFRDPF ECNMCGYHSQ DRYEFSSHIT RGEHRFHMS

Genular Protein ID: 1503879454

Symbol: R9R4D9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 268
  • Mass: 30031
  • Checksum: 3A4F6647250035C0
  • Sequence:
  • MDADEGQDMS QVSGKESPPV SDTPDEGDEP MPIPEDLSTT SGGQQSSKSD RVVVTYGADD 
    FRDFHAIIPK SFSRERPFQC NQCGASFTQK GNLLRHIKLH KPLAEGTPRS NHSAQDSAVE 
    NLLLLSKAKL VPSEREASPS NSCQDSTDTE SNNEEQRSGL IYLTNHIAPH ARNGLSLKEE 
    HRAYDLLRAA SENSQDALRV VSTSGEQMKV YKCEHCRVLF LDHVMYTIHM GCHGFRDPFE 
    CNMCGYHSQD RYEFSSHITR GEHRFHMS

Genular Protein ID: 1178375121

Symbol: A0A2R8YFR0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

Sequence Information:

  • Length: 452
  • Mass: 50657
  • Checksum: 7501EAB4CB93681B
  • Sequence:
  • MDADEGQDMS QVSGKESPPV SDTPDEGDEP MPIPEDLSTT SGGQQSSKSD RVVVTYGADD 
    FRDFHAIIPK SFSRERPFQC NQCGASFTQK GNLLRHIKLH SGEKPFKCHL CNYACRRRDA 
    LTGHLRTHSV GKPHKCGYCG RSYKQRSSLE EHKERCHNYL ESMGLPGTLY PVIKEETNHS 
    EMAEDLCKIG SERSLVLDRL ASNVAKRKSS MPQKFLGDKG LSDTPYDSSA SYEKENEMMK 
    SHVMDQAINN AINYLGAESL RPLVQTPPGG SEVVPVISPM YQLHKPLAEG TPRSNHSAQD 
    SAVENLLLLS KAKLVPSERE ASPSNSCQDS TDTESNNEEQ RSGLIYLTNH IAPHARNGLS 
    LKEEHRAYDL LRAASENSQD ALRVVSTSGE QMKVYKCEHC RVLFLDHVMY TIHMGCHGFR 
    DPFECNMCGY HSQDRYEFSS HITRGEHRFH MS

Genular Protein ID: 2111689223

Symbol: A0A8V8TNQ0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

Sequence Information:

  • Length: 539
  • Mass: 59823
  • Checksum: A821F90885A2E8E2
  • Sequence:
  • MDADEGQDMS QVSGKESPPV SDTPDEGDEP MPIPEDLSTT SGGQQSSKSD RVVVTYGADD 
    FRDFHAIIPK SFSPSNVKVE TQSDEENGRA CEMNGEECAE DLRMLDASGE KMNGSHRDQG 
    SSALSGVGGI RLPNGKLKCD ICGIICIGPN VLMVHKRSHT GERPFQCNQC GASFTQKGNL 
    LRHIKLHSGE KPFKCHLCNY ACRRRDALTG HLRTHSVGKP HKCGYCGRSY KQRSSLEEHK 
    ERCHNYLESM GLPGTLYPVI KEETNHSEMA EDLCKIGSER SLVLDRLASN VAKRKSSMPQ 
    KFLGDKGLSD TPYDSSASYE KENEMMKSHV MDQAINNAIN YLGAESLRPL VQTPPGGSEV 
    VPVISPMYQL HKPLAEGTPR SNHSAQDSAV ENLLLLSKAK LVPSEREASP SNSCQDSTDT 
    ESNNEEQRSG LIYLTNHIAP HARNGLSLKE EHRAYDLLRA ASENSQDALR VVSTSGEQMK 
    VYKCEHCRVL FLDHVMYTIH MGCHGFRDPF ECNMCGYHSQ DRYEFSSHIT RGEHRFHMS

Genular Protein ID: 2027240817

Symbol: C9JTB0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

Sequence Information:

  • Length: 174
  • Mass: 19628
  • Checksum: A4F62FEE7226F3D5
  • Sequence:
  • MDADEGQDMS QVSGKESPPV SDTPDEGDEP MPIPEDLSTT SGGQQSSKSD RVVVTYGADD 
    FRDFHAIIPK SFSRKYMPCF WKTKACLHLL SCKYRTCMFL HQPPRYIKYS LFYSLDTYHI 
    IFGYLYHKVQ NEGLGSCAVS WEHGSGVTVR VGVTVALMGL LLRRCCWTAL RLLL

Genular Protein ID: 3215775837

Symbol: A0A2R8Y4D3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

Sequence Information:

  • Length: 77
  • Mass: 8289
  • Checksum: ECF99C94A1A5F05C
  • Sequence:
  • MDADEGQDMS QVSGKESPPV SDTPDEGDEP MPIPEDLSTT SGGQQSSKSD RVVVTYGADD 
    FRDFHAIIPK SFSLLEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.