Details for: IRAG1

Gene ID: 10335

Symbol: IRAG1

Ensembl ID: ENSG00000072952

Description: inositol 1,4,5-triphosphate receptor associated 1

Associated with

Other Information

Genular Protein ID: 3567806852

Symbol: IRAG1_HUMAN

Name: Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate

UniProtKB Accession Codes:

Q9Y6F6 B7Z3T4 B7Z6I2 B7Z9A3 E9PQY6 F5H6A1 J3KQZ7 Q17S00 Q9UNY1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 7 ExpressionAtlas 1 GO 5 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 8 RNAct 1 Reactome 1 RefSeq 6 SAM 1 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10321731

Title: Mrvi1, a common MRV integration site in BXH2 myeloid leukemias, encodes a protein with homology to a lymphoid-restricted membrane protein Jaw1.

PubMed ID: 10321731

DOI: 10.1038/sj.onc.1202419

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14729908

Title: InsP3R-associated cGMP kinase substrate (IRAG) is essential for nitric oxide-induced inhibition of calcium signaling in human colonic smooth muscle.

PubMed ID: 14729908

DOI: 10.1074/jbc.m313365200

PubMed ID: 16990611

Title: IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation.

PubMed ID: 16990611

DOI: 10.1182/blood-2005-10-026294

PubMed ID: 17312387

Title: Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells.

PubMed ID: 17312387

DOI: 10.4161/cbt.6.3.3704

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 904
  • Mass: 97957
  • Checksum: 94891F4B4807A61A
  • Sequence:
    • MGMDLTCPFG ISPACGAQAS WSIFGADAAE VPGTRGHSQQ EAAMPHIPED EEPPGEPQAA 
QSPAGQGPPA AGVSCSPTPT IVLTGDATSP EGETDKNLAN RVHSPHKRLS HRHLKVSTAS 
LTSVDPAGHI IDLVNDQLPD ISISEEDKKK NLALLEEAKL VSERFLTRRG RKSRSSPGDS 
PSAVSPNLSP SASPTSSRSN SLTVPTPPGL DVCSGPPSPL PGAPPQQKGD EADVSSPHPG 
EPNVPKGLAD RKQNDQRKVS QGRLAPRPPP VEKSKEIAIE QKENFDPLQY PETTPKGLAP 
VTNSSGKMAL NSPQPGPVES ELGKQLLKTG WEGSPLPRSP TQDAAGVGPP ASQGRGPAGE 
PMGPEAGSKA ELPPTVSRPP LLRGLSWDSG PEEPGPRLQK VLAKLPLAEE EKRFAGKAGG 
KLAKAPGLKD FQIQVQPVRM QKLTKLREEH ILMRNQNLVG LKLPDLSEAA EQEKGLPSEL 
SPAIEEEESK SGLDVMPNIS DVLLRKLRVH RSLPGSAPPL TEKEVENVFV QLSLAFRNDS 
YTLESRINQA ERERNLTEEN TEKELENFKA SITSSASLWH HCEHRETYQK LLEDIAVLHR 
LAARLSSRAE VVGAVRQEKR MSKATEVMMQ YVENLKRTYE KDHAELMEFK KLANQNSSRS 
CGPSEDGVPR TARSMSLTLG KNMPRRRVSV AVVPKFNALN LPGQTPSSSS IPSLPALSES 
PNGKGSLPVT SALPALLENG KTNGDPDCEA SAPALTLSCL EELSQETKAR MEEEAYSKGF 
QEGLKKTKEL QDLKEEEEEQ KSESPEEPEE VEETEEEEKG PRSSKLEELV HFLQVMYPKL 
CQHWQVIWMM AAVMLVLTVV LGLYNSYNSC AEQADGPLGR STCSAAQRDS WWSSGLQHEQ 
PTEQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.