Details for: ABCA8

Gene ID: 10351

Symbol: ABCA8

Ensembl ID: ENSG00000141338

Description: ATP binding cassette subfamily A member 8

Associated with

Other Information

Genular Protein ID: 2266892423

Symbol: ABCA8_HUMAN

Name: ABC-type organic anion transporter ABCA8

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10048485

Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10048485

DOI: 10.1093/dnares/5.6.355

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12379217

Title: Functional analysis of ABCA8, a new drug transporter.

PubMed ID: 12379217

DOI: 10.1016/s0006-291x(02)02389-6

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 23560799

Title: ABCA8 stimulates sphingomyelin production in oligodendrocytes.

PubMed ID: 23560799

DOI: 10.1042/bj20121764

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29300488

Title: ATP-Binding Cassette Transporter A Subfamily 8 Is a Sinusoidal Efflux Transporter for Cholesterol and Taurocholate in Mouse and Human Liver.

PubMed ID: 29300488

DOI: 10.1021/acs.molpharmaceut.7b00679

PubMed ID: 12111378

Title: Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.

PubMed ID: 12111378

DOI: 10.1007/s100380200041

PubMed ID: 28882873

Title: ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels.

PubMed ID: 28882873

DOI: 10.1161/atvbaha.117.309574

Sequence Information:

  • Length: 1621
  • Mass: 183677
  • Checksum: C50C8E2624BA4734
  • Sequence:
  • MRKRKISVCQ QTWALLCKNF LKKWRMKRES LMEWLNSLLL LLCLYIYPHS HQVNDFSSLL 
    TMDLGRVDTF NESRFSVVYT PVTNTTQQIM NKVASTPFLA GKEVLGLPDE ESIKEFTANY 
    PEEIVRVTFT NTYSYHLKFL LGHGMPAKKE HKDHTAHCYE TNEDVYCEVS VFWKEGFVAL 
    QAAINAAIIE ITTNHSVMEE LMSVTGKNMK MHSFIGQSGV ITDLYLFSCI ISFSSFIYYA 
    SVNVTRERKR MKALMTMMGL RDSAFWLSWG LLYAGFIFIM ALFLALVIRS TQFIILSGFM 
    VVFSLFLLYG LSLVALAFLM SILVKKSFLT GLVVFLLTVF WGCLGFTSLY RHLPASLEWI 
    LSLLSPFAFM LGMAQLLHLD YDLNSNAFPH PSDGSNLIVA TNFMLAFDTC LYLALAIYFE 
    KILPNEYGHR RPPLFFLKSS FWSQTQKTDH VALEDEMDAD PSFHDSFEQA PPEFQGKEAI 
    RIRNVTKEYK GKPDKIEALK DLVFDIYEGQ ITAILGHSGA GKSTLLNILS GLSVPTKGSV 
    TIYNNKLSEM ADLENLSKLT GVCPQSNVQF DFLTVRENLR LFAKIKGILP QEVDKEIQRV 
    LLELEMKNIQ DVLAQNLSGG QKRKLTFGIA ILGDPQIFLL DEPTAGLDPF SRHQVWNLLK 
    ERKTDRVILF STQFMDEADI LADRKVFLSQ GKLKCAGSSL FLKKKWGIGY HLSLQLNEIC 
    VEENITSLVK QHIPDAKLSA KSEGKLIYTL PLERTNKFPE LYKDLDSYPD LGIENYGVSM 
    TTLNEVFLKL EGKSTINESD IAILGEVQAE KADDTERLVE MEQVLSSLNK MRKTIGGVAL 
    WRQQICAIAR VRLLKLKHER KALLALLLIL MAGFCPLLVE YTMVKIYQNS YTWELSPHLY 
    FLAPGQQPHD PLTQLLIINK TGASIDDFIQ SVEHQNIALE VDAFGTRNGT DDPSYNGAIT 
    VCCNEKNYSF SLACNAKRLN CFPVLMDIVS NGLLGMVKPS VHIRTERSTF LENGQDNPIG 
    FLAYIMFWLV LTSSCPPYIA MSSIDDYKNR ARSQLRISGL SPSAYWFGQA LVDVSLYFLV 
    FVFIYLMSYI SNFEDMLLTI IHIIQIPCAV GYSFSLIFMT YVISFIFRKG RKNSGIWSFC 
    FYVVTVFSVA GFAFSIFESD IPFIFTFLIP PATMIGCLFL SSHLLFSSLF SEERMDVQPF 
    LVFLIPFLHF IIFLFTLRCL EWKFGKKSMR KDPFFRISPR SSDVCQNPEE PEGEDEDVQM 
    ERVRTANALN STNFDEKPVI IASCLRKEYA GKRKGCFSKR KNKIATRNVS FCVRKGEVLG 
    LLGHNGAGKS TSIKVITGDT KPTAGQVLLK GSGGGDALEF LGYCPQENAL WPNLTVRQHL 
    EVYAAVKGLR KGDAEVAITR LVDALKLQDQ LKSPVKTLSE GIKRKLCFVL SILGNPSVVL 
    LDEPSTGMDP EGQQQMWQAI RATFRNTERG ALLTTHYMAE AEAVCDRVAI MVSGRLRCIG 
    SIQHLKSKFG KDYLLEMKVK NLAQVEPLHA EILRLFPQAA RQERYSSLMV YKLPVEDVQP 
    LAQAFFKLEK VKQSFDLEEY SLSQSTLEQV FLELSKEQEL GDFEEDFDPS VKWKLLPQEE 
    P

Genular Protein ID: 124558623

Symbol: A0A0A0MSU4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1616
  • Mass: 183067
  • Checksum: 2E3313D2B65254A6
  • Sequence:
  • MRKRKISVCQ QTWALLCKNF LKKWRMKRES LMEWLNSLLL LLCLYIYPHS HQVNDFSSLL 
    TMDLGRVDTF NESRFSVVYT PVTNTTQQIM NKVASTPFLA GKEVLGLPDE ESIKEFTANY 
    PEEIVRVTFT NTYSYHLKFL LGHGMPAKKE HKDHTAHCYE TNEDVYCEVS VFWKEGFVAL 
    QAAINAAIIE ITTNHSVMEE LMSVTGKNMK MHSFIGQSGV ITDLYLFSCI ISFSSFIYYA 
    SVNVTRERKR MKALMTMMGL RDSAFWLSWG LLYAGFIFIM ALFLALVIRS TQFIILSGFM 
    VVFSLFLLYG LSLVALAFLM SILVKKSFLT GLVVFLLTVF WGCLGFTSLY RHLPASLEWI 
    LSLLSPFAFM LGMAQLLHLD YDLNSNAFPH PSDGSNLIVA TNFMLAFDTC LYLALAIYFE 
    KILPNEYGHR RPPLFFLKSS FWSQTQKTDH VALEDEMDAD PSFHDSFEQA PPEFQGKEAI 
    RIRNVTKEYK GKPDKIEALK DLVFDIYEGQ ITAILGHSGA GKSTLLNILS GLSVPTKGSV 
    TIYNNKLSEM ADLENLSKLT GVCPQSNVQF DFLTVRENLR LFAKIKGILP QEVDKEIQRV 
    LLELEMKNIQ DVLAQNLSGG QKRKLTFGIA ILGDPQIFLL DEPTAGLDPF SRHQVWNLLK 
    ERKTDRVILF STQFMDEADI LADRKVFLSQ GKLKCAGSSL FLKKKWGIGY HLSLQLNEIC 
    VEENITSLVK QHIPDAKLSA KSEGKLIYTL PLERTNKFPE LYKDLDSYPD LGIENYGVSM 
    TTLNEVFLKL EGKSTINESD IAILGEVQAE KADDTERLVE MEQVLSSLNK MRKTIGGVAL 
    WRQQICAIAR VRLLKLKHER KALLALLLIL MAGFCPLLVE YTMVKIYQNS YTWELSPHLY 
    FLAPGQQPHD PLTQLLIINK TGASIDDFIQ SVEHQNIALE VDAFGTRNGT DDPSYNGAIT 
    VCCNEKNYSF SLACNAKRLN CFPVLMDIVS NGLLGMVKPS VHIRTERSTF LENGQDNPIG 
    FLAYIMFWLV LTSSCPPYIA MSSIDDYKNR ARSQLRISGL SPSAYWFGQA LVDVSLYFLV 
    FVFIYLMSYI SNFEDMLLTI IHIIQIPCAV GYSFSLIFMT YVISFIFRKG RKNSGIWSFC 
    FYVVTVFSVA GFAFSIFESD IPFIFTFLIP PATMIGCLFL SSHLLFSSLF SEERMDVQPF 
    LVFLIPFLHF IIFLFTLRCL EWKFGKKSMR KDPFFSSDVC QNPEEPEGED EDVQMERVRT 
    ANALNSTNFD EKPVIIASCL RKEYAGKRKG CFSKRKNKIA TRNVSFCVRK GEVLGLLGHN 
    GAGKSTSIKV ITGDTKPTAG QVLLKGSGGG DALEFLGYCP QENALWPNLT VRQHLEVYAA 
    VKGLRKGDAE VAITRLVDAL KLQDQLKSPV KTLSEGIKRK LCFVLSILGN PSVVLLDEPS 
    TGMDPEGQQQ MWQAIRATFR NTERGALLTT HYMAEAEAVC DRVAIMVSGR LRCIGSIQHL 
    KSKFGKDYLL EMKVKNLAQV EPLHAEILRL FPQAARQERY SSLMVYKLPV EDVQPLAQAF 
    FKLEKVKQSF DLEEYSLSQS TLEQVFLELS KEQELGDFEE DFDPSVKWKL LPQEEP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.