Gene TUBA1B - ENSG00000123416 | NCBI Gene ID: 10376

Details for: TUBA1B

Gene ID: 10376

Symbol: TUBA1B

Ensembl ID: ENSG00000123416

Description: tubulin alpha 1b

Associated with

Activation of ampk downstream of nmdars
(R-HSA-9619483)
Activation of nmda receptors and postsynaptic events
(R-HSA-442755)
Adaptive immune system
(R-HSA-1280218)
Aggrephagy
(R-HSA-9646399)
Antiviral mechanism by ifn-stimulated genes
(R-HSA-1169410)
Asparagine n-linked glycosylation
(R-HSA-446203)
Assembly and cell surface presentation of nmda receptors
(R-HSA-9609736)
Autophagy
(R-HSA-9612973)
Axon guidance
(R-HSA-422475)
Carboxyterminal post-translational modifications of tubulin
(R-HSA-8955332)
Cell cycle
(R-HSA-1640170)
Cell cycle, mitotic
(R-HSA-69278)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Chaperonin-mediated protein folding
(R-HSA-390466)
Cilium assembly
(R-HSA-5617833)
Cooperation of prefoldin and tric/cct in actin and tubulin folding
(R-HSA-389958)
Copi-dependent golgi-to-er retrograde traffic
(R-HSA-6811434)
Copi-independent golgi-to-er retrograde traffic
(R-HSA-6811436)
Copi-mediated anterograde transport
(R-HSA-6807878)
Cytokine signaling in immune system
(R-HSA-1280215)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Eml4 and nudc in mitotic spindle formation
(R-HSA-9648025)
Er to golgi anterograde transport
(R-HSA-199977)
Factors involved in megakaryocyte development and platelet production
(R-HSA-983231)
Formation of tubulin folding intermediates by cct/tric
(R-HSA-389960)
G2/m transition
(R-HSA-69275)
Gap junction assembly
(R-HSA-190861)
Gap junction trafficking
(R-HSA-190828)
Gap junction trafficking and regulation
(R-HSA-157858)
Golgi-to-er retrograde transport
(R-HSA-8856688)
Hcmv early events
(R-HSA-9609690)
Hcmv infection
(R-HSA-9609646)
Hedgehog 'off' state
(R-HSA-5610787)
Hemostasis
(R-HSA-109582)
Hsp90 chaperone cycle for steroid hormone receptors (shr) in the presence of ligand
(R-HSA-3371497)
Immune system
(R-HSA-168256)
Infectious disease
(R-HSA-5663205)
Interferon signaling
(R-HSA-913531)
Intra-golgi and retrograde golgi-to-er traffic
(R-HSA-6811442)
Intraflagellar transport
(R-HSA-5620924)
Kinesins
(R-HSA-983189)
L1cam interactions
(R-HSA-373760)
Macroautophagy
(R-HSA-1632852)
Membrane trafficking
(R-HSA-199991)
Metabolism of proteins
(R-HSA-392499)
Mhc class ii antigen presentation
(R-HSA-2132295)
Microtubule-dependent trafficking of connexons from golgi to the plasma membrane
(R-HSA-190840)
Mitotic anaphase
(R-HSA-68882)
Mitotic g2-g2/m phases
(R-HSA-453274)
Mitotic metaphase and anaphase
(R-HSA-2555396)
Mitotic prometaphase
(R-HSA-68877)
M phase
(R-HSA-68886)
Nervous system development
(R-HSA-9675108)
Neuronal system
(R-HSA-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-HSA-112314)
Nuclear envelope (ne) reassembly
(R-HSA-2995410)
Organelle biogenesis and maintenance
(R-HSA-1852241)
Pkr-mediated signaling
(R-HSA-9833482)
Post-chaperonin tubulin folding pathway
(R-HSA-389977)
Post-translational protein modification
(R-HSA-597592)
Post nmda receptor activation events
(R-HSA-438064)
Protein folding
(R-HSA-391251)
Recruitment of numa to mitotic centrosomes
(R-HSA-380320)
Recycling pathway of l1
(R-HSA-437239)
Resolution of sister chromatid cohesion
(R-HSA-2500257)
Rho gtpase cycle
(R-HSA-9012999)
Rho gtpase effectors
(R-HSA-195258)
Rho gtpases activate formins
(R-HSA-5663220)
Rho gtpases activate iqgaps
(R-HSA-5626467)
Rhoh gtpase cycle
(R-HSA-9013407)
Sealing of the nuclear envelope (ne) by escrt-iii
(R-HSA-9668328)
Selective autophagy
(R-HSA-9663891)
Separation of sister chromatids
(R-HSA-2467813)
Signaling by hedgehog
(R-HSA-5358351)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
The role of gtse1 in g2/m progression after g2 checkpoint
(R-HSA-8852276)
Translocation of slc2a4 (glut4) to the plasma membrane
(R-HSA-1445148)
Transmission across chemical synapses
(R-HSA-112315)
Transport of connexons to the plasma membrane
(R-HSA-190872)
Transport to the golgi and subsequent modification
(R-HSA-948021)
Vesicle-mediated transport
(R-HSA-5653656)
Viral infection pathways
(R-HSA-9824446)
Cytoskeleton-dependent intracellular transport
(GO:0030705)
Double-stranded rna binding
(GO:0003725)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Microtubule-based process
(GO:0007017)
Microtubule cytoskeleton organization
(GO:0000226)
Mitotic cell cycle
(GO:0000278)
Protein binding
(GO:0005515)
Structural constituent of cytoskeleton
(GO:0005200)
Structural molecule activity
(GO:0005198)
Ubiquitin protein ligase binding
(GO:0031625)

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: early promyelocyte (CL0002154)
Fold Change: 5.19
Marker Score: 4155
Cell Name: cord blood hematopoietic stem cell (CL2000095)
Fold Change: 4.75
Marker Score: 3582
Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 4.23
Marker Score: 6517
Cell Name: chromaffin cell (CL0000166)
Fold Change: 4.17
Marker Score: 5867
Cell Name: radial glial cell (CL0000681)
Fold Change: 4.15
Marker Score: 1529
Cell Name: pancreatic A cell (CL0000171)
Fold Change: 4
Marker Score: 3912
Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 3.99
Marker Score: 10138
Cell Name: GABAergic neuron (CL0000617)
Fold Change: 3.88
Marker Score: 16185
Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 3.76
Marker Score: 5439
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 3.68
Marker Score: 125268
Cell Name: glycinergic neuron (CL1001509)
Fold Change: 3.53
Marker Score: 4268
Cell Name: neural progenitor cell (CL0011020)
Fold Change: 3.44
Marker Score: 13324.5
Cell Name: embryonic stem cell (CL0002322)
Fold Change: 3.42
Marker Score: 1095
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.41
Marker Score: 8327
Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 3.34
Marker Score: 3152
Cell Name: retinal rod cell (CL0000604)
Fold Change: 3.33
Marker Score: 9499
Cell Name: mesodermal cell (CL0000222)
Fold Change: 3.33
Marker Score: 43887
Cell Name: Sertoli cell (CL0000216)
Fold Change: 3.24
Marker Score: 19231
Cell Name: late promyelocyte (CL0002151)
Fold Change: 3.23
Marker Score: 811
Cell Name: mature T cell (CL0002419)
Fold Change: 3.14
Marker Score: 31123
Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 3.12
Marker Score: 5277
Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 3.09
Marker Score: 2638
Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 3.09
Marker Score: 20080
Cell Name: lung macrophage (CL1001603)
Fold Change: 3.06
Marker Score: 3506
Cell Name: erythroblast (CL0000765)
Fold Change: 3.05
Marker Score: 1905
Cell Name: fibroblast of breast (CL4006000)
Fold Change: 3.04
Marker Score: 1736
Cell Name: chondrocyte (CL0000138)
Fold Change: 3.02
Marker Score: 1358
Cell Name: endocardial cell (CL0002350)
Fold Change: 3
Marker Score: 1696
Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: 3
Marker Score: 987
Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 3
Marker Score: 6088
Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 2.97
Marker Score: 3200
Cell Name: basophil (CL0000767)
Fold Change: 2.96
Marker Score: 1408
Cell Name: myelocyte (CL0002193)
Fold Change: 2.96
Marker Score: 1279
Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.95
Marker Score: 705
Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
Fold Change: 2.93
Marker Score: 1332
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.92
Marker Score: 11256
Cell Name: granulocyte (CL0000094)
Fold Change: 2.92
Marker Score: 1307
Cell Name: endothelial cell (CL0000115)
Fold Change: 2.9
Marker Score: 2597
Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 2.89
Marker Score: 1205
Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 2.88
Marker Score: 3077
Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 2.87
Marker Score: 2702
Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: 2.86
Marker Score: 2177.5
Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 2.83
Marker Score: 1777
Cell Name: epithelial cell (CL0000066)
Fold Change: 2.79
Marker Score: 4444
Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 2.78
Marker Score: 13673
Cell Name: blood cell (CL0000081)
Fold Change: 2.78
Marker Score: 32289.5
Cell Name: Unknown (CL0000548)
Fold Change: 2.77
Marker Score: 2017
Cell Name: stromal cell (CL0000499)
Fold Change: 2.76
Marker Score: 3238
Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 2.76
Marker Score: 7627
Cell Name: Kupffer cell (CL0000091)
Fold Change: 2.75
Marker Score: 2755
Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 2.74
Marker Score: 2306
Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
Fold Change: 2.74
Marker Score: 7095
Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 2.74
Marker Score: 815
Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 2.73
Marker Score: 5446
Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 2.72
Marker Score: 3738
Cell Name: muscle precursor cell (CL0000680)
Fold Change: 2.72
Marker Score: 704
Cell Name: pro-T cell (CL0000827)
Fold Change: 2.72
Marker Score: 11116
Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.71
Marker Score: 27448
Cell Name: smooth muscle cell (CL0000192)
Fold Change: 2.71
Marker Score: 1782
Cell Name: reticular cell (CL0000432)
Fold Change: 2.7
Marker Score: 987
Cell Name: motor neuron (CL0000100)
Fold Change: 2.67
Marker Score: 1586
Cell Name: pancreatic D cell (CL0000173)
Fold Change: 2.64
Marker Score: 1148
Cell Name: inhibitory motor neuron (CL0008015)
Fold Change: 2.64
Marker Score: 1246
Cell Name: neural crest cell (CL0011012)
Fold Change: 2.64
Marker Score: 2817
Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 2.63
Marker Score: 5499
Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 2.62
Marker Score: 882
Cell Name: type I NK T cell (CL0000921)
Fold Change: 2.62
Marker Score: 2056.5
Cell Name: alveolar macrophage (CL0000583)
Fold Change: 2.61
Marker Score: 66922
Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 2.61
Marker Score: 2836
Cell Name: naive B cell (CL0000788)
Fold Change: 2.61
Marker Score: 2327
Cell Name: pericyte (CL0000669)
Fold Change: 2.6
Marker Score: 1520
Cell Name: alternatively activated macrophage (CL0000890)
Fold Change: 2.59
Marker Score: 1081
Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 2.59
Marker Score: 682.5
Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 2.59
Marker Score: 2909
Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 2.58
Marker Score: 6071
Cell Name: decidual cell (CL2000002)
Fold Change: 2.57
Marker Score: 11063
Cell Name: endothelial tip cell (CL0000704)
Fold Change: 2.56
Marker Score: 597
Cell Name: granulosa cell (CL0000501)
Fold Change: 2.56
Marker Score: 25751.5
Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 2.55
Marker Score: 991
Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: 2.54
Marker Score: 1242
Cell Name: microglial cell (CL0000129)
Fold Change: 2.54
Marker Score: 4632
Cell Name: mammary gland epithelial cell (CL0002327)
Fold Change: 2.54
Marker Score: 903
Cell Name: lung ciliated cell (CL1000271)
Fold Change: 2.54
Marker Score: 1203
Cell Name: supporting cell (CL0000630)
Fold Change: 2.53
Marker Score: 4761
Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 2.53
Marker Score: 2178
Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 2.53
Marker Score: 3580
Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 2.52
Marker Score: 1054
Cell Name: interstitial cell of Cajal (CL0002088)
Fold Change: 2.52
Marker Score: 871
Cell Name: promonocyte (CL0000559)
Fold Change: 2.52
Marker Score: 1620.5
Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 2.51
Marker Score: 1152
Cell Name: pneumocyte (CL0000322)
Fold Change: 2.51
Marker Score: 4030
Cell Name: theca cell (CL0000503)
Fold Change: 2.5
Marker Score: 1793
Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 2.49
Marker Score: 10383
Cell Name: starburst amacrine cell (CL0004232)
Fold Change: 2.49
Marker Score: 706
Cell Name: IgA plasmablast (CL0000984)
Fold Change: 2.49
Marker Score: 653
Cell Name: mature microglial cell (CL0002629)
Fold Change: 2.48
Marker Score: 895
Cell Name: fibroblast of lung (CL0002553)
Fold Change: 2.47
Marker Score: 6477
Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 2.47
Marker Score: 6730
Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
Fold Change: 2.47
Marker Score: 1912
Cell Name: meningeal macrophage (CL0000879)
Fold Change: 2.47
Marker Score: 695

Hover over a box to see details here...

**Key characteristics:** - It is a microtubule-associated protein (MAP). - It is expressed in a variety of cell types, including early promyelocytes, cord blood hematopoietic stem cells, and fibroblasts. - It is a highly dynamic protein that undergoes significant changes in its structure and function depending on the cellular context. **Pathways and functions:** - **Adaptive immune system:** TUBA1B is a key component of microvilli in epithelial cells, where it is involved in the formation of cell-cell junctions and the maintenance of epithelial integrity. - **Autophagy:** It is a key regulator of autophagy, a cellular process that removes damaged or unnecessary proteins and organelles from the cell. - **Cell cycle:** TUBA1B is involved in the regulation of cell cycle progression by interacting with other microtubule proteins. - **Cellular responses to stimuli:** It plays a role in the regulation of cellular responses to various stimuli, including growth factors, cytokines, and stress factors. - **Cytokine signaling in immune system:** TUBA1B is a key component of the cytokine signaling pathway in immune cells, where it interacts with various cytokine receptors. - **Developmental biology:** It is expressed in the developing embryo and plays a role in the specification of neural cell fate. - **Disease:** Mutations in TUBA1B have been linked to several human diseases, including cancer, neurodegenerative disorders, and developmental abnormalities. - **Hemostasis:** It is involved in blood clotting and hemostasis by interacting with clotting factors and promoting the formation of blood clots. - **Immune system:** It is expressed on immune cells and plays a role in the regulation of immune responses. - **Macroautophagy:** It is involved in macroautophagy, a process that removes damaged or dysfunctional organelles from the cell. - **Membrane trafficking:** It is involved in the transport of proteins and organelles between different cellular compartments. - **Protein folding:** It helps to maintain the proper folding and stability of other microtubule proteins. - **Signaling by hedgehog:** It is a key component of the hedgehog signaling pathway, which is involved in cell growth, differentiation, and migration. - **Signal transduction:** It is a key component of various signal transduction pathways in cells. - **Transmission across chemical synapses:** It is involved in the transmission of chemical signals between neurons. - **Vesicle-mediated transport:** It is involved in the transport of vesicles between different cellular compartments. **Clinical significance:** - Mutations in TUBA1B have been linked to several human diseases, including cancer, neurodegenerative disorders, and developmental abnormalities. - Targeting TUBA1B has been investigated as a potential therapeutic strategy for these diseases. - TUBA1B is a promising target for the development of novel therapies for cancer and neurodegenerative disorders.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Tubulin alpha-1B chain

Genular Protein ID: 2199757415

Symbol: TBA1B_HUMAN

Name: Tubulin alpha-1B chain

UniProtKB Accession Codes:

P68363 P04687 P05209 Q27I68 Q8WU19

Database IDs:

Citations:

PubMed ID: 6646120

Title: Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions.

PubMed ID: 6646120

DOI: 10.1128/mcb.3.10.1738-1745.1983

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8619814

Title: C-terminal fragments of alpha- and beta-tubulin form amyloid fibrils in vitro and associate with amyloid deposits of familial cerebral amyloid angiopathy, British type.

PubMed ID: 8619814

DOI: 10.1006/bbrc.1996.0211

PubMed ID: 10339593

Title: Microtubule dysfunction by posttranslational nitrotyrosination of alpha-tubulin: a nitric oxide-dependent mechanism of cellular injury.

PubMed ID: 10339593

DOI: 10.1073/pnas.96.11.6365

PubMed ID: 19524510

Title: Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation.

PubMed ID: 19524510

DOI: 10.1016/j.cell.2009.05.020

PubMed ID: 24906155

Title: Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.

PubMed ID: 24906155

DOI: 10.1016/j.cell.2014.03.061

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 25908662

Title: Mitosis. Microtubule detyrosination guides chromosomes during mitosis.

PubMed ID: 25908662

DOI: 10.1126/science.aaa5175

PubMed ID: 26875866

Title: Graded control of microtubule severing by tubulin glutamylation.

PubMed ID: 26875866

DOI: 10.1016/j.cell.2016.01.019

PubMed ID: 27518565

Title: Dual chromatin and cytoskeletal remodeling by SETD2.

PubMed ID: 27518565

DOI: 10.1016/j.cell.2016.07.005

PubMed ID: 26972003

Title: Alpha-tubulin tyrosination and CLIP-170 phosphorylation regulate the initiation of dynein-driven transport in neurons.

PubMed ID: 26972003

DOI: 10.1016/j.celrep.2016.02.046

PubMed ID: 29146869

Title: Vasohibins encode tubulin detyrosinating activity.

PubMed ID: 29146869

DOI: 10.1126/science.aao5676

PubMed ID: 32747782

Title: Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.

PubMed ID: 32747782

DOI: 10.1038/s41594-020-0462-0

PubMed ID: 31727855

Title: TTC5 mediates autoregulation of tubulin via mRNA degradation.

PubMed ID: 31727855

DOI: 10.1126/science.aaz4352

PubMed ID: 17563362

Title: Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition.

PubMed ID: 17563362

DOI: 10.1073/pnas.0703876104

PubMed ID: 34996871

Title: Structural transitions in the GTP cap visualized by cryo-electron microscopy of catalytically inactive microtubules.

PubMed ID: 34996871

DOI: 10.1073/pnas.2114994119

PubMed ID: 35482892

Title: Posttranslational modification of microtubules by the MATCAP detyrosinase.

PubMed ID: 35482892

DOI: 10.1126/science.abn6020

Sequence Information:

Length: 451
Mass: 50152
Checksum: 94355B4EC2086429
Sequence:

MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK 
HVPRAVFVDL EPTVIDEVRT GTYRQLFHPE QLITGKEDAA NNYARGHYTI GKEIIDLVLD 
RIRKLADQCT GLQGFLVFHS FGGGTGSGFT SLLMERLSVD YGKKSKLEFS IYPAPQVSTA 
VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL ISQIVSSITA 
SLRFDGALNV DLTEFQTNLV PYPRIHFPLA TYAPVISAEK AYHEQLSVAE ITNACFEPAN 
QMVKCDPRHG KYMACCLLYR GDVVPKDVNA AIATIKTKRS IQFVDWCPTG FKVGINYQPP 
TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LDHKFDLMYA KRAFVHWYVG EGMEEGEFSE 
AREDMAALEK DYEEVGVDSV EGEGEEEGEE Y

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.

Details for: TUBA1B

Associated with

Cells (max top 100)

Other Information

Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions. PubMed ID: 6646120

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

C-terminal fragments of alpha- and beta-tubulin form amyloid fibrils in vitro and associate with amyloid deposits of familial cerebral amyloid angiopathy, British type. PubMed ID: 8619814

Microtubule dysfunction by posttranslational nitrotyrosination of alpha-tubulin: a nitric oxide-dependent mechanism of cellular injury. PubMed ID: 10339593

Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation. PubMed ID: 19524510

Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase. PubMed ID: 24906155

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Mitosis. Microtubule detyrosination guides chromosomes during mitosis. PubMed ID: 25908662

Graded control of microtubule severing by tubulin glutamylation. PubMed ID: 26875866

Dual chromatin and cytoskeletal remodeling by SETD2. PubMed ID: 27518565

Alpha-tubulin tyrosination and CLIP-170 phosphorylation regulate the initiation of dynein-driven transport in neurons. PubMed ID: 26972003

Vasohibins encode tubulin detyrosinating activity. PubMed ID: 29146869

Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes. PubMed ID: 32747782

TTC5 mediates autoregulation of tubulin via mRNA degradation. PubMed ID: 31727855

Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition. PubMed ID: 17563362

Structural transitions in the GTP cap visualized by cryo-electron microscopy of catalytically inactive microtubules. PubMed ID: 34996871

Posttranslational modification of microtubules by the MATCAP detyrosinase. PubMed ID: 35482892