IRF9 | ENSG00000213928 | NCBI 10379

Details for: IRF9

Gene ID: 10379

Symbol: IRF9

Ensembl ID: ENSG00000213928

Description: interferon regulatory factor 9

Associated with

Cytokine signaling in immune system
(R-HSA-1280215)
Immune system
(R-HSA-168256)
Interferon alpha/beta signaling
(R-HSA-909733)
Interferon gamma signaling
(R-HSA-877300)
Interferon signaling
(R-HSA-913531)
Cell surface receptor signaling pathway
(GO:0007166)
Chromatin
(GO:0000785)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Defense response to virus
(GO:0051607)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Immune system process
(GO:0002376)
Isgf3 complex
(GO:0070721)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific double-stranded dna binding
(GO:1990837)
Transcription by rna polymerase ii
(GO:0006366)

Other Information

Proteins

Interferon regulatory factor 9

Genular Protein ID: 856920352

Symbol: IRF9_HUMAN

Name: Interferon regulatory factor 9

UniProtKB Accession Codes:

Q00978 D3DS61

Database IDs:

Citations:

PubMed ID: 1630447

Title: Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins.

PubMed ID: 1630447

DOI: 10.1128/mcb.12.8.3315-3324.1992

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11846981

Title: Nuclear/cytoplasmic localization of IRFs in response to viral infection or interferon stimulation.

PubMed ID: 11846981

DOI: 10.1089/107999002753452719

PubMed ID: 10702714

Title: Viral inhibition of interferon signal transduction.

PubMed ID: 10702714

DOI: 10.1159/000053968

PubMed ID: 30143481

Title: Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency.

PubMed ID: 30143481

DOI: 10.1084/jem.20180628

PubMed ID: 30826365

Title: Impaired control of multiple viral infections in a family with complete IRF9 deficiency.

PubMed ID: 30826365

DOI: 10.1016/j.jaci.2019.02.019

PubMed ID: 32699158

Title: Herpes Simplex Virus Type 2 Inhibits Type I IFN Signaling Mediated by the Novel E3 Ubiquitin Protein Ligase Activity of Viral Protein ICP22.

PubMed ID: 32699158

DOI: 10.4049/jimmunol.2000418

Sequence Information:

Length: 393
Mass: 43696
Checksum: F8E3784354BFD4A9
Sequence:

MASGRARCTR KLRNWVVEQV ESGQFPGVCW DDTAKTMFRI PWKHAGKQDF REDQDAAFFK 
AWAIFKGKYK EGDTGGPAVW KTRLRCALNK SSEFKEVPER GRMDVAEPYK VYQLLPPGIV 
SGQPGTQKVP SKRQHSSVSS ERKEEEDAMQ NCTLSPSVLQ DSLNNEEEGA SGGAVHSDIG 
SSSSSSSPEP QEVTDTTEAP FQGDQRSLEF LLPPEPDYSL LLTFIYNGRV VGEAQVQSLD 
CRLVAEPSGS ESSMEQVLFP KPGPLEPTQR LLSQLERGIL VASNPRGLFV QRLCPIPISW 
NAPQAPPGPG PHLLPSNECV ELFRTAYFCR DLVRYFQGLG PPPKFQVTLN FWEESHGSSH 
TPQNLITVKM EQAFARYLLE QTPEQQAAIL SLV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: IRF9

Associated with

Other Information

Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins. PubMed ID: 1630447

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Nuclear/cytoplasmic localization of IRFs in response to viral infection or interferon stimulation. PubMed ID: 11846981

Viral inhibition of interferon signal transduction. PubMed ID: 10702714

Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency. PubMed ID: 30143481

Impaired control of multiple viral infections in a family with complete IRF9 deficiency. PubMed ID: 30826365

Herpes Simplex Virus Type 2 Inhibits Type I IFN Signaling Mediated by the Novel E3 Ubiquitin Protein Ligase Activity of Viral Protein ICP22. PubMed ID: 32699158