Details for: BTN2A2

Gene ID: 10385

Symbol: BTN2A2

Ensembl ID: ENSG00000124508

Description: butyrophilin subfamily 2 member A2

Associated with

  • Adaptive immune system
    (R-HSA-1280218)
  • Butyrophilin (btn) family interactions
    (R-HSA-8851680)
  • Immune system
    (R-HSA-168256)
  • Erk1 and erk2 cascade
    (GO:0070371)
  • External side of plasma membrane
    (GO:0009897)
  • G1/s transition of mitotic cell cycle
    (GO:0000082)
  • Negative regulation of activated t cell proliferation
    (GO:0046007)
  • Negative regulation of cytokine production
    (GO:0001818)
  • Negative regulation of erk1 and erk2 cascade
    (GO:0070373)
  • Negative regulation of g1/s transition of mitotic cell cycle
    (GO:2000134)
  • Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051898)
  • Negative regulation of t cell receptor signaling pathway
    (GO:0050860)
  • Phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0043491)
  • Plasma membrane
    (GO:0005886)
  • Positive regulation of regulatory t cell differentiation
    (GO:0045591)
  • Protein binding
    (GO:0005515)
  • Regulation of cytokine production
    (GO:0001817)
  • Signaling receptor binding
    (GO:0005102)
  • T cell receptor signaling pathway
    (GO:0050852)

Other Information

Genular Protein ID: 556248097

Symbol: BT2A2_HUMAN

Name: Butyrophilin subfamily 2 member A2

UniProtKB Accession Codes:

Q8WVV5 A6NM84 B4DE97 B4DQ01 E9PH07 O00480

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EPD 1 Ensembl 6 ExpressionAtlas 1 GO 15 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 1 RefSeq 12 SMART 4 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9149941

Title: A 1.1-Mb transcript map of the hereditary hemochromatosis locus.

PubMed ID: 9149941

DOI: 10.1101/gr.7.5.441

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 523
  • Mass: 59070
  • Checksum: 122099CE635F279D
  • Sequence:
    • MEPAAALHFS LPASLLLLLL LLLLSLCALV SAQFTVVGPA NPILAMVGEN TTLRCHLSPE 
KNAEDMEVRW FRSQFSPAVF VYKGGRERTE EQMEEYRGRI TFVSKDINRG SVALVIHNVT 
AQENGIYRCY FQEGRSYDEA ILRLVVAGLG SKPLIEIKAQ EDGSIWLECI SGGWYPEPLT 
VWRDPYGEVV PALKEVSIAD ADGLFMVTTA VIIRDKYVRN VSCSVNNTLL GQEKETVIFI 
PESFMPSASP WMVALAVILT ASPWMVSMTV ILAVFIIFMA VSICCIKKLQ REKKILSGEK 
KVEQEEKEIA QQLQEELRWR RTFLHAADVV LDPDTAHPEL FLSEDRRSVR RGPYRQRVPD 
NPERFDSQPC VLGWESFASG KHYWEVEVEN VMVWTVGVCR HSVERKGEVL LIPQNGFWTL 
EMFGNQYRAL SSPERILPLK ESLCRVGVFL DYEAGDVSFY NMRDRSHIYT CPRSAFTVPV 
RPFFRLGSDD SPIFICPALT GASGVMVPEE GLKLHRVGTH QSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.