Details for: NOD1

Gene ID: 10392

Symbol: NOD1

Ensembl ID: ENSG00000106100

Description: nucleotide binding oligomerization domain containing 1

Associated with

Other Information

Genular Protein ID: 1241777323

Symbol: NOD1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10224040

Title: Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB.

PubMed ID: 10224040

DOI: 10.1074/jbc.274.19.12955

PubMed ID: 10329646

Title: Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB.

PubMed ID: 10329646

DOI: 10.1074/jbc.274.21.14560

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10880512

Title: An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways.

PubMed ID: 10880512

DOI: 10.1074/jbc.m003415200

PubMed ID: 11058605

Title: Human Nod1 confers responsiveness to bacterial lipopolysaccharides.

PubMed ID: 11058605

DOI: 10.1074/jbc.m009728200

PubMed ID: 12871942

Title: Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.

PubMed ID: 12871942

DOI: 10.1074/jbc.m307198200

PubMed ID: 12796777

Title: An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid.

PubMed ID: 12796777

DOI: 10.1038/ni945

PubMed ID: 12791997

Title: Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan.

PubMed ID: 12791997

DOI: 10.1126/science.1084677

PubMed ID: 15044951

Title: Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition.

PubMed ID: 15044951

DOI: 10.1038/sj.emboj.7600175

PubMed ID: 16211083

Title: Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin.

PubMed ID: 16211083

DOI: 10.1038/sj.embor.7400552

PubMed ID: 16172124

Title: Identification of the critical residues involved in peptidoglycan detection by Nod1.

PubMed ID: 16172124

DOI: 10.1074/jbc.m509537200

PubMed ID: 17970764

Title: The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction.

PubMed ID: 17970764

DOI: 10.1111/j.1462-5822.2007.01062.x

PubMed ID: 19043560

Title: GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors.

PubMed ID: 19043560

DOI: 10.1371/journal.ppat.1000228

PubMed ID: 22672233

Title: NLRP10 enhances Shigella-induced pro-inflammatory responses.

PubMed ID: 22672233

DOI: 10.1111/j.1462-5822.2012.01822.x

PubMed ID: 23300079

Title: Ubiquitin regulates caspase recruitment domain-mediated signaling by nucleotide-binding oligomerization domain-containing proteins NOD1 and NOD2.

PubMed ID: 23300079

DOI: 10.1074/jbc.m112.413781

PubMed ID: 25012219

Title: The E3 ligase RNF34 is a novel negative regulator of the NOD1 pathway.

PubMed ID: 25012219

DOI: 10.1159/000362972

PubMed ID: 27099311

Title: NOD1 Participates in the Innate Immune Response Triggered by Hepatitis C Virus Polymerase.

PubMed ID: 27099311

DOI: 10.1128/jvi.03230-15

PubMed ID: 27007849

Title: NOD1 and NOD2 signalling links ER stress with inflammation.

PubMed ID: 27007849

DOI: 10.1038/nature17631

PubMed ID: 30478312

Title: Structural basis of RIP2 activation and signaling.

PubMed ID: 30478312

DOI: 10.1038/s41467-018-07447-9

PubMed ID: 31649195

Title: Palmitoylation of NOD1 and NOD2 is required for bacterial sensing.

PubMed ID: 31649195

DOI: 10.1126/science.aau6391

PubMed ID: 32169843

Title: NOD1 Promotes Antiviral Signaling by Binding Viral RNA and Regulating the Interaction of MDA5 and MAVS.

PubMed ID: 32169843

DOI: 10.4049/jimmunol.1900667

PubMed ID: 33942347

Title: Cellular stress promotes NOD1/2-dependent inflammation via the endogenous metabolite sphingosine-1-phosphate.

PubMed ID: 33942347

DOI: 10.15252/embj.2020106272

PubMed ID: 36221902

Title: Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection.

PubMed ID: 36221902

DOI: 10.15252/embj.2022111289

PubMed ID: 17173864

Title: Crystal structure of the Nod1 caspase activation and recruitment domain.

PubMed ID: 17173864

DOI: 10.1016/j.bbrc.2006.11.122

PubMed ID: 17054981

Title: Solution structure of NOD1 CARD and mutational analysis of its interaction with the CARD of downstream kinase RICK.

PubMed ID: 17054981

DOI: 10.1016/j.jmb.2006.09.067

PubMed ID: 18186648

Title: Monomer/dimer transition of the caspase-recruitment domain of human Nod1.

PubMed ID: 18186648

DOI: 10.1021/bi7016602

PubMed ID: 25127239

Title: Crystal structure of a complex of NOD1 CARD and ubiquitin.

PubMed ID: 25127239

DOI: 10.1371/journal.pone.0104017

Sequence Information:

  • Length: 953
  • Mass: 107691
  • Checksum: 0A9DF5FC6487E21A
  • Sequence:
  • MEEQGHSEME IIPSESHPHI QLLKSNRELL VTHIRNTQCL VDNLLKNDYF SAEDAEIVCA 
    CPTQPDKVRK ILDLVQSKGE EVSEFFLYLL QQLADAYVDL RPWLLEIGFS PSLLTQSKVV 
    VNTDPVSRYT QQLRHHLGRD SKFVLCYAQK EELLLEEIYM DTIMELVGFS NESLGSLNSL 
    ACLLDHTTGI LNEQGETIFI LGDAGVGKSM LLQRLQSLWA TGRLDAGVKF FFHFRCRMFS 
    CFKESDRLCL QDLLFKHYCY PERDPEEVFA FLLRFPHVAL FTFDGLDELH SDLDLSRVPD 
    SSCPWEPAHP LVLLANLLSG KLLKGASKLL TARTGIEVPR QFLRKKVLLR GFSPSHLRAY 
    ARRMFPERAL QDRLLSQLEA NPNLCSLCSV PLFCWIIFRC FQHFRAAFEG SPQLPDCTMT 
    LTDVFLLVTE VHLNRMQPSS LVQRNTRSPV ETLHAGRDTL CSLGQVAHRG MEKSLFVFTQ 
    EEVQASGLQE RDMQLGFLRA LPELGPGGDQ QSYEFFHLTL QAFFTAFFLV LDDRVGTQEL 
    LRFFQEWMPP AGAATTSCYP PFLPFQCLQG SGPAREDLFK NKDHFQFTNL FLCGLLSKAK 
    QKLLRHLVPA AALRRKRKAL WAHLFSSLRG YLKSLPRVQV ESFNQVQAMP TFIWMLRCIY 
    ETQSQKVGQL AARGICANYL KLTYCNACSA DCSALSFVLH HFPKRLALDL DNNNLNDYGV 
    RELQPCFSRL TVLRLSVNQI TDGGVKVLSE ELTKYKIVTY LGLYNNQITD VGARYVTKIL 
    DECKGLTHLK LGKNKITSEG GKYLALAVKN SKSISEVGMW GNQVGDEGAK AFAEALRNHP 
    SLTTLSLASN GISTEGGKSL ARALQQNTSL EILWLTQNEL NDEVAESLAE MLKVNQTLKH 
    LWLIQNQITA KGTAQLADAL QSNTGITEIC LNGNLIKPEE AKVYEDEKRI ICF

Genular Protein ID: 112292306

Symbol: G3XAL1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

Sequence Information:

  • Length: 779
  • Mass: 88842
  • Checksum: 06801B8E4730A1D6
  • Sequence:
  • MEEQGHSEME IIPSESHPHI QLLKSNRELL VTHIRNTQCL VDNLLKNDYF SAEDAEIVCA 
    CPTQPDKVRK ILDLVQSKGE EVSEFFLYLL QQLADAYVDL RPWLLEIGFS PSLLTQSKVV 
    VNTDPVSRYT QQLRHHLGRD SKFVLCYAQK EELLLEEIYM DTIMELVGFS NESLGSLNSL 
    ACLLDHTTGI LNEQGETIFI LGDAGVGKSM LLQRLQSLWA TGRLDAGVKF FFHFRCRMFS 
    CFKESDRLCL QDLLFKHYCY PERDPEEVFA FLLRFPHVAL FTFDGLDELH SDLDLSRVPD 
    SSCPWEPAHP LVLLANLLSG KLLKGASKLL TARTGIEVPR QFLRKKVLLR GFSPSHLRAY 
    ARRMFPERAL QDRLLSQLEA NPNLCSLCSV PLFCWIIFRC FQHFRAAFEG SPQLPDCTMT 
    LTDVFLLVTE VHLNRMQPSS LVQRNTRSPV ETLHAGRDTL CSLGQVAHRG MEKSLFVFTQ 
    EEVQASGLQE RDMQLGFLRA LPELGPGGDQ QSYEFFHLTL QAFFTAFFLV LDDRVGTQEL 
    LRFFQEWMPP AGAATTSCYP PFLPFQCLQG SGPAREDLFK NKDHFQFTNL FLCGLLSKAK 
    QKLLRHLVPA AALRRKRKAL WAHLFSSLRG YLKSLPRVQV ESFNQVQAMP TFIWMLRCIY 
    ETQSQKVGQL AARGICANYL KLTYCNACSA DCSALSFVLH HFPKRLALDL DNNNLNDYGV 
    RELQPCFSRL TVLRLSVNQI TDGGVKVLSE ELTKYKIVTY LGLWKSVDTI CFKKQGLLK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.