Details for: NDRG1

Gene ID: 10397

Symbol: NDRG1

Ensembl ID: ENSG00000104419

Description: N-myc downstream regulated 1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 3.41
    Marker Score: 8,596
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 2.88
    Marker Score: 22,496
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.65
    Marker Score: 2,793
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 2.59
    Marker Score: 1,997
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 2.58
    Marker Score: 1,503
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 2.52
    Marker Score: 7,907
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 2.41
    Marker Score: 1,376
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.34
    Marker Score: 3,445
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 2.29
    Marker Score: 775
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 2.28
    Marker Score: 886
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 2.26
    Marker Score: 4,003
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 2.2
    Marker Score: 3,200
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 2.18
    Marker Score: 1,719
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 2.18
    Marker Score: 13,915
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 2.18
    Marker Score: 3,079
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 2.1
    Marker Score: 5,024
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 2.06
    Marker Score: 9,869
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 2.04
    Marker Score: 2,159
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 1.93
    Marker Score: 16,599
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 1.92
    Marker Score: 2,958
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.91
    Marker Score: 2,042
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.91
    Marker Score: 64,937
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.88
    Marker Score: 2,431
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.84
    Marker Score: 1,099
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 1.84
    Marker Score: 3,045
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 1.83
    Marker Score: 2,207
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.79
    Marker Score: 443
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.76
    Marker Score: 406
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 1.74
    Marker Score: 3,470
  • Cell Name: intestine goblet cell (CL0019031)
    Fold Change: 1.73
    Marker Score: 1,655
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.72
    Marker Score: 1,899
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 1.71
    Marker Score: 1,532
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.67
    Marker Score: 5,918
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.66
    Marker Score: 520
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.65
    Marker Score: 2,058
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 1.62
    Marker Score: 3,686
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.61
    Marker Score: 2,717
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.6
    Marker Score: 2,158
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.58
    Marker Score: 1,577
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 1.57
    Marker Score: 687
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 1.56
    Marker Score: 376
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 1.56
    Marker Score: 1,411
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.56
    Marker Score: 3,549
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.55
    Marker Score: 1,376
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: 1.54
    Marker Score: 327
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 1.54
    Marker Score: 1,310
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 1.51
    Marker Score: 7,929
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.47
    Marker Score: 3,455
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 1.44
    Marker Score: 1,355
  • Cell Name: peritubular capillary endothelial cell (CL1001033)
    Fold Change: 1.42
    Marker Score: 331
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 1.42
    Marker Score: 534
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 1.42
    Marker Score: 1,183
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.41
    Marker Score: 826
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.4
    Marker Score: 3,317
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.39
    Marker Score: 3,407
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.39
    Marker Score: 3,458
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.39
    Marker Score: 3,718
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 1.38
    Marker Score: 310
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 1.37
    Marker Score: 388
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 1.37
    Marker Score: 570
  • Cell Name: epithelial cell of stratum germinativum of esophagus (CL1000447)
    Fold Change: 1.36
    Marker Score: 329
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.35
    Marker Score: 2,593
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 1.34
    Marker Score: 1,153
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 1.31
    Marker Score: 264
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.3
    Marker Score: 2,850
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.3
    Marker Score: 640
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.28
    Marker Score: 891
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 1.26
    Marker Score: 3,298
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.26
    Marker Score: 1,425
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.24
    Marker Score: 1,075
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 1.24
    Marker Score: 555
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.24
    Marker Score: 305
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.23
    Marker Score: 26,221
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.23
    Marker Score: 19,213
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.23
    Marker Score: 675
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 1.22
    Marker Score: 240
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 1.22
    Marker Score: 762
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 1.22
    Marker Score: 571
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.22
    Marker Score: 351
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.21
    Marker Score: 5,207
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 1.2
    Marker Score: 2,184
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 1.19
    Marker Score: 278
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.18
    Marker Score: 666
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.17
    Marker Score: 2,218
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.16
    Marker Score: 1,102
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 1.15
    Marker Score: 1,352
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.15
    Marker Score: 1,244
  • Cell Name: pericyte (CL0000669)
    Fold Change: 1.15
    Marker Score: 673
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.15
    Marker Score: 425
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.14
    Marker Score: 329
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 1.14
    Marker Score: 1,819
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.14
    Marker Score: 362
  • Cell Name: peptic cell (CL0000155)
    Fold Change: 1.13
    Marker Score: 473
  • Cell Name: vasa recta ascending limb cell (CL1001131)
    Fold Change: 1.13
    Marker Score: 298
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.12
    Marker Score: 7,271
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.11
    Marker Score: 3,643
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: 1.11
    Marker Score: 413
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 1.1
    Marker Score: 266
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 1.1
    Marker Score: 1,103
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.09
    Marker Score: 352

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** NDRG1 is a member of the n-myc downstream-regulated (NDR) gene family, which is involved in regulating cell growth, differentiation, and survival. The protein encoded by NDRG1 is a 28-kDa protein that is highly expressed in epithelial cells, fibroblasts, and stem cells. It is characterized by its ability to inhibit cell proliferation, promote differentiation, and induce apoptosis in response to cellular stress. NDRG1 is also involved in regulating the expression of other genes, including those involved in cell cycle regulation, apoptosis, and DNA repair. **Pathways and Functions:** NDRG1 is involved in several cellular pathways that regulate cell growth, differentiation, and survival. These pathways include: 1. **Adherens Junction**: NDRG1 regulates the expression of genes involved in adherens junction formation, which is critical for maintaining tissue structure and integrity. 2. **Signal Transduction by p53**: NDRG1 is a target gene of p53, a tumor suppressor protein that regulates cell growth, differentiation, and survival. NDRG1 promotes apoptosis in response to p53-induced stress. 3. **DNA Damage Response**: NDRG1 regulates the expression of genes involved in DNA repair and cell cycle arrest, which is critical for maintaining genome stability. 4. **Microtubule Cytoskeleton**: NDRG1 regulates the expression of genes involved in microtubule formation and stabilization, which is critical for maintaining cellular structure and function. **Clinical Significance:** NDRG1 has been implicated in various diseases, including: 1. **Cancer**: NDRG1 is frequently downregulated in various types of cancer, including breast, lung, and colon cancer. Its restoration has been shown to inhibit tumor growth and promote apoptosis. 2. **Neurodegenerative Disorders**: NDRG1 has been implicated in neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. Its dysregulation has been shown to contribute to neuronal loss and cognitive decline. 3. **Cardiovascular Diseases**: NDRG1 has been implicated in cardiovascular diseases, including atherosclerosis and heart failure. Its dysregulation has been shown to contribute to vascular remodeling and cardiac dysfunction. **Therapeutic Applications:** NDRG1 has potential therapeutic applications in the treatment of various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Its restoration has been shown to inhibit tumor growth, promote apoptosis, and improve cellular function. Potential therapeutic strategies include: 1. **Gene Therapy**: NDRG1 gene therapy has been shown to restore its expression in cancer cells, inhibiting tumor growth and promoting apoptosis. 2. **Small Molecule Inhibitors**: Small molecule inhibitors of NDRG1 have been shown to promote its degradation, inhibiting its tumor-suppressive functions. 3. **Pharmacological Restoration**: Pharmacological restoration of NDRG1 expression has been shown to improve cellular function and reduce disease severity in various models of disease. In conclusion, NDRG1 is a multifaceted gene that plays a critical role in maintaining cellular homeostasis. Its dysregulation has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Further research is needed to fully understand its mechanisms of action and to develop effective therapeutic strategies for its restoration.

Genular Protein ID: 152759126

Symbol: NDRG1_HUMAN

Name: Protein NDRG1

UniProtKB Accession Codes:

Q92597 B3KR80 B7Z446 O15207 Q6IBG2 Q9NYR6 Q9UK29

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 EPD 1 ESTHER 1 Ensembl 3 ExpressionAtlas 1 GO 22 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SAM 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8939898

Title: Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes.

PubMed ID: 8939898

DOI: 10.1074/jbc.271.47.29659

PubMed ID: 9251681

Title: A novel gene which is up-regulated during colon epithelial cell differentiation and down-regulated in colorectal neoplasms.

PubMed ID: 9251681

PubMed ID: 9605764

Title: Cap43, a novel gene specifically induced by Ni2+ compounds.

PubMed ID: 9605764

PubMed ID: 10395947

Title: Differential expression of the RTP/Drg1/Ndr1 gene product in proliferating and growth arrested cells.

PubMed ID: 10395947

DOI: 10.1016/s0167-4889(99)00056-7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9766676

Title: Inhibition of tumor cell growth by RTP/rit42 and its responsiveness to p53 and DNA damage.

PubMed ID: 9766676

PubMed ID: 10831399

Title: N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom.

PubMed ID: 10831399

DOI: 10.1086/302978

PubMed ID: 10860807

Title: Phosphorylation of RTP, an ER stress-responsive cytoplasmic protein.

PubMed ID: 10860807

DOI: 10.1006/bbrc.2000.2833

PubMed ID: 12432451

Title: Expression of NDRG1, a differentiation-related gene, in human tissues.

PubMed ID: 12432451

DOI: 10.1007/s00418-002-0460-9

PubMed ID: 15461589

Title: Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3.

PubMed ID: 15461589

DOI: 10.1042/bj20041057

PubMed ID: 15247272

Title: Function of Drg1/Rit42 in p53-dependent mitotic spindle checkpoint.

PubMed ID: 15247272

DOI: 10.1074/jbc.m400781200

PubMed ID: 15377670

Title: NDRG1 is necessary for p53-dependent apoptosis.

PubMed ID: 15377670

DOI: 10.1074/jbc.m400386200

PubMed ID: 15922294

Title: NDRG1 interacts with APO A-I and A-II and is a functional candidate for the HDL-C QTL on 8q24.

PubMed ID: 15922294

DOI: 10.1016/j.bbrc.2005.05.050

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 17316623

Title: Hypoxia increases cytoplasmic expression of NDRG1, but is insufficient for its membrane localization in human hepatocellular carcinoma.

PubMed ID: 17316623

DOI: 10.1016/j.febslet.2007.01.080

PubMed ID: 17786215

Title: The N-Myc down regulated Gene1 (NDRG1) is a Rab4a effector involved in vesicular recycling of E-cadherin.

PubMed ID: 17786215

DOI: 10.1371/journal.pone.0000844

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 18787837

Title: SGK1 activity in Na+ absorbing airway epithelial cells monitored by assaying NDRG1-Thr346/356/366 phosphorylation.

PubMed ID: 18787837

DOI: 10.1007/s00424-008-0587-1

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21708134

Title: Phosphorylation of NDRG1 is temporally and spatially controlled during the cell cycle.

PubMed ID: 21708134

DOI: 10.1016/j.bbrc.2011.06.092

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 394
  • Mass: 42835
  • Checksum: 4C816B9C85E3756F
  • Sequence:
    • MSREMQDVDL AEVKPLVEKG ETITGLLQEF DVQEQDIETL HGSVHVTLCG TPKGNRPVIL 
TYHDIGMNHK TCYNPLFNYE DMQEITQHFA VCHVDAPGQQ DGAASFPAGY MYPSMDQLAE 
MLPGVLQQFG LKSIIGMGTG AGAYILTRFA LNNPEMVEGL VLINVNPCAE GWMDWAASKI 
SGWTQALPDM VVSHLFGKEE MQSNVEVVHT YRQHIVNDMN PGNLHLFINA YNSRRDLEIE 
RPMPGTHTVT LQCPALLVVG DSSPAVDAVV ECNSKLDPTK TTLLKMADCG GLPQISQPAK 
LAEAFKYFVQ GMGYMPSASM TRLMRSRTAS GSSVTSLDGT RSRSHTSEGT RSRSHTSEGT 
RSRSHTSEGA HLDITPNSGA AGNSAGPKSM EVSC

Genular Protein ID: 1602540958

Symbol: Q8N959_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8N959

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 ESTHER 1 Gene3D 1 GenomeRNAi 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 2 SAM 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 323
  • Mass: 35226
  • Checksum: EA130D129F3B92E8
  • Sequence:
    • MSREMQDVDL AEVKPLVEKG ETITGLLQEF DVQEQDIETL HGSVHVTLCG TPKGNRPVIL 
TYHDIGMNHK TCYILTRFAL NNPEMVEGLV LINVNPCAEG WMDWAASKIS GWTQALPDMV 
VSHLFGKEEM QSNVEVVHTY RQHIVNDMNP GNLHLFINAY NSRRDLEIER PMPGTHTVTL 
QCPALLVVGD SSPAVDAVVE CNSKLDPTKT TLLKMADCGG LPQISQPAKL AEAFKYFVQG 
MGYMPSASMT RLMRSRTASG SSVTSLDGTR SRSHTSEGTR SRSHTSEGTR SRSHTSEGAH 
LDITPNSGAA GNSAGPKSME VSC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.