Details for: NDRG1

Gene ID: 10397

Symbol: NDRG1

Ensembl ID: ENSG00000104419

Description: N-myc downstream regulated 1

Associated with

Other Information

Genular Protein ID: 152759126

Symbol: NDRG1_HUMAN

Name: Protein NDRG1

UniProtKB Accession Codes:

Q92597 B3KR80 B7Z446 O15207 Q6IBG2 Q9NYR6 Q9UK29

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 EPD 1 ESTHER 1 Ensembl 3 ExpressionAtlas 1 GO 22 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SAM 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8939898

Title: Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes.

PubMed ID: 8939898

DOI: 10.1074/jbc.271.47.29659

PubMed ID: 9251681

Title: A novel gene which is up-regulated during colon epithelial cell differentiation and down-regulated in colorectal neoplasms.

PubMed ID: 9251681

PubMed ID: 9605764

Title: Cap43, a novel gene specifically induced by Ni2+ compounds.

PubMed ID: 9605764

PubMed ID: 10395947

Title: Differential expression of the RTP/Drg1/Ndr1 gene product in proliferating and growth arrested cells.

PubMed ID: 10395947

DOI: 10.1016/s0167-4889(99)00056-7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9766676

Title: Inhibition of tumor cell growth by RTP/rit42 and its responsiveness to p53 and DNA damage.

PubMed ID: 9766676

PubMed ID: 10831399

Title: N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom.

PubMed ID: 10831399

DOI: 10.1086/302978

PubMed ID: 10860807

Title: Phosphorylation of RTP, an ER stress-responsive cytoplasmic protein.

PubMed ID: 10860807

DOI: 10.1006/bbrc.2000.2833

PubMed ID: 12432451

Title: Expression of NDRG1, a differentiation-related gene, in human tissues.

PubMed ID: 12432451

DOI: 10.1007/s00418-002-0460-9

PubMed ID: 15461589

Title: Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3.

PubMed ID: 15461589

DOI: 10.1042/bj20041057

PubMed ID: 15247272

Title: Function of Drg1/Rit42 in p53-dependent mitotic spindle checkpoint.

PubMed ID: 15247272

DOI: 10.1074/jbc.m400781200

PubMed ID: 15377670

Title: NDRG1 is necessary for p53-dependent apoptosis.

PubMed ID: 15377670

DOI: 10.1074/jbc.m400386200

PubMed ID: 15922294

Title: NDRG1 interacts with APO A-I and A-II and is a functional candidate for the HDL-C QTL on 8q24.

PubMed ID: 15922294

DOI: 10.1016/j.bbrc.2005.05.050

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 17316623

Title: Hypoxia increases cytoplasmic expression of NDRG1, but is insufficient for its membrane localization in human hepatocellular carcinoma.

PubMed ID: 17316623

DOI: 10.1016/j.febslet.2007.01.080

PubMed ID: 17786215

Title: The N-Myc down regulated Gene1 (NDRG1) is a Rab4a effector involved in vesicular recycling of E-cadherin.

PubMed ID: 17786215

DOI: 10.1371/journal.pone.0000844

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 18787837

Title: SGK1 activity in Na+ absorbing airway epithelial cells monitored by assaying NDRG1-Thr346/356/366 phosphorylation.

PubMed ID: 18787837

DOI: 10.1007/s00424-008-0587-1

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21708134

Title: Phosphorylation of NDRG1 is temporally and spatially controlled during the cell cycle.

PubMed ID: 21708134

DOI: 10.1016/j.bbrc.2011.06.092

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 394
  • Mass: 42835
  • Checksum: 4C816B9C85E3756F
  • Sequence:
    • MSREMQDVDL AEVKPLVEKG ETITGLLQEF DVQEQDIETL HGSVHVTLCG TPKGNRPVIL 
TYHDIGMNHK TCYNPLFNYE DMQEITQHFA VCHVDAPGQQ DGAASFPAGY MYPSMDQLAE 
MLPGVLQQFG LKSIIGMGTG AGAYILTRFA LNNPEMVEGL VLINVNPCAE GWMDWAASKI 
SGWTQALPDM VVSHLFGKEE MQSNVEVVHT YRQHIVNDMN PGNLHLFINA YNSRRDLEIE 
RPMPGTHTVT LQCPALLVVG DSSPAVDAVV ECNSKLDPTK TTLLKMADCG GLPQISQPAK 
LAEAFKYFVQ GMGYMPSASM TRLMRSRTAS GSSVTSLDGT RSRSHTSEGT RSRSHTSEGT 
RSRSHTSEGA HLDITPNSGA AGNSAGPKSM EVSC

Genular Protein ID: 1602540958

Symbol: Q8N959_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8N959

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 ESTHER 1 Gene3D 1 GenomeRNAi 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 2 SAM 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 323
  • Mass: 35226
  • Checksum: EA130D129F3B92E8
  • Sequence:
    • MSREMQDVDL AEVKPLVEKG ETITGLLQEF DVQEQDIETL HGSVHVTLCG TPKGNRPVIL 
TYHDIGMNHK TCYILTRFAL NNPEMVEGLV LINVNPCAEG WMDWAASKIS GWTQALPDMV 
VSHLFGKEEM QSNVEVVHTY RQHIVNDMNP GNLHLFINAY NSRRDLEIER PMPGTHTVTL 
QCPALLVVGD SSPAVDAVVE CNSKLDPTKT TLLKMADCGG LPQISQPAKL AEAFKYFVQG 
MGYMPSASMT RLMRSRTASG SSVTSLDGTR SRSHTSEGTR SRSHTSEGTR SRSHTSEGAH 
LDITPNSGAA GNSAGPKSME VSC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.