Details for: PEMT

Gene ID: 10400

Symbol: PEMT

Ensembl ID: ENSG00000133027

Description: phosphatidylethanolamine N-methyltransferase

Associated with

Other Information

Genular Protein ID: 1274385929

Symbol: PEMT_HUMAN

Name: PEMT2

UniProtKB Accession Codes:

Q9UBM1 A8MZ66 B4DY41 D3DXC3 Q6IAQ5 Q86VL3 Q9BW86 Q9UHY6 Q9Y6V9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChEBI 92 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 6 EMBL 18 Ensembl 4 ExpressionAtlas 1 GO 14 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HAMAP 1 HAMAP-Rule 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 5 Rhea 36 STRING 1 SignaLink 1 SwissLipids 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9989271

Title: Identification of three novel cDNAs for human phosphatidylethanolamine N-methyltransferase and localization of the human gene on chromosome 17p11.2.

PubMed ID: 9989271

DOI: 10.1016/s0005-2760(98)00147-7

PubMed ID: 11420179

Title: Structure, expression profile and alternative processing of the human phosphatidylethanolamine N-methyltransferase (PEMT) gene.

PubMed ID: 11420179

DOI: 10.1016/s1388-1981(01)00122-6

PubMed ID: 10931946

Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.

PubMed ID: 10931946

DOI: 10.1073/pnas.160270997

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12431977

Title: Membrane topography of human phosphatidylethanolamine N-methyltransferase.

PubMed ID: 12431977

DOI: 10.1074/jbc.m210904200

PubMed ID: 12842883

Title: Molecular dissection of the S-adenosylmethionine-binding site of phosphatidylethanolamine N-methyltransferase.

PubMed ID: 12842883

DOI: 10.1074/jbc.m306308200

PubMed ID: 15927961

Title: Localization-independent regulation of homocysteine secretion by phosphatidylethanolamine N-methyltransferase.

PubMed ID: 15927961

DOI: 10.1074/jbc.m504658200

PubMed ID: 17456783

Title: Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes.

PubMed ID: 17456783

DOI: 10.1096/fj.07-8227com

PubMed ID: 20860552

Title: Functional analysis of two isoforms of phosphatidylethanolamine N-methyltransferase.

PubMed ID: 20860552

DOI: 10.1042/bj20100490

Sequence Information:

  • Length: 199
  • Mass: 22134
  • Checksum: 98C07AB54B3B4E6A
  • Sequence:
    • MTRLLGYVDP LDPSFVAAVI TITFNPLYWN VVARWEHKTR KLSRAFGSPY LACYSLSVTI 
LLLNFLRSHC FTQAMLSQPR MESLDTPAAY SLGLALLGLG VVLVLSSFFA LGFAGTFLGD 
YFGILKEARV TVFPFNILDN PMYWGSTANY LGWAIMHASP TGLLLTVLVA LTYIVALLYE 
EPFTAEIYRQ KASGSHKRS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.