Details for: NDC80

Gene ID: 10403

Symbol: NDC80

Ensembl ID: ENSG00000080986

Description: NDC80 kinetochore complex component

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 1.32
    Marker Score: 3,576
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 1.23
    Marker Score: 1,155
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.14
    Marker Score: 2,317
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,801
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,026
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,406
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.96
    Marker Score: 495
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.96
    Marker Score: 1,815
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.95
    Marker Score: 449
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,410
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,732
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.9
    Marker Score: 361
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.9
    Marker Score: 5,128
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.88
    Marker Score: 315
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,276
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.82
    Marker Score: 1,402
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.8
    Marker Score: 2,388
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 0.8
    Marker Score: 850
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.77
    Marker Score: 1,252
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.74
    Marker Score: 384
  • Cell Name: gut endothelial cell (CL0000131)
    Fold Change: 0.73
    Marker Score: 261
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.71
    Marker Score: 541
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 0.7
    Marker Score: 1,003
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.69
    Marker Score: 632
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.68
    Marker Score: 851
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 0.68
    Marker Score: 426
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.67
    Marker Score: 506
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.67
    Marker Score: 172
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.67
    Marker Score: 2,800
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.66
    Marker Score: 871
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.61
    Marker Score: 9,582
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.61
    Marker Score: 616
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 0.57
    Marker Score: 322
  • Cell Name: fetal cardiomyocyte (CL0002495)
    Fold Change: 0.57
    Marker Score: 186
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.55
    Marker Score: 441
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.54
    Marker Score: 174
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.53
    Marker Score: 3,180
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 0.52
    Marker Score: 276
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.51
    Marker Score: 161
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 0.48
    Marker Score: 277
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.48
    Marker Score: 348
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.47
    Marker Score: 573
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.44
    Marker Score: 220
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.44
    Marker Score: 922
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 0.43
    Marker Score: 230
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.41
    Marker Score: 129
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.41
    Marker Score: 1,110
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 0.4
    Marker Score: 194
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.39
    Marker Score: 104
  • Cell Name: pre-conventional dendritic cell (CL0002010)
    Fold Change: 0.39
    Marker Score: 115
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 0.39
    Marker Score: 192
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 0.39
    Marker Score: 143
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.38
    Marker Score: 238
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.38
    Marker Score: 893
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 0.37
    Marker Score: 108
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 0.37
    Marker Score: 3,667
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.37
    Marker Score: 117
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.37
    Marker Score: 356
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.36
    Marker Score: 855
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.36
    Marker Score: 149
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.36
    Marker Score: 1,398
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.35
    Marker Score: 168
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.35
    Marker Score: 177
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 0.35
    Marker Score: 988
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.35
    Marker Score: 370
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.34
    Marker Score: 218
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.34
    Marker Score: 203
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: 0.34
    Marker Score: 93
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.33
    Marker Score: 160
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.33
    Marker Score: 115
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.32
    Marker Score: 92
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 0.32
    Marker Score: 305
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.32
    Marker Score: 135
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.32
    Marker Score: 1,316
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 0.32
    Marker Score: 1,326
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.32
    Marker Score: 215
  • Cell Name: mature B cell (CL0000785)
    Fold Change: 0.31
    Marker Score: 228
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.31
    Marker Score: 257
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.3
    Marker Score: 317
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 0.29
    Marker Score: 204
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 0.29
    Marker Score: 99
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 0.28
    Marker Score: 544
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 0.28
    Marker Score: 3,634
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.28
    Marker Score: 176
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 0.27
    Marker Score: 286
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.27
    Marker Score: 261
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.27
    Marker Score: 180
  • Cell Name: interstitial cell of Cajal (CL0002088)
    Fold Change: 0.27
    Marker Score: 94
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 0.27
    Marker Score: 379
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: 0.26
    Marker Score: 145
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: 0.26
    Marker Score: 73
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.26
    Marker Score: 64
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 0.26
    Marker Score: 2,173
  • Cell Name: stem cell (CL0000034)
    Fold Change: 0.25
    Marker Score: 598
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.25
    Marker Score: 222
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.24
    Marker Score: 143
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.24
    Marker Score: 270
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 0.24
    Marker Score: 48
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.23
    Marker Score: 108
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.23
    Marker Score: 105

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** NDC80 is a member of the NDC80 complex, which is a heterotrimeric complex consisting of NDC80, NDC80B, and NDC80C. This complex is specifically localized to the outer kinetochore, a region of the kinetochore that interacts with microtubules. NDC80 is a highly conserved protein across species, with high sequence similarity to its counterparts in other organisms. **Pathways and Functions:** The NDC80 complex plays a central role in the amplification of signals from the kinetochore, which is essential for the proper attachment and separation of chromosomes during mitosis. The complex interacts with microtubules, regulating the assembly and disassembly of mitotic spindles. Additionally, NDC80 is involved in the regulation of protein stability, cell cycle checkpoints, and the resolution of sister chromatid cohesion. The NDC80 complex is also implicated in the regulation of spindle assembly checkpoint signaling, ensuring that chromosomes are properly attached to the spindle before anaphase onset. Furthermore, NDC80 has been shown to interact with various signaling pathways, including those involving Rho GTPases, which play a critical role in regulating cell division. **Clinical Significance:** Dysregulation of the NDC80 complex has been implicated in various human diseases, including cancer. Mutations in the NDC80 gene have been associated with an increased risk of cancer, particularly in the context of mitotic spindle assembly errors. Additionally, abnormalities in the NDC80 complex have been observed in patients with certain genetic disorders, such as Down syndrome. Furthermore, the NDC80 complex has been shown to play a role in the regulation of cell cycle progression, with dysregulation leading to increased cell proliferation and tumorigenesis. The NDC80 complex is also involved in the regulation of cell differentiation, with abnormalities in the complex contributing to the development of certain diseases, such as leukemia. In conclusion, the NDC80 gene is a critical component of the kinetochore complex, playing a pivotal role in the proper segregation of chromosomes during cell division. Its dysregulation has been implicated in various human diseases, highlighting the importance of this gene in maintaining genome stability and preventing tumorigenesis. **Significantly Expressed Cells:** The NDC80 gene is significantly expressed in various cell types, including: * Large pre-B-II cells * Migratory enteric neural crest cells * Immature innate lymphoid cells * Cerebral cortex GABAergic interneurons * Forebrain radial glial cells * Absorptive cells * Tuft cells of the colon * Cardiac endothelial cells * BEST4+ intestinal epithelial cells * Human intestinal crypt stem cells of the colon **Proteins:** The NDC80 gene encodes a single protein, Kinetochore protein NDC80 homolog (NDC80_HUMAN), which is a member of the NDC80 complex.

Genular Protein ID: 3264523557

Symbol: NDC80_HUMAN

Name: Kinetochore protein NDC80 homolog

UniProtKB Accession Codes:

O14777 Q6PJX2

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 2 EMDB 1 EPD 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 30 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 4 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 6 RefSeq 1 SAM 1 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9315664

Title: HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis.

PubMed ID: 9315664

DOI: 10.1128/mcb.17.10.6049

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9295362

Title: HEC binds to the seventh regulatory subunit of the 26 S proteasome and modulates the proteolysis of mitotic cyclins.

PubMed ID: 9295362

DOI: 10.1074/jbc.272.38.24081

PubMed ID: 10409732

Title: Hec1p, an evolutionarily conserved coiled-coil protein, modulates chromosome segregation through interaction with SMC proteins.

PubMed ID: 10409732

DOI: 10.1128/mcb.19.8.5417

PubMed ID: 10779342

Title: Retinoblastoma protein enhances the fidelity of chromosome segregation mediated by hsHec1p.

PubMed ID: 10779342

DOI: 10.1128/mcb.20.10.3529-3537.2000

PubMed ID: 12386167

Title: Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation.

PubMed ID: 12386167

DOI: 10.1074/jbc.m207069200

PubMed ID: 12351790

Title: Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2.

PubMed ID: 12351790

DOI: 10.1126/science.1075596

PubMed ID: 14654001

Title: Nuf2 and Hec1 are required for retention of the checkpoint proteins Mad1 and Mad2 to kinetochores.

PubMed ID: 14654001

DOI: 10.1016/j.cub.2003.10.056

PubMed ID: 15235793

Title: Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1.

PubMed ID: 15235793

DOI: 10.1007/s00412-004-0288-2

PubMed ID: 15062103

Title: The RanGAP1-RanBP2 complex is essential for microtubule-kinetochore interactions in vivo.

PubMed ID: 15062103

DOI: 10.1016/j.cub.2004.03.031

PubMed ID: 15239953

Title: Timing and checkpoints in the regulation of mitotic progression.

PubMed ID: 15239953

DOI: 10.1016/j.devcel.2004.06.006

PubMed ID: 15133482

Title: Sgt1 is required for human kinetochore assembly.

PubMed ID: 15133482

DOI: 10.1038/sj.embor.7400154

PubMed ID: 14699129

Title: Identification of two novel components of the human NDC80 kinetochore complex.

PubMed ID: 14699129

DOI: 10.1074/jbc.m310224200

PubMed ID: 14978040

Title: NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling.

PubMed ID: 14978040

DOI: 10.1074/jbc.m314205200

PubMed ID: 14602875

Title: Identification of the substrates and interaction proteins of aurora kinases from a protein-protein interaction model.

PubMed ID: 14602875

DOI: 10.1074/mcp.m300072-mcp200

PubMed ID: 15502821

Title: A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1.

PubMed ID: 15502821

DOI: 10.1038/ncb1187

PubMed ID: 15964272

Title: Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores.

PubMed ID: 15964272

DOI: 10.1016/j.cub.2005.05.026

PubMed ID: 15961401

Title: Architecture of the human Ndc80-Hec1 complex, a critical constituent of the outer kinetochore.

PubMed ID: 15961401

DOI: 10.1074/jbc.m504070200

PubMed ID: 15824131

Title: ZW10 links mitotic checkpoint signaling to the structural kinetochore.

PubMed ID: 15824131

DOI: 10.1083/jcb.200411118

PubMed ID: 15548592

Title: Hec1 and Nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.

PubMed ID: 15548592

DOI: 10.1091/mbc.e04-09-0852

PubMed ID: 15713649

Title: The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis.

PubMed ID: 15713649

DOI: 10.1128/mcb.25.5.1958-1970.2005

PubMed ID: 16732327

Title: Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control.

PubMed ID: 16732327

DOI: 10.1038/sj.onc.1209687

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23085020

Title: The kinetochore-bound Ska1 complex tracks depolymerizing microtubules and binds to curved protofilaments.

PubMed ID: 23085020

DOI: 10.1016/j.devcel.2012.09.012

PubMed ID: 22581055

Title: Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment.

PubMed ID: 22581055

DOI: 10.1038/ncb2489

PubMed ID: 23891108

Title: Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK.

PubMed ID: 23891108

DOI: 10.1016/j.cub.2013.06.040

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25743205

Title: Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules.

PubMed ID: 25743205

DOI: 10.1038/ncomms7447

PubMed ID: 27156448

Title: A TOG protein confers tension sensitivity to kinetochore-microtubule attachments.

PubMed ID: 27156448

DOI: 10.1016/j.cell.2016.04.030

PubMed ID: 30409912

Title: Dynamic acetylation of the kinetochore-associated protein HEC1 ensures accurate microtubule-kinetochore attachment.

PubMed ID: 30409912

DOI: 10.1074/jbc.ra118.003844

Sequence Information:

  • Length: 642
  • Mass: 73913
  • Checksum: 6A82DA4D8B77ECDC
  • Sequence:
    • MKRSSVSSGG AGRLSMQELR SQDVNKQGLY TPQTKEKPTF GKLSINKPTS ERKVSLFGKR 
TSGHGSRNSQ LGIFSSSEKI KDPRPLNDKA FIQQCIRQLC EFLTENGYAH NVSMKSLQAP 
SVKDFLKIFT FLYGFLCPSY ELPDTKFEEE VPRIFKDLGY PFALSKSSMY TVGAPHTWPH 
IVAALVWLID CIKIHTAMKE SSPLFDDGQP WGEETEDGIM HNKLFLDYTI KCYESFMSGA 
DSFDEMNAEL QSKLKDLFNV DAFKLESLEA KNRALNEQIA RLEQEREKEP NRLESLRKLK 
ASLQGDVQKY QAYMSNLESH SAILDQKLNG LNEEIARVEL ECETIKQENT RLQNIIDNQK 
YSVADIERIN HERNELQQTI NKLTKDLEAE QQKLWNEELK YARGKEAIET QLAEYHKLAR 
KLKLIPKGAE NSKGYDFEIK FNPEAGANCL VKYRAQVYVP LKELLNETEE EINKALNKKM 
GLEDTLEQLN AMITESKRSV RTLKEEVQKL DDLYQQKIKE AEEEDEKCAS ELESLEKHKH 
LLESTVNQGL SEAMNELDAV QREYQLVVQT TTEERRKVGN NLQRLLEMVA THVGSVEKHL 
EEQIAKVDRE YEECMSEDLS ENIKEIRDKY EKKATLIKSS EE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.