Details for: YAP1
Associated with
Other Information
Genular Protein ID: 4291393046
Symbol: YAP1_HUMAN
Name: Transcriptional coactivator YAP1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7782338
Title: Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain.
PubMed ID: 7782338
PubMed ID: 12807903
Title: WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus.
PubMed ID: 12807903
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 22939869
Title: Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene.
PubMed ID: 22939869
PubMed ID: 9202023
Title: Characterization of the WW domain of human Yes-associated protein and its polyproline containing ligands.
PubMed ID: 9202023
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16461361
Title: Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73.
PubMed ID: 16461361
PubMed ID: 17535448
Title: Regulation of p73 by Hck through kinase-dependent and independent mechanisms.
PubMed ID: 17535448
PubMed ID: 17974916
Title: Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.
PubMed ID: 17974916
DOI: 10.1101/gad.1602907
PubMed ID: 17502622
Title: Proline-rich Gla protein 2 is a cell-surface vitamin K-dependent protein that binds to the transcriptional coactivator Yes-associated protein.
PubMed ID: 17502622
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18579750
Title: TEAD mediates YAP-dependent gene induction and growth control.
PubMed ID: 18579750
DOI: 10.1101/gad.1664408
PubMed ID: 18158288
Title: Tumor suppressor LATS1 is a negative regulator of oncogene YAP.
PubMed ID: 18158288
PubMed ID: 18280240
Title: Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage.
PubMed ID: 18280240
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21364637
Title: JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis.
PubMed ID: 21364637
DOI: 10.1038/cddis.2010.7
PubMed ID: 21145499
Title: The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway.
PubMed ID: 21145499
PubMed ID: 20048001
Title: A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP).
PubMed ID: 20048001
DOI: 10.1101/gad.1843810
PubMed ID: 20123908
Title: Structural basis of YAP recognition by TEAD4 in the hippo pathway.
PubMed ID: 20123908
DOI: 10.1101/gad.1865310
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23873930
Title: Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.
PubMed ID: 23873930
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 22525271
Title: PTPN14 interacts with and negatively regulates the oncogenic function of YAP.
PubMed ID: 22525271
DOI: 10.1038/onc.2012.147
PubMed ID: 24462371
Title: Heterozygous loss-of-function mutations in YAP1 cause both isolated and syndromic optic fissure closure defects.
PubMed ID: 24462371
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25778702
Title: YAP is essential for tissue tension to ensure vertebrate 3D body shape.
PubMed ID: 25778702
DOI: 10.1038/nature14215
PubMed ID: 25849865
Title: Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking.
PubMed ID: 25849865
DOI: 10.1038/ncomms7781
PubMed ID: 28169360
Title: Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway.
PubMed ID: 28169360
DOI: 10.1038/srep42125
PubMed ID: 29400695
Title: Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis.
PubMed ID: 29400695
DOI: 10.1172/jci90429
PubMed ID: 30447097
Title: Identification of genes involved in the regulation of TERT in hepatocellular carcinoma.
PubMed ID: 30447097
DOI: 10.1111/cas.13884
PubMed ID: 11743730
Title: Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
PubMed ID: 11743730
PubMed ID: 11687614
Title: Using flexible loop mimetics to extend phi-value analysis to secondary structure interactions.
PubMed ID: 11687614
PubMed ID: 20123905
Title: Structural insights into the YAP and TEAD complex.
PubMed ID: 20123905
DOI: 10.1101/gad.1865810
PubMed ID: 21685363
Title: A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
PubMed ID: 21685363
DOI: 10.1101/gad.2060811
Sequence Information:
- Length: 504
- Mass: 54462
- Checksum: 6145F7049ED338AE
- Sequence:
MDPGQQPPPQ PAPQGQGQPP SQPPQGQGPP SGPGQPAPAA TQAAPQAPPA GHQIVHVRGD SETDLEALFN AVMNPKTANV PQTVPMRLRK LPDSFFKPPE PKSHSRQAST DAGTAGALTP QHVRAHSSPA SLQLGAVSPG TLTPTGVVSG PAATPTAQHL RQSSFEIPDD VPLPAGWEMA KTSSGQRYFL NHIDQTTTWQ DPRKAMLSQM NVTAPTSPPV QQNMMNSASG PLPDGWEQAM TQDGEIYYIN HKNKTTSWLD PRLDPRFAMN QRISQSAPVK QPPPLAPQSP QGGVMGGSNS NQQQQMRLQQ LQMEKERLRL KQQELLRQAM RNINPSTANS PKCQELALRS QLPTLEQDGG TQNPVSSPGM SQELRTMTTN SSDPFLNSGT YHSRDESTDS GLSMSSYSVP RTPDDFLNSV DEMDTGDTIN QSTLPSQQNR FPDYLEAIPG TNVDLGTLEG DGMNIEGEEL MPSLQEALSS DILNDMESVL AATKLDKESF LTWL
Genular Protein ID: 823182996
Symbol: Q86T74_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 397
- Mass: 43281
- Checksum: FDDC41A561116EF0
- Sequence:
TDAGTAGALT PQHVRAHSSP ASLQLGAVSP GTLTPTGVVS GPAATPTAQH LRQSSFEIPD DVPLPAGWEM AKTSSGQRYF LNHIDQTTTW QDPRKAMLSQ MNVTAPTSPP VQQNMMNSAS GPLPDGWEQA MTQDGEIYYI NHKNKTTSWL DPRLDPRFGK AMNQRISQSA PVKQPPPLAP QSPQGGVMGG SNSNQQQQMR LQQLQMEKER LRLKQQELLR QAMRNINPST ANSPKCQELA LRSQLPTLEQ DGGTQNPVSS PGMSQELRTM TTNSSDPFLN SGTYHSRDES TDSGLSMSSY SVPRTPDDFL NSVDEMDTGD TINQSTLPSQ QNRFPDYLEA IPGTNVDLGT LEGDGMNIEG EELMPSLQEA LSSDILNDME SVLAATKLDK ESFLTWL
Genular Protein ID: 3263209330
Symbol: K0KVU2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
Title: Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene.
Sequence Information:
- Length: 168
- Mass: 18714
- Checksum: 39A890B3505370A7
- Sequence:
MLSQMNVTAP TSPPVQQNMM NSASGPLPDG WEQAMTQDGE IYYINHKNKT TSWLDPRLDP RFAMNQRISQ SAPVKQPPPL APQSPQGGVM GGSNSNQQQQ MRLQQLQMEK ERLRLKQQEL LRQVRPQAMR NINPSTANSP KCQELALRSQ LPTLEQDGGT QNPVSSPG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.