Details for: LYPLA1

Gene ID: 10434

Symbol: LYPLA1

Ensembl ID: ENSG00000120992

Description: lysophospholipase 1

Associated with

Other Information

Genular Protein ID: 2622498628

Symbol: LYPA1_HUMAN

Name: Acyl-protein thioesterase 1

UniProtKB Accession Codes:

O75608 O43202 Q9UQF9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CPTAC 2 CTD 1 ChEBI 15 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 2 EMBL 7 EPD 1 ESTHER 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 6 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 6 Rhea 7 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11080636

Title: Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A.

PubMed ID: 11080636

DOI: 10.1016/s0969-2126(00)00529-3

PubMed ID: 11042152

Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.

PubMed ID: 11042152

DOI: 10.1101/gr.140200

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19439193

Title: Thioesterase activity and subcellular localization of acylprotein thioesterase 1/lysophospholipase 1.

PubMed ID: 19439193

DOI: 10.1016/j.bbalip.2009.05.001

PubMed ID: 20418879

Title: Small-molecule inhibition of APT1 affects Ras localization and signaling.

PubMed ID: 20418879

DOI: 10.1038/nchembio.362

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21393252

Title: The phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation.

PubMed ID: 21393252

DOI: 10.1194/jlr.m013326

PubMed ID: 22399288

Title: Distinct acyl protein transferases and thioesterases control surface expression of calcium-activated potassium channels.

PubMed ID: 22399288

DOI: 10.1074/jbc.m111.335547

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27481942

Title: S-Palmitoylation of a Novel Site in the beta2-Adrenergic Receptor Associated with a Novel Intracellular Itinerary.

PubMed ID: 27481942

DOI: 10.1074/jbc.m116.725762

Sequence Information:

  • Length: 230
  • Mass: 24670
  • Checksum: 90C0522F765F1AC6
  • Sequence:
    • MCGNNMSTPL PAIVPAARKA TAAVIFLHGL GDTGHGWAEA FAGIRSSHIK YICPHAPVRP 
VTLNMNVAMP SWFDIIGLSP DSQEDESGIK QAAENIKALI DQEVKNGIPS NRIILGGFSQ 
GGALSLYTAL TTQQKLAGVT ALSCWLPLRA SFPQGPIGGA NRDISILQCH GDCDPLVPLM 
FGSLTVEKLK TLVNPANVTF KTYEGMMHSS CQQEMMDVKQ FIDKLLPPID

Genular Protein ID: 4188856724

Symbol: A0A087X1K9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087X1K9

Database IDs:

ARBA 17 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 10 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 2 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 3 Rhea 4 SMR 1 SUPFAM 1 SwissPalm 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 166
  • Mass: 17981
  • Checksum: 5D22E625F99796C2
  • Sequence:
    • MNVAMPSWFD IIGLSPDSQE DESGIKQAAE NIKALIDQEV KNGIPSNRII LGGFSQGGAL 
SLYTALTTQQ KLAGVTALSC WLPLRASFPQ GPIGGANRDI SILQCHGDCD PLVPLMFGSL 
TVEKLKTLVN PANVTFKTYE GMMHSSCQQE MMDVKQFIDK LLPPID

Genular Protein ID: 3449828353

Symbol: B4DP64_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DP64

Database IDs:

ARBA 17 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 10 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 ESTHER 1 Ensembl 2 GO 1 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 2 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 4 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.M111.015131

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 196
  • Mass: 21123
  • Checksum: 92A418FDEE32A5F4
  • Sequence:
    • MCGNNMSTPL PAIVPAARKA TAAVIFLHGL GDTGHGWAEA FAGIRSSHIK YICPHAPVRP 
VTLNMNVAMP SWFDIIGLSP DSQEDESGIK QAAENIKALI DQEVKNGIPS NRIILGGFSQ 
GPIGGANRDI SILQCHGDCD PLVPLMFGSL TVEKLKTLVN PANVTFKTYE GMMHSSCQQE 
MMDVKQFIDK LLPPID

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.