ACAA2 | ENSG00000167315 | NCBI 10449

Details for: ACAA2

Gene ID: 10449

Symbol: ACAA2

Ensembl ID: ENSG00000167315

Description: acetyl-CoA acyltransferase 2

Associated with

Fatty acid metabolism
(R-HSA-8978868)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Mitochondrial fatty acid beta-oxidation
(R-HSA-77289)
Acetyl-coa c-acetyltransferase activity
(GO:0003985)
Acetyl-coa c-acyltransferase activity
(GO:0003988)
Acetyl-coa hydrolase activity
(GO:0003986)
Cellular response to hypoxia
(GO:0071456)
Cholesterol biosynthetic process
(GO:0006695)
Fatty acid beta-oxidation
(GO:0006635)
Fatty acyl-coa hydrolase activity
(GO:0047617)
Long-chain fatty acyl-coa hydrolase activity
(GO:0052816)
Mitochondrial matrix
(GO:0005759)
Mitochondrion
(GO:0005739)
Negative regulation of mitochondrial membrane permeability involved in apoptotic process
(GO:1902109)
Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
(GO:1901029)
Protein binding
(GO:0005515)
Rna binding
(GO:0003723)

Other Information

Proteins

Acetyl-CoA acyltransferase
B3KNP8_HUMAN

Genular Protein ID: 322475796

Symbol: THIM_HUMAN

Name: Acetyl-CoA acyltransferase

UniProtKB Accession Codes:

P42765 Q9BUT6

Database IDs:

Citations:

PubMed ID: 8241273

Title: Cloning and sequence analysis of a full length cDNA encoding human mitochondrial 3-oxoacyl-CoA thiolase.

PubMed ID: 8241273

DOI: 10.1016/0167-4781(93)90160-f

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15242332

Title: Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.

PubMed ID: 15242332

DOI: 10.1042/bj20040647

PubMed ID: 18371312

Title: Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines.

PubMed ID: 18371312

DOI: 10.1016/j.bbagen.2008.02.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 25478839

Title: The crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase (T1): insight into the reaction mechanism of its thiolase and thioesterase activities.

PubMed ID: 25478839

DOI: 10.1107/s1399004714023827

Sequence Information:

Length: 397
Mass: 41924
Checksum: 380CC8262ACF6D01
Sequence:

MALLRGVFVV AAKRTPFGAY GGLLKDFTAT DLSEFAAKAA LSAGKVSPET VDSVIMGNVL 
QSSSDAIYLA RHVGLRVGIP KETPALTINR LCGSGFQSIV NGCQEICVKE AEVVLCGGTE 
SMSQAPYCVR NVRFGTKLGS DIKLEDSLWV SLTDQHVQLP MAMTAENLAV KHKISREECD 
KYALQSQQRW KAANDAGYFN DEMAPIEVKT KKGKQTMQVD EHARPQTTLE QLQKLPPVFK 
KDGTVTAGNA SGVADGAGAV IIASEDAVKK HNFTPLARIV GYFVSGCDPS IMGIGPVPAI 
SGALKKAGLS LKDMDLVEVN EAFAPQYLAV ERSLDLDISK TNVNGGAIAL GHPLGGSGSR 
ITAHLVHELR RRGGKYAVGS ACIGGGQGIA VIIQSTA

Genular Protein ID: 1595586712

Symbol: B3KNP8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KNP8

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

Length: 397
Mass: 41896
Checksum: EF4467C17ACF7F98
Sequence:

MALLRGVFVV AAKRTPFGAY GGLLKDFTAT DLSEFAAKAA LSAGKVSPET VDSVIMGNVL 
QSSSDAIYLA RHVGLRVGIP KETPALTINR LCGSGFQSIV NGCQEICVKE AEVVLCGGTE 
SMSQAPYCVR NVRFGTKLGS DIKLEDSLWV SLTDQHVQLP MAMTAENLAV KHKISREECD 
KYALQSQQRW KAANDAGYFN DEMAPIEVKT KKGKQTMQVD EHARPQTTLE QLQKLPPVFK 
KDGTVTAGNA SGVADGAGAV IIASEDAVKK HNFTPLARIV GYFVSGCDPS IMGIGPVPAI 
SGALKKAGLS LKDMDLVEAN EAFAPQYLAV ERSLDLDISK TNVNGGAIAL GHPLGGSGSR 
ITAHLVHELR RRGGKYAVGS ACIGGGQGIA VIIQSTA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ACAA2

Associated with

Other Information

Cloning and sequence analysis of a full length cDNA encoding human mitochondrial 3-oxoacyl-CoA thiolase. PubMed ID: 8241273

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes. PubMed ID: 15242332

Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines. PubMed ID: 18371312

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Initial characterization of the human central proteome. PubMed ID: 21269460

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

The crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase (T1): insight into the reaction mechanism of its thiolase and thioesterase activities. PubMed ID: 25478839

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039