Details for: HAX1
Associated with
Other Information
Genular Protein ID: 2080216403
Symbol: HAX1_HUMAN
Name: HCLS1-associated protein X-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9058808
Title: HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases.
PubMed ID: 9058808
PubMed ID: 18472110
Title: Existence of multiple isoforms of HS1-associated protein X-1 in murine and human tissues.
PubMed ID: 18472110
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10760273
Title: The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton.
PubMed ID: 10760273
PubMed ID: 15339924
Title: Galpha13 stimulates cell migration through cortactin-interacting protein Hax-1.
PubMed ID: 15339924
PubMed ID: 16857965
Title: Overexpression of HAX-1 protects cardiac myocytes from apoptosis through caspase-9 inhibition.
PubMed ID: 16857965
PubMed ID: 17545607
Title: HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin alphavbeta6.
PubMed ID: 17545607
PubMed ID: 17241641
Title: Phospholamban interacts with HAX-1, a mitochondrial protein with anti-apoptotic function.
PubMed ID: 17241641
PubMed ID: 17187068
Title: HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease).
PubMed ID: 17187068
DOI: 10.1038/ng1940
PubMed ID: 18337561
Title: Novel HAX1 mutations in patients with severe congenital neutropenia reveal isoform-dependent genotype-phenotype associations.
PubMed ID: 18337561
PubMed ID: 18319618
Title: HS 1-associated protein X-1 is cleaved by caspase-3 during apoptosis.
PubMed ID: 18319618
PubMed ID: 18971376
Title: The anti-apoptotic protein HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival.
PubMed ID: 18971376
PubMed ID: 20171186
Title: Molecular interaction between HAX-1 and XIAP inhibits apoptosis.
PubMed ID: 20171186
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 20665473
Title: Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation.
PubMed ID: 20665473
DOI: 10.1002/jmr.1062
PubMed ID: 23164465
Title: HAX-1 is a nucleocytoplasmic shuttling protein with a possible role in mRNA processing.
PubMed ID: 23164465
DOI: 10.1111/febs.12066
PubMed ID: 24188827
Title: Hax-1 identified as a two-pore channel (TPC)-binding protein.
PubMed ID: 24188827
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25298122
Title: Identification and characterization of OSTL (RNF217) encoding a RING-IBR-RING protein adjacent to a translocation breakpoint involving ETV6 in childhood ALL.
PubMed ID: 25298122
DOI: 10.1038/srep06565
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 26915802
Title: UCP3 is associated with Hax-1 in mitochondria in the presence of calcium ion.
PubMed ID: 26915802
PubMed ID: 26997484
Title: Kv3.3 channels bind Hax-1 and Arp2/3 to assemble a stable local actin network that regulates channel gating.
PubMed ID: 26997484
PubMed ID: 19796188
Title: A novel missense mutation in the HAX1 gene in severe congenital neutropenia patients (Kostmann disease).
PubMed ID: 19796188
PubMed ID: 20220065
Title: Digenic mutations in severe congenital neutropenia.
PubMed ID: 20220065
Sequence Information:
- Length: 279
- Mass: 31621
- Checksum: 87EEF0C46857704B
- Sequence:
MSLFDLFRGF FGFPGPRSHR DPFFGGMTRD EDDDEEEEEE GGSWGRGNPR FHSPQHPPEE FGFGFSFSPG GGIRFHDNFG FDDLVRDFNS IFSDMGAWTL PSHPPELPGP ESETPGERLR EGQTLRDSML KYPDSHQPRI FGGVLESDAR SESPQPAPDW GSQRPFHRFD DVWPMDPHPR TREDNDLDSQ VSQEGLGPVL QPQPKSYFKS ISVTKITKPD GIVEERRTVV DSEGRTETTV TRHEADSSPR GDPESPRPPA LDDAFSILDL FLGRWFRSR
Genular Protein ID: 2822398247
Symbol: A0A0S2Z565_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 26871637
Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
PubMed ID: 26871637
Sequence Information:
- Length: 231
- Mass: 26100
- Checksum: 25EF194EC019C474
- Sequence:
MSLFDLFRGF FGFPGPRSFS PGGGIRFHDN FGFDDLVRDF NSIFSDMGAW TLPSHPPELP GPESETPGER LREGQTLRDS MLKYPDSHQP RIFGGVLESD ARSESPQPAP DWGSQRPFHR FDDVWPMDPH PRTREDNDLD SQVSQEGLGP VLQPQPKSYF KSISVTKITK PDGIVEERRT VVDSEGRTET TVTRHEADSS PRGDPESPRP PALDDAFSIL DLFLGRWFRS R
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.