Details for: BAIAP2

Gene ID: 10458

Symbol: BAIAP2

Ensembl ID: ENSG00000175866

Description: BAR/IMD domain containing adaptor protein 2

Associated with

Other Information

Genular Protein ID: 572965329

Symbol: BAIP2_HUMAN

Name: Brain-specific angiogenesis inhibitor 1-associated protein 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10343108

Title: Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1.

PubMed ID: 10343108

DOI: 10.1159/000015219

PubMed ID: 10332026

Title: Dentatorubral-pallidoluysian atrophy protein interacts through a proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate.

PubMed ID: 10332026

DOI: 10.1093/hmg/8.6.947

PubMed ID: 12884081

Title: Genomic structure and alternative splicing of the insulin receptor tyrosine kinase substrate of 53-kDa protein.

PubMed ID: 12884081

DOI: 10.1007/s10038-003-0047-x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11130076

Title: IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling.

PubMed ID: 11130076

DOI: 10.1038/35047107

PubMed ID: 11696321

Title: Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex.

PubMed ID: 11696321

DOI: 10.1016/s0960-9822(01)00506-1

PubMed ID: 11157984

Title: Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin.

PubMed ID: 11157984

DOI: 10.1083/jcb.152.3.579

PubMed ID: 12504591

Title: The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42.

PubMed ID: 12504591

DOI: 10.1006/mcne.2002.1201

PubMed ID: 15289329

Title: IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness.

PubMed ID: 15289329

DOI: 10.1158/0008-5472.can-04-0327

PubMed ID: 14752106

Title: A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein.

PubMed ID: 14752106

DOI: 10.1074/jbc.m309408200

PubMed ID: 17115031

Title: Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complex.

PubMed ID: 17115031

DOI: 10.1038/ncb1502

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19286134

Title: IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation.

PubMed ID: 19286134

DOI: 10.1016/j.chom.2009.02.003

PubMed ID: 19366662

Title: Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation.

PubMed ID: 19366662

DOI: 10.1073/pnas.0809131106

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 15635447

Title: Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53.

PubMed ID: 15635447

DOI: 10.1038/sj.emboj.7600535

Sequence Information:

  • Length: 552
  • Mass: 60868
  • Checksum: 3B9EDC6405DCC99D
  • Sequence:
  • MSLSRSEEMH RLTENVYKTI MEQFNPSLRN FIAMGKNYEK ALAGVTYAAK GYFDALVKMG 
    ELASESQGSK ELGDVLFQMA EVHRQIQNQL EEMLKSFHNE LLTQLEQKVE LDSRYLSAAL 
    KKYQTEQRSK GDALDKCQAE LKKLRKKSQG SKNPQKYSDK ELQYIDAISN KQGELENYVS 
    DGYKTALTEE RRRFCFLVEK QCAVAKNSAA YHSKGKELLA QKLPLWQQAC ADPSKIPERA 
    VQLMQQVASN GATLPSALSA SKSNLVISDP IPGAKPLPVP PELAPFVGRM SAQESTPIMN 
    GVTGPDGEDY SPWADRKAAQ PKSLSPPQSQ SKLSDSYSNT LPVRKSVTPK NSYATTENKT 
    LPRSSSMAAG LERNGRMRVK AIFSHAAGDN STLLSFKEGD LITLLVPEAR DGWHYGESEK 
    TKMRGWFPFS YTRVLDSDGS DRLHMSLQQG KSSSTGNLLD KDDLAIPPPD YGAASRAFPA 
    QTASGFKQRP YSVAVPAFSQ GLDDYGARSM SRNPFAHVQL KPTVTNDRCD LSAQGPEGRE 
    HGDGSARTLA GR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.