Details for: PIBF1

Gene ID: 10464

Symbol: PIBF1

Ensembl ID: ENSG00000083535

Description: progesterone immunomodulatory binding factor 1

Associated with

Other Information

Genular Protein ID: 3989411037

Symbol: PIBF1_HUMAN

Name: Progesterone-induced-blocking factor 1

UniProtKB Accession Codes:

Q8WXW3 O95664 Q6U9V2 Q6UG50 Q86V07 Q96SF4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 19 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 1 SAM 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11935316

Title: A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes.

PubMed ID: 11935316

DOI: 10.1007/s00439-001-0646-6

PubMed ID: 15305375

Title: PIBF (progesterone induced blocking factor) is overexpressed in highly proliferating cells and associated with the centrosome.

PubMed ID: 15305375

DOI: 10.1002/ijc.20326

PubMed ID: 14634107

Title: Molecular cloning and immunologic characterization of a novel cDNA coding for progesterone-induced blocking factor.

PubMed ID: 14634107

DOI: 10.4049/jimmunol.171.11.5956

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3863495

Title: The mechanism of the inhibitory effect of progesterone on lymphocyte cytotoxicity: I. Progesterone-treated lymphocytes release a substance inhibiting cytotoxicity and prostaglandin synthesis.

PubMed ID: 3863495

DOI: 10.1111/j.1600-0897.1985.tb00334.x

PubMed ID: 11407300

Title: Progesterone as an immunomodulatory molecule.

PubMed ID: 11407300

DOI: 10.1016/s1567-5769(01)00035-2

PubMed ID: 12516630

Title: Progesterone induced blocking factor (PIBF) mediates progesterone induced suppression of decidual lymphocyte cytotoxicity.

PubMed ID: 12516630

DOI: 10.1034/j.1600-0897.2002.01133.x

PubMed ID: 12733588

Title: Progesterone regulates IL12 expression in pregnancy lymphocytes by inhibiting phospholipase A2.

PubMed ID: 12733588

DOI: 10.1034/j.1600-0897.2003.01149.x

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15269099

Title: Urinary progesterone-induced blocking factor concentration is related to pregnancy outcome.

PubMed ID: 15269099

DOI: 10.1095/biolreprod.104.030437

PubMed ID: 16393965

Title: Progesterone-induced blocking factor activates STAT6 via binding to a novel IL-4 receptor.

PubMed ID: 16393965

DOI: 10.4049/jimmunol.176.2.819

PubMed ID: 18817979

Title: Human trophoblast cells express the immunomodulator progesterone-induced blocking factor.

PubMed ID: 18817979

DOI: 10.1016/j.jri.2008.06.002

PubMed ID: 21224392

Title: The pericentriolar satellite protein CEP90 is crucial for integrity of the mitotic spindle pole.

PubMed ID: 21224392

DOI: 10.1242/jcs.078329

PubMed ID: 23110211

Title: CEP90 is required for the assembly and centrosomal accumulation of centriolar satellites, which is essential for primary cilia formation.

PubMed ID: 23110211

DOI: 10.1371/journal.pone.0048196

PubMed ID: 25218441

Title: Progesterone-induced blocking factor is hormonally regulated in human astrocytoma cells, and increases their growth through the IL-4R/JAK1/STAT6 pathway.

PubMed ID: 25218441

DOI: 10.1016/j.jsbmb.2014.09.007

PubMed ID: 26297806

Title: Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication.

PubMed ID: 26297806

DOI: 10.7554/elife.07519

PubMed ID: 26167768

Title: An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes.

PubMed ID: 26167768

DOI: 10.1038/ncb3201

Sequence Information:

  • Length: 757
  • Mass: 89805
  • Checksum: B469FB3BCC7E80FD
  • Sequence:
    • MSRKISKESK KVNISSSLES EDISLETTVP TDDISSSEER EGKVRITRQL IERKELLHNI 
QLLKIELSQK TMMIDNLKVD YLTKIEELEE KLNDALHQKQ LLTLRLDNQL AFQQKDASKY 
QELMKQEMET ILLRQKQLEE TNLQLREKAG DVRRNLRDFE LTEEQYIKLK AFPEDQLSIP 
EYVSVRFYEL VNPLRKEICE LQVKKNILAE ELSTNKNQLK QLTETYEEDR KNYSEVQIRC 
QRLALELADT KQLIQQGDYR QENYDKVKSE RDALEQEVIE LRRKHEILEA SHMIQTKERS 
ELSKEVVTLE QTVTLLQKDK EYLNRQNMEL SVRCAHEEDR LERLQAQLEE SKKAREEMYE 
KYVASRDHYK TEYENKLHDE LEQIRLKTNQ EIDQLRNASR EMYERENRNL REARDNAVAE 
KERAVMAEKD ALEKHDQLLD RYRELQLSTE SKVTEFLHQS KLKSFESERV QLLQEETARN 
LTQCQLECEK YQKKLEVLTK EFYSLQASSE KRITELQAQN SEHQARLDIY EKLEKELDEI 
IMQTAEIENE DEAERVLFSY GYGANVPTTA KRRLKQSVHL ARRVLQLEKQ NSLILKDLEH 
RKDQVTQLSQ ELDRANSLLN QTQQPYRYLI ESVRQRDSKI DSLTESIAQL EKDVSNLNKE 
KSALLQTKNQ MALDLEQLLN HREELAAMKQ ILVKMHSKHS ENSLLLTKTE PKHVTENQKS 
KTLNVPKEHE DNIFTPKPTL FTKKEAPEWS KKQKMKT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.